机构

• 上海药物研究所 [16]

采集方式

• OAI收割 [16]

内容类型

• 期刊论文 [16]

发表日期

• 2024 [1]
• 2023 [2]
• 2022 [2]
• 2020 [1]
• 2018 [2]
• 2017 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共16条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 PRMT1 Inhibition Activates the Interferon Pathway to Potentiate Antitumor Immunity and Enhance Checkpoint Blockade Efficacy in Melanoma 期刊论文  OAI收割 CANCER RESEARCH, 2024, 卷号: 84, 期号: 3, 页码: 419-433 作者:  Tao, Hongru;  Jin, Chen;  Zhou, Liyuan;  Deng, Zhenzhong;  Li, Xiao   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/04/09 Chemical Inhibitors Targeting the Oncogenic m6A Modifying Proteins 期刊论文  OAI收割 ACCOUNTS OF CHEMICAL RESEARCH, 2023, 卷号: 56, 期号: 21, 页码: 3010-3022 作者:  Huang, Yue;  Xia, Wenyang;  Dong, Ze;  Yang, Cai-Guang   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/11 A patent review of PRMT5 inhibitors to treat cancer (2018-present) 期刊论文  OAI收割 EXPERT OPINION ON THERAPEUTIC PATENTS, 2023, 页码: 28 作者:  Gao, Jing;  Yang, Jie;  Xue, Shengyu;  Ding, Hong;  Lin, Hua   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/10/17 PRMT5  inhibitor  epigenetic target  cancer treatment  combined treatment   Design, synthesis, and biological evaluation of novel carbazole derivatives as potent DNMT1 inhibitors with reasonable PK properties 期刊论文  OAI收割 JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1537-1555 作者:  Li, Ennian;  Wang, Kai;  Zhang, Bei;  Guo, Siqi;  Xiao, Senhao   |  收藏  |  浏览/下载：37/0  |  提交时间：2022/08/16 DNMT1 inhibitor  A549 cell lines  HCT116 cell lines  antitumor activity  pharmacokinetic   High-Throughput-Methyl-Reading (HTMR) assay: a solution based on nucleotide methyl-binding proteins enables large-scale screening for DNA/RNA methyltransferases and demethylases 期刊论文  OAI收割 NUCLEIC ACIDS RESEARCH, 2022, 卷号: 50, 期号: 2, 页码: 14 作者:  Xiao, Senhao;  Guo, Siqi;  Han, Jie;  Sun, Yanli;  Wang, Mingchen   |  收藏  |  浏览/下载：29/0  |  提交时间：2022/06/15 The cross-talk between methylation and phosphorylation in lymphoid-specific helicase drives cancer stem-like properties 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 卷号: 5, 期号: 1, 页码: 14 作者:  Liu, Na;  Yang, Rui;  Shi, Ying;  Chen, Ling;  Liu, Yating   |  收藏  |  浏览/下载：37/0  |  提交时间：2020/12/21 Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1 期刊论文  OAI收割 ACS CHEMICAL BIOLOGY, 2018, 卷号: 13, 期号: 3, 页码: 772-781 作者:  Ye, Fei;  Kong, Xiangqian;  Zhang, Hao;  Liu, Yan;  Shao, Zhiyuan   |  收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 Detection of PRMT1 inhibitors with stopped flow fluorescence 期刊论文  OAI收割 Signal transduction and targeted therapy, 2018, 卷号: 3, 页码: 6 作者:  Qian, Kun;  Hu, Hao;  Xu, Hui;  Zheng, Y George   |  收藏  |  浏览/下载：59/0  |  提交时间：2019/01/08 Discovery of novel DNA methyltransferase 3A inhibitors via structure-based virtual screening and biological assays 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 2, 页码: 342-346 作者:  Shao, Zhiyuan;  Xu, Pan;  Xu, Wen;  Li, Linjuan;  Liu, Shien   |  收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 Epigenetics  DNMT3A inhibitors  Virtual screening  Molecular docking   Histone lysine methyltransferases as anti-cancer targets for drug discovery 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1273-1280 作者:  Liu, Qing;  Wang, Ming-wei   |  收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 histone methyltransferases  adenosylmethionine  small molecule inhibitors  anti-cancer drugs  epigenetic modification  drug discovery