中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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生态环境研究中心 [108]
上海药物研究所 [40]
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期刊论文 [311]
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Toxin metalloproteinases exert a dominant influence on pro-inflammatory response and anti-inflammatory regulation in jellyfish sting dermatitis
期刊论文
OAI收割
JOURNAL OF PROTEOMICS, 2024, 卷号: 292, 页码: 13
作者:
Yu, Chunlin
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/04/07
Jellyfish sting
Metalloproteinase
Differential analysis
Signal pathway
Dermatitis mechanism
A rationally designed fluorescence probe achieves highly specific and long-term detection of senescence in vitro and in vivo
期刊论文
OAI收割
AGING CELL, 2023, 页码: 14
作者:
Hu, Li
;
Dong, Chanjuan
;
Wang, Zhe
;
He, Shengyuan
;
Yang, Yiwen
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/10/17
aging
fibrosis
near-infrared probe
senescent cells
beta-galactosidase
Discovery of orally effective and safe GPR40 agonists by incorporating a chiral, rigid and polar sulfoxide into 8-position to the carboxylic acid
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 251, 页码: 115267
作者:
Chen, Cheng
;
Guo, Shi-Meng
;
Sun, Yuanjun
;
Li, He
;
Hu, Nan
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/03/27
GPR40
Glucose-stimulated insulin secretion
Type 2 diabetes mellitus
Lipophilicity
Liver safety
Three-in-one pharmacophore
2-(phenylsulfinyl)acetic acid
Single and combined effects of microplastics and cadmium on the sea cucumber Apostichopus japonicus
期刊论文
OAI收割
MARINE ENVIRONMENTAL RESEARCH, 2023, 卷号: 186, 页码: 11
作者:
Zhang, Chenxi
;
Lin, Chenggang
;
Li, Lingling
;
Mohsen, Mohamed
;
Wang, Ting
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2023/12/13
Microplastics
Cadmium
Microbiota
Sea cucumber
Combined toxicity
Meta-analysis reveals the species-, dose- and duration-dependent effects of cadmium toxicities in marine bivalves
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 859, 页码: 10
作者:
Zhan, Junfei
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收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/08/17
Adaptive mechanism
Dose -response
Marine bivalves
Toxicological endpoints
Trace metal
The design of small-molecule prodrugs and activatable phototherapeutics for cancer therapy
期刊论文
OAI收割
CHEMICAL SOCIETY REVIEWS, 2023, 卷号: 52, 期号: 3, 页码: 879-920
作者:
Han, Hai-Hao
;
Wang, Han-Min
;
Jangili, Paramesh
;
Li, Mingle
;
Wu, Luling
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收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/04/10
Discovery of Highly Potent Nicotinamide Phosphoribosyltransferase Degraders for Efficient Treatment of Ovarian Cancer
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 15
作者:
Bi, Kaijian
;
Cheng, Junfei
;
He, Shipeng
;
Fang, Yuxin
;
Huang, Min
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收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
Targeting the PI3K/AKT/mTOR Signaling Pathway in the Treatment of Human Diseases: Current Status, Trends, and Solutions
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 29
作者:
Huang, Jindi
;
Chen, Liye
;
Wu, Jiangxia
;
Ai, Daiqiao
;
Zhang, Ji-Quan
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/04/10
Multiple-dose up-titration study to evaluate the pharmacokinetics, safety and antitumor activity of apatinib in advanced gastric adenocarcinoma
期刊论文
OAI收割
FRONTIERS IN ONCOLOGY, 2022, 卷号: 12, 页码: 10
作者:
Wang, Yonggang
;
Wang, Chang
;
Zhang, Yanqiao
;
Hao, Jiqing
;
Yang, Nong
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/12/13
apatinib
angiogenesis
gastric adenocarcinoma
pharmacokinetics
VEGFR
VEGFR-2
A Peritumorally Injected Immunomodulating Adjuvant Elicits Robust and Safe Metalloimmunotherapy against Solid Tumors
期刊论文
OAI收割
ADVANCED MATERIALS, 2022, 页码: 12
作者:
Zhang, Lingxiao
;
Zhao, Jing
;
Hu, Xi
;
Wang, Chenhan
;
Jia, Yingbo
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/02/24
immunogenic cell death
layered double hydroxide
nutritional metal ions
tumor microenvironment
vaccine adjuvants