中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [30]
采集方式
OAI收割 [30]
内容类型
期刊论文 [30]
发表日期
2021 [30]
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专题:上海药物研究所
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发表日期:2021
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Superior Dissolution Behavior and Bioavailability of Pharmaceutical Cocrystals and Recent Regulatory Issues
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2021, 页码: 9
作者:
Xia, Meng Y.
;
Zhu, Bing Q.
;
Wang, Jian-R
;
Yang, Ze E.
;
Mei, Xue F.
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/06/15
Pharmaceutical cocrystals
solubility
dissolution
bioavailability
IVIVC
patentability
Requirments for primary human hepatocyte
期刊论文
OAI收割
CELL PROLIFERATION, 2021, 页码: 6
作者:
Peng, Zhaoliang
;
Wu, Jiaying
;
Hu, Shijun
;
Ma, Aijin
;
Wang, Lei
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/06/15
primary human hepatocyte
quality control
standard
STING inhibitor ameliorates LPS-induced ALI by preventing vascular endothelial cells-mediated immune cells chemotaxis and adhesion
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Wu, Bing
;
Xu, Meng-meng
;
Fan, Chen
;
Feng, Chun-lan
;
Lu, Qiu-kai
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2022/01/18
acute lung injury
STING
vascular endothelial cells
inflammatory cytokines
chemokines
chemotaxis
Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 224, 页码: 14
作者:
He, Yu-Long
;
Chen, Meng-Ting
;
Wang, Ting
;
Zhang, Ming-Ming
;
Li, Ying-Xia
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/11/04
Type 2 diabetes mellitus
Dual FABP4/5 inhibitors
Anti-lipolytic and anti-inflammatory effects
Metabolic stability
Anti-diabetic activities
Genetically-engineered "all-in-one" vaccine platform for cancer immunotherapy
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 11, 页码: 3622-3635
作者:
Wu, Aihua
;
Chen, Yingzhi
;
Wang, Hairui
;
Chang, Ya
;
Zhang, Meng
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/01/18
Trichosanthin
Legumain
TRP2
Transcutaneous immunization
Adjuvant
Cancer vaccine
Protein engineering
Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13
作者:
Meng, Xiang-Dong
;
Gao, Li-Xin
;
Wang, Zhi-Jia
;
Feng, Bo
;
Zhang, Chun
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2021/12/01
2,5-diphenyl-1,3,4-oxadiazole derivatives
SHP2
Inhibitors
Structure-activity relationships (SAR)
Disulfiram-loaded lactoferrin nanoparticles for treating inflammatory diseases
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 卷号: 42, 期号: 11, 页码: 1913-1920
作者:
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/03/21
disulfiram
lactoferrin
macrophage-targeting delivery
sepsis
ulcerative colitis
pyroptosis
inflammation
Dynamics of Post-Translational Modification Inspires Drug Design in the Kinase Family
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15111-15125
作者:
Zhang, Huimin
;
He, Jixiao
;
Hu, Guang
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2022/01/04
Structural characteristics of Heparan sulfate required for the binding with the virus processing Enzyme Furin
期刊论文
OAI收割
GLYCOCONJUGATE JOURNAL, 2021, 页码: 11
作者:
Zeng, Jiaxin
;
Meng, Yuan
;
Chen, Shi-Yi
;
Zhao, Gaofeng
;
Wang, Lianchun
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2021/12/01
Furin
Heparan sulfate
Heparin
Virus infection
Carbohydrate-protein interaction
Recombinant cancer nanovaccine for targeting tumor-associated macrophage and remodeling tumor microenvironment
期刊论文
OAI收割
NANO TODAY, 2021, 卷号: 40, 页码: 14
作者:
Tang, Yisi
;
Fan, Wufa
;
Chen, Guihua
;
Zhang, Meng
;
Tang, Xueping
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/12/01
Cancer therapeutic vaccine
Legumain
Tumor-associated macrophage
Trichosanthin
Liposome
Adjuvant