机构

• 上海药物研究所 [50]

采集方式

• OAI收割 [50]

内容类型

• 期刊论文 [49]
• 会议论文 [1]

发表日期

• 2023 [2]
• 2022 [3]
• 2021 [5]
• 2020 [5]
• 2019 [3]
• 2018 [6]
• 更多

学科主题

筛选

浏览/检索结果: 共50条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764 作者:  Liu, Yingqiang;  Zhan, Zhengsheng;  Kang, Zhuang;  Li, Mengyuan;  Lv, Yongcong   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/01/26 Small molecule inhibitor  Tumor microenvironment  Immune-checkpoint  immune-deficient mouse models  including temozolomide (TMZ) insensitive tumors. Notably   Fine-tuning Bacterial Cyclic di-AMP Production for Durable Antitumor Effects Through the Activation of the STING Pathway 期刊论文  OAI收割 RESEARCH, 2023, 卷号: 6, 页码: 15 作者:  Jiang, Yu;  Li, Xiyuan;  Qian, Fenghui;  Sun, Bingbing;  Wang, Xiyuan   |  收藏  |  浏览/下载：24/0  |  提交时间：2023/10/17 Discovery of a potent and selective proteolysis targeting chimera (PROTAC) degrader of NSD3 histone methyltransferase 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 239, 页码: 18 作者:  Sun, Yaoliang;  Zhang, Ying;  Chen, Xiaoai;  Yu, Aisong;  Du, Wenhao   |  收藏  |  浏览/下载：41/0  |  提交时间：2022/08/30 NSD3  PROTAC  Degrader  Methyltransferase   Structure-Based of a Series of NSD2-PWWP1 Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 13, 页码: 9459-9477 作者:  Li, Na;  Yang, Hong;  Liu, Ke;  Zhou, Liwei;  Huang, Yuting   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/03/21 SAF-248,a novel PI3Kδ-selective inhibitor,potently suppresses the growth of diffuse large B-cell lymphoma 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 1, 页码: 209 作者:  Zhang Xi;  Duan Yuting;  Wang Yi   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/05/22 PI3K6  PI3K/AKT/mTOR  diffuse large B-cell lymphoma  resistance  combination therapy   Design, Synthesis, and Pharmacological Evaluation of Biaryl-Containing PD-1/PD-L1 Interaction Inhibitors Bearing a Unique Difluoromethyleneoxy Linkage 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 22, 页码: 16687-16702 作者:  Song, Zilan;  Liu, Bo;  Peng, Xia;  Gu, Wangting;  Sun, Yiming   |  收藏  |  浏览/下载：15/0  |  提交时间：2022/06/15 Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance (vol 19, 90, 2020) 期刊论文  OAI收割 MOLECULAR CANCER, 2021, 卷号: 20, 期号: 1, 页码: 1 作者:  Zhang, Tao;  Qu, Rong;  Chan, Shingpan;  Lai, Mengzhen;  Tong, Linjiang   |  收藏  |  浏览/下载：87/0  |  提交时间：2021/11/04 Correction to: Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance 期刊论文  OAI收割 Molecular Cancer, 2021, 卷号: 20, 期号: 1 作者:  Zhang,Tao;  Qu,Rong;  Chan,Shingpan;  Lai,Mengzhen;  Tong,Linjiang   |  收藏  |  浏览/下载：61/0  |  提交时间：2021/11/04 Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18 作者:  Xu, Dandan;  Sun, Deqiao;  Wang, Wei;  Peng, Xia;  Zhan, Zhengsheng   |  收藏  |  浏览/下载：38/0  |  提交时间：2021/08/17 Axl  Cancer  Inhibitor  Pyrrolo[2,3-d]pyrimidine   A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia 期刊论文  OAI收割 Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1 作者:  Xiao,Shifu;  Chan,Piu;  Wang,Tao;  Hong,Zhen;  Wang,Shuzhen   |  收藏  |  浏览/下载：84/0  |  提交时间：2021/05/24 Sodium oligomannate  Efficacy  Safety  Alzheimer’s disease  Clinical trial