中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [6]
采集方式
OAI收割 [6]
内容类型
期刊论文 [6]
发表日期
2023 [1]
2022 [1]
2015 [1]
2014 [3]
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专题:上海药物研究所
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Exploration of novel four-membered-heterocycle constructed peptidyl proteasome inhibitors with improved metabolic stability for cancer treatment
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 138, 页码: 22
作者:
Wang, Hanlin
;
Wu, Zhaoxiao
;
Cao, Yu
;
Gao, Lixin
;
Shao, Jiaan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/10/17
Metabolic stability
Four-membered heterocycles
Proteasome inhibitors
Multiple myeloma
Metabolism guided optimization of peptidomimetics as non-covalent proteasome inhibitors for cancer treatment
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 233, 页码: 18
作者:
Cao, Yu
;
Tu, Yutong
;
Fu, Liping
;
Yu, Qian
;
Gao, Lixin
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/06/15
Metabolism
Design
Proteasome inhibitors
Non-covalent
Multiple myeloma
Disruption of the unfolded protein response (UPR) by lead compound selectively suppresses cancer cell growth
期刊论文
OAI收割
CANCER LETTERS, 2015, 卷号: 360, 期号: 2, 页码: 257-268
作者:
Huang, Hejing
;
Liu, Huanan
;
Liu, Changmei
;
Fan, Lixia
;
Zhang, Xinwen
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Selective cancer therapy
Unfolded protein response
2DG
UPR disrupter
Design, Synthesis and Biological Evaluation of Peptidyl Epoxyketone Proteasome Inhibitors Composed of beta-amino Acids
期刊论文
OAI收割
CHEMICAL BIOLOGY & DRUG DESIGN, 2014, 卷号: 84, 期号: 5, 页码: 497-504
作者:
Zhang, Jiankang
;
Han, Mengmeng
;
Ma, Xiaodong
;
Xu, Lei
;
Cao, Jiayi
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
anti-cancer
di- and tripeptides
epoxyketone
proteasome inhibitors
-amino acid
Design, synthesis and biological evaluation of thienopyridinones as Chk1 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 17, 页码: 4882-4892
作者:
Song, Pinrao
;
Peng, Peng
;
Han, Mengmeng
;
Cao, Xianchao
;
Ma, Xiaodong
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Chk1 inhibitor
Thienopyridinones
Antitumor
Cell synergy
Design, synthesis and biological evaluation of novel tripeptidyl epoxyketone derivatives constructed from beta-amino acid as proteasome inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 11, 页码: 2955-2965
作者:
Zhang, Jiankang
;
Cao, Jiayi
;
Xu, Lei
;
Zhou, Yubo
;
Liu, Tao
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/01/08
Proteasome inhibitors
beta-Amino acid
Epoxyketone
Anti-cancer
Drug design
SARs