中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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  • 上海药物研究所 [225]
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Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses 期刊论文  OAI收割
NATURE CHEMICAL BIOLOGY, 2024, 页码: 29
作者:  
Zhou, Xiaoyu;  Zhao, Cheng;  Xu, Haiyan;  Xu, Yixiang;  Zhan, Li
  |  收藏  |  浏览/下载:13/0  |  提交时间:2024/03/25
Discovery and exploration of novel somatostatin receptor subtype 5 (SSTR5) antagonists for the treatment of cholesterol gallstones 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 16
作者:  
Han, Fanghui;  Zhao, Tingting;  Zhang, Yanglong;  Yun, Ying;  Xu, Yuanyuan
  |  收藏  |  浏览/下载:2/0  |  提交时间:2024/02/19
A novel capsid-XL32-derived adeno-associated virus serotype prompts retinal tropism and ameliorates choroidal neovascularization 期刊论文  OAI收割
BIOMATERIALS, 2024, 卷号: 304, 页码: 13
作者:  
Luo, Lin-Lin;  Xu, Jie;  Wang, Bing-Qiao;  Chen, Chen;  Chen, Xi
  |  收藏  |  浏览/下载:9/0  |  提交时间:2024/01/26
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:  
Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan
  |  收藏  |  浏览/下载:11/0  |  提交时间:2023/12/11
Total synthesis of (±)-villosin C and (±)-teuvincenone B 期刊论文  OAI收割
ORGANIC CHEMISTRY FRONTIERS, 2023, 页码: 5
作者:  
Zhou, Jin-Xin;  Yan, Ming-Jie;  Shi, Xiao-Yu;  Wang, Yue-Qi;  Shen, Hong-Yan
  |  收藏  |  浏览/下载:22/0  |  提交时间:2024/01/16
The claustrum-prelimbic cortex circuit through dynorphin/κ-opioid receptor signaling underlies depression-like behaviors associated with social stress etiology 期刊论文  OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 17
作者:  
Wang, Yu-Jun;  Zan, Gui-Ying;  Xu, Cenglin;  Li, Xue-Ping;  Shu, Xuelian
  |  收藏  |  浏览/下载:12/0  |  提交时间:2024/02/19
Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR plus Human Prostate Cancer 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 18, 页码: 13280-13303
作者:  
Xiang, Weiguo;  Zhao, Lijie;  Han, Xin;  Xu, Tianfeng;  Kregel, Steven
  |  收藏  |  浏览/下载:8/0  |  提交时间:2023/12/08
Discovery and Mechanism Study of SARS-CoV-2 3C-like Protease Inhibitors with a New Reactive Group 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 18
作者:  
Ren, Pengxuan;  Li, Hui;  Nie, Tianqing;  Jian, Xiaoqin;  Yu, Changyue
  |  收藏  |  浏览/下载:9/0  |  提交时间:2023/10/17
Ligand recognition and G protein coupling of the human itch receptor MRGPRX1 期刊论文  OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 12
作者:  
Guo, Lulu;  Zhang, Yumu;  Fang, Guoxing;  Tie, Lu;  Zhuang, Yuming
  |  收藏  |  浏览/下载:20/0  |  提交时间:2024/01/16
Discovery, SAR Study of GST Inhibitors from a Novel Quinazolin-4(1H)-one Focused DNA-Encoded Library 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 15
作者:  
Wen, Xin;  Zhang, Minmin;  Duan, Zhiqiang;  Suo, Yanrui;  Lu, Weiwei
  |  收藏  |  浏览/下载:30/0  |  提交时间:2023/10/17