中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [105]
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期刊论文 [374]
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Synthesis, evaluation and molecular dynamics study of human toll-like receptor 2/6 specific monoacyl lipopeptides as candidate immunostimulants
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 141, 页码: 17
作者:
Zhu, Yueyue
;
Liu, Bo
;
Chen, Zonglong
;
Wang, Xianyang
;
Wang, Yujie
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
Toll -like receptor 2/6 agonists
PamCS
Structure-activity relationship
Lipopeptide
Immunostimulants
Gut Microbiota Metabolite 3-Indolepropionic Acid Directly Activates Hepatic Stellate Cells by ROS/JNK/p38 Signaling Pathways
期刊论文
OAI收割
BIOMOLECULES, 2023, 卷号: 13, 期号: 10, 页码: 14
作者:
Yuan, Xiaoyan
;
Yang, Junting
;
Huang, Yuling
;
Li, Jia
;
Li, Yuanyuan
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/08
gut-liver axis
3-Indolepropionic acid
HSCs
liver fibrosis
Flavonoids from Hippophae rhamnoides Linn. Revert Doxorubicin-Induced Cardiotoxicity through Inhibition of Mitochondrial Dysfunction in H9c2 Cardiomyoblasts In Vitro
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 4
作者:
Zhou, Wenna
;
Ouyang, Jian
;
Hu, Na
;
Wang, Honglun
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/01
Highly efficient enzymolysis and fermentation of corn stalk into L-lactic acid by enzyme-bacteria friendly ionic liquid pretreatment
期刊论文
OAI收割
Green Chemical Engineering, 2022, 卷号: 3, 期号: 4, 页码: 321-327
作者:
Yang, Yongqing
;
Wang, Yuehai
;
Lu, Xingmei
;
Zheng, Xu
;
Yan, Dongxia
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2023/06/26
Suppression of Pathological Ocular Neovascularization by a Small Molecular Multi-Targeting Kinase Inhibitor, DCZ19903
期刊论文
OAI收割
TRANSLATIONAL VISION SCIENCE & TECHNOLOGY, 2022, 卷号: 11, 期号: 12, 页码: 15
作者:
Ding, Jingjuan
;
Li, Bo
;
Zhang, Huiying
;
Xu, Zhijian
;
Zhang, Qiuyang
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/10/17
ocular neovascularization
DCZ19903
multitarget kinase inhibitor
network pharmacology
MAPK signaling pathway
Tribulus terrestris L. extract ameliorates atherosclerosis by inhibition of vascular smooth muscle cell proliferation in ApoE(-/-) mice and A7r5 cells via suppression of Akt/MEK/ERK signaling
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2022, 卷号: 297, 页码: 15
作者:
Zhang, Jing
;
Zhao, Wai-Rong
;
Shi, Wen-Ting
;
Tan, Jun-Jie
;
Zhang, Kai-Yu
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
Plaque progression
Hyperlipidemia
Mitogen-activated protein kinases
Oxidized low density lipoprotein
VSMC phenotype Switching
E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of MEKK2
期刊论文
OAI收割
EMBO REPORTS, 2022
作者:
Li, Hui
;
Wang, Ning
;
Jiang, Yu
;
Wang, Haofei
;
Xin, Zengfeng
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/12/22
IL-17R signaling
inflammation
MEKK2
NEDD4L
ubiquitination
Upregulation of dynorphin/kappa opioid receptor system in the dorsal hippocampus contributes to morphine withdrawal-induced place aversion
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 8
作者:
Chen, Yan
;
Wang, Chen-yao
;
Zan, Gui-ying
;
Yao, Song-yu
;
Deng, Ying-zhi
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/11/11
morphine withdrawal
conditioned place aversion
kappa opioid receptor
p38 MAPK
norBNI
dorsal hippocampus
Small molecule QF84139 ameliorates cardiac hypertrophy via activating the AMPK signaling pathway
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 3, 页码: 588-601
作者:
Li,Xu-xia
;
Zhang,Peng
;
Yang,Yang
;
Wang,Jing-jing
;
Zheng,Yan-jun
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/04/02
cardiac hypertrophy
pyrazine derivative
QF84139
phenylephrine
transverse aortic constriction
AMPK signaling pathway
PROTEIN-KINASE
MAMMALIAN TARGET
OVERLOAD
METFORMIN
MACROPHAGES
MECHANISMS
MEDICINE
ALPHA
CELLS
MODEL
Anti-inflammatory activity of Anchusa italica Retz. in LPS-stimulated RAW264.7 cells mediated by the Nrf2/HO-1, MAPK and NF-κB signaling pathways
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2022, 卷号: 286, 期号: 3, 页码: 1-9
作者:
Duan, XM (Duan, Xiaomei) [1] , [2]
;
Li, J (Li, Jun) [1] , [2]
;
Cui, JX (Cui, Jingxue) [1] , [2]
;
Dong, YW (Dong, Yuwei) [1] , [2]
;
Xin, XL (Xin, Xuelei) [1] , [2]
  |  
收藏
  |  
浏览/下载:158/0
  |  
提交时间:2022/05/17
Boraginaceae
Anchusa italica Retz.
Anti-inflammatory