机构

• 上海药物研究所 [25]

采集方式

• OAI收割 [25]

内容类型

• 期刊论文 [25]

发表日期

• 2024 [1]
• 2023 [2]
• 2021 [2]
• 2020 [3]
• 2019 [4]
• 2018 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共25条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of hematopoietic progenitor kinase 1 inhibitors using machine learning-based screening and free energy perturbation 期刊论文  OAI收割 JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2024, 页码: 13 作者:  Feng, Dazhi;  Liu, Bo;  Chen, Zhiwei;  Xu, Jinyi;  Geng, Meiyu   |  收藏  |  浏览/下载：25/0  |  提交时间：2024/02/27 HPK1 inhibitor  machine learning  virtual screening  free energy perturbation  structural modification   Design, synthesis and pharmacological evaluation of 2,3-dihydrobenzo-furan IRAK4 inhibitors for the treatment of diffuse large B-cell lymphoma 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 16 作者:  Chen, Yun;  Ning, Yi;  Chen, Zhiwei;  Xue, Yaping;  Wu, Qingyun   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 Apoptosis  Diffuse large B-Cell lymphoma  Interleukin-1 receptor associated kinase 4  Structure-based drug design  2  3-Dihydrobenzofuran   ETCM v2.0: An update with comprehensive resource and rich annotations for traditional Chinese medicine 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2559-2571 作者:  Zhang, Yanqiong;  Li, Xin;  Shi, Yulong;  Chen, Tong;  Xu, Zhijian   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/10/17 Traditional Chinese medicine  Database  Target identification  Network visualization  New drug research and development  Molecular mechanism  Quality marker  Drug repurposing   A proteomic and phosphoproteomic landscape of KRAS mutant cancers identifies combination therapies 期刊论文  OAI收割 MOLECULAR CELL, 2021, 卷号: 81, 期号: 19, 页码: 4076-+ 作者:  Liu, Zhiwei;  Liu, Yingluo;  Qian, Lili;  Jiang, Shangwen;  Gai, Xiameng   |  收藏  |  浏览/下载：60/0  |  提交时间：2021/12/01 Global identification of phospho-dependent SCF substrates reveals a FBXO22 phosphodegron and an ERK-FBXO22-BAG3 axis in tumorigenesis 期刊论文  OAI收割 CELL DEATH AND DIFFERENTIATION, 2021, 页码: 13 作者:  Liu, Ping;  Cong, Xiaoji;  Liao, Shengjie;  Jia, Xinglong;  Wang, Xiaomin   |  收藏  |  浏览/下载：42/0  |  提交时间：2021/08/17 Original Pharmacodynamic and pharmacokinetic effects of S086, a novel angiotensin receptor neprilysin inhibitor 期刊论文  OAI收割 BIOMEDICINE & PHARMACOTHERAPY, 2020, 卷号: 129, 页码: 10 作者:  Sun, Jingchao;  Xu, Wenjie;  Hua, Huaijie;  Xiao, Ying;  Chen, Xiaoyan   |  收藏  |  浏览/下载：21/0  |  提交时间：2020/12/24 Angiotensin receptor-NEP inhibitor  Heart failure  Neprilysin inhibitor  Angiotensin receptor blocker   Cryo-EM Structure of the Human Cannabinoid Receptor CB2-G(i) Signaling Complex 期刊论文  OAI收割 CELL, 2020, 卷号: 180, 期号: 4, 页码: 645-+ 作者:  Xing, Changrui;  Zhuang, Youwen;  Xu, Ting-Hai;  Feng, Zhiwei;  Zhou, X. Edward   |  收藏  |  浏览/下载：35/0  |  提交时间：2020/07/01 The Nonclinical Pharmacokinetics and Prediction of Human Pharmacokinetics of SPH3127, a Novel Direct Renin Inhibitor 期刊论文  OAI收割 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 2020, 卷号: 45, 期号: 1, 页码: 15-26 作者:  Zhang, Leduo;  Mao, Yu;  Gao, Zhiwei;  Chen, Xiaoyan;  Li, Xin   |  收藏  |  浏览/下载：19/0  |  提交时间：2020/07/01 SCFFBXW7/GSK3 beta-Mediated GFI1 Degradation Suppresses Proliferation of Gastric Cancer Cells 期刊论文  OAI收割 CANCER RESEARCH, 2019, 卷号: 79, 期号: 17, 页码: 4387-4398 作者:  Kuai, Xiaoling;  Li, Long;  Chen, Ran;  Wang, Kangjunjie;  Chen, Min   |  收藏  |  浏览/下载：29/0  |  提交时间：2020/07/01 Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia 期刊论文  OAI收割 CANCER CELL, 2019, 卷号: 35, 期号: 4, 页码: 677-+ 作者:     |  收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01