中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [111]
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OAI收割 [111]
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期刊论文 [108]
学位论文 [2]
会议论文 [1]
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2022 [4]
2020 [3]
2019 [7]
2018 [9]
2017 [4]
2016 [7]
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Oncology [2]
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共111条,第1-10条
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专题:上海药物研究所
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Suppression of Pathological Ocular Neovascularization by a Small Molecular Multi-Targeting Kinase Inhibitor, DCZ19903
期刊论文
OAI收割
TRANSLATIONAL VISION SCIENCE & TECHNOLOGY, 2022, 卷号: 11, 期号: 12, 页码: 15
作者:
Ding, Jingjuan
;
Li, Bo
;
Zhang, Huiying
;
Xu, Zhijian
;
Zhang, Qiuyang
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/10/17
ocular neovascularization
DCZ19903
multitarget kinase inhibitor
network pharmacology
MAPK signaling pathway
Multiple-dose up-titration study to evaluate the pharmacokinetics, safety and antitumor activity of apatinib in advanced gastric adenocarcinoma
期刊论文
OAI收割
FRONTIERS IN ONCOLOGY, 2022, 卷号: 12, 页码: 10
作者:
Wang, Yonggang
;
Wang, Chang
;
Zhang, Yanqiao
;
Hao, Jiqing
;
Yang, Nong
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/12/13
apatinib
angiogenesis
gastric adenocarcinoma
pharmacokinetics
VEGFR
VEGFR-2
Dual-responsive nanoparticles loading bevacizumab and gefitinib for molecular targeted therapy against non-small cell lung cancer
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 11
作者:
Zhao, Zi-tong
;
Wang, Jue
;
Fang, Lei
;
Qian, Xin-di
;
Cai, Ying
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/08/16
nanoparticles
molecular targeted therapy
non-small cell lung cancer
dual-responsive
controlled release
Design and semisynthesis of oleanolic acid derivatives as VEGF in- hibitors: Inhibition of VEGF-induced proliferation, angiogenesis, and VEGFR2 activation in HUVECs
期刊论文
OAI收割
CHINESE JOURNAL OF NATURAL MEDICINES, 2022, 卷号: 20, 期号: 3, 页码: 229-240
作者:
Meng Ning
;
Xie Hong-Xu
;
Hou Jia-Rong
;
Chen Yon-Bin
;
Wu Meng-Jun
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/06/15
Oleanolic acid
Structural modification
VEGF inhibitor
VEGFR2
Angiogenesis
A pentapeptide enabled AL3810 liposome-based glioma-targeted therapy with immune opsonic effect attenuated
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 1, 页码: 283-299
作者:
Li, Jinyang
;
Lu, Jiasheng
;
Guo, Haiyan
;
Zhou, Jianfen
;
Wang, Songli
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/05/24
Liposome
mn
c(RGDyK)
Immune opsonization
Immunogenicity
Anti-glioma efficacy
Emerging roles of class I PI3K inhibitors in modulating tumor microenvironment and immunity
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Sun, Pu
;
Meng, Ling-hua
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/21
phosphoinositide 3-kinase (PI3K)
PI3K inhibitors
tumor microenvironment
immune cells
immunotherapy
Regulation of hypoxia-inducible factor functions in the nucleus by sphingosine-1-phosphate
期刊论文
OAI收割
FASEB JOURNAL, 2020, 页码: 18
作者:
Hait, Nitai C.
;
Maiti, Aparna
;
Xu, Pan
;
Qi, Qianya
;
Kawaguchi, Tsutomu
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
hypoxia-inducible factors
sphingosine-1-phosphate
sphingosine kinase 2
triple-negative breast cancer
Inhibition of Tumor Lymphangiogenesis is an Important Part that EGFR-TKIs Play in the Treatment of NSCLC
期刊论文
OAI收割
JOURNAL OF CANCER, 2020, 卷号: 11, 期号: 1, 页码: 241-250
作者:
Zhang, Yan
;
Yang, Xinying
;
Liu, Hongchun
;
Cai, Minghui
;
Yang Shentu
  |  
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2020/07/01
EGFR-TKIs
NSCLC
lymphangiogenesis
JAK/STAT3
LYVE-1
DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models
期刊论文
OAI收割
ARTHRITIS RESEARCH & THERAPY, 2019, 卷号: 21, 期号: 1, 页码: 15
作者:
Zhang, Zongwang
;
Wu, Yanwei
;
Wu, Bing
;
Qi, Qing
;
Li, Heng
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
Systemic sclerosis
SAHH inhibitor
Fibrosis
Inflammation
Vasculopathy
TGF-beta
Preclinical evaluation of 3D185, a novel potent inhibitor of FGFR1/2/3 and CSF-1R, in FGFR-dependent and macrophage-dominant cancer models
期刊论文
OAI收割
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2019, 卷号: 38, 期号: 1, 页码: 16
作者:
Peng, Xia
;
Hou, Pengcong
;
Chen, Yi
;
Dai, Yang
;
Ji, Yinchun
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
Kinase inhibitor
FGFR
CSF-1R
Tumor microenvironment