机构

• 上海药物研究所 [20]
• 合肥物质科学研究院 [5]
• 数学与系统科学研究院 [1]
• 西北高原生物研究所 [1]
• 新疆理化技术研究所 [1]
• 自动化研究所 [1]
• 更多

采集方式

• OAI收割 [33]

内容类型

• 期刊论文 [33]

发表日期

• 2023 [5]
• 2022 [6]
• 2021 [4]
• 2020 [6]
• 2019 [2]
• 2018 [2]
• 更多

学科主题

• Research &... [1]

筛选

浏览/检索结果: 共33条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 14 作者:  Liu, Jiayuan;  Zhang, Xianglei;  Chen, Guofeng;  Shao, Qiang;  Zou, Yi   |  收藏  |  浏览/下载：18/0  |  提交时间：2024/01/16 Phosphodiesterase-4 (PDE4)  PDE5  Inhibitor  Drug repurposing  Crystal structure  Structure -guided optimization   Repurposing of Rutan showed effective treatment for COVID-19 disease 期刊论文  OAI收割 FRONTIERS IN MEDICINE, 2023, 卷号: 10, 页码: 13 作者:  Salikhov, Shavkat I.;  Abdurakhmonov, Ibrokhim Y.;  Oshchepkova, Yuliya I.;  Ziyavitdinov, Jamolitdin F.;  Berdiev, Nodir Sh.   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/01/26 COVID-19  SARS-CoV-2  3CLpro  RdRp  Rhus coriaria  Rutan  clinical trial   MEDIATE-Molecular DockIng at homE: Turning collaborative simulations into therapeutic solutions 期刊论文  OAI收割 EXPERT OPINION ON DRUG DISCOVERY, 2023, 页码: 13 作者:  Vistoli, Giulio;  Manelfi, Candida;  Talarico, Carmine   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/10/17 Collaborative computing  virtual screening  docking simulations  drug repurposing  SARS-CoV-2  artificial intelligence   ETCM v2.0: An update with comprehensive resource and rich annotations for traditional Chinese medicine 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2559-2571 作者:  Zhang, Yanqiong;  Li, Xin;  Shi, Yulong;  Chen, Tong;  Xu, Zhijian   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/10/17 Traditional Chinese medicine  Database  Target identification  Network visualization  New drug research and development  Molecular mechanism  Quality marker  Drug repurposing   Discovery, synthesis and mechanism study of 2,3,5-substituted [1,2,4]-thiadiazoles as covalent inhibitors targeting 3C-Like protease of SARS-CoV-2 期刊论文  OAI收割 European journal of medicinal chemistry, 2023, 卷号: 249, 页码: 115129 作者:  Ren, Pengxuan;  Yu, Changyue;  Zhang, Ruxue;  Nie, Tianqing;  Hu, Qiaoyu   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/03/26 Repurposing of the FGFR inhibitor AZD4547 as a potent inhibitor of necroptosis by selectively targeting RIPK1 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022 作者:  Wang, Zuo-wei;  Zou, Feng-ming;  Wang, Ao-li;  Yang, Jing;  Jin, Rui   |  收藏  |  浏览/下载：30/0  |  提交时间：2022/12/22 AZD4547  RIPK1  inhibitors  SIRS model  anti-necroptosis   Novel niclosamide-derived adjuvants elevating the efficacy of polymyxin B against MDR Pseudomonas aeruginosa DK2 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 236, 页码: 114318 作者:  Lu, Taotao;  Zheng, Xinyu;  Mao, Fei   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/03/21 Pseudomonas aeruginosa DK2  Polymyxin B  Niclosamide  Adjuvants  Drug repurposing   D3AI-CoV: a deep learning platform for predicting drug targets and for virtual screening against COVID-19 期刊论文  OAI收割 BRIEFINGS IN BIOINFORMATICS, 2022, 页码: 16 作者:  Yang, Yanqing;  Zhou, Deshan;  Zhang, Xinben;  Shi, Yulong;  Han, Jiaxin   |  收藏  |  浏览/下载：35/0  |  提交时间：2022/06/15 D3AI-CoV  COVID-19  deep learning  target prediction  virtual screening   Data science approaches to confronting the COVID-19 pandemic: a narrative review 期刊论文  OAI收割 PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES, 2022, 卷号: 380, 期号: 2214, 页码: 20 作者:  Zhang, Qingpeng;  Gao, Jianxi;  Wu, Joseph T.;  Cao, Zhidong;  Zeng, Daniel Dajun   |  收藏  |  浏览/下载：24/0  |  提交时间：2021/12/28 infectious disease  mathematical modelling  data science  big data  COVID-19   A deep learning method for repurposing antiviral drugs against new viruses via multi-view nonnegative matrix factorization and its application to SARS-CoV-2 期刊论文  OAI收割 BRIEFINGS IN BIOINFORMATICS, 2022, 卷号: 23, 期号: 1, 页码: 1-6 作者:  Su, XR (Su, Xiaorui) [1];  Hu, L (Hu, Lun) [1];  You, ZH (You, Zhuhong) [2];  Hu, PW (Hu, Pengwei) [1];  Wang, L (Wang, Lei) [3]   |  收藏  |  浏览/下载：73/0  |  提交时间：2022/05/06 SARS-CoV-2  drugrepositioning  constrained multi-view nonnegative matrix factorization  deeplearning  graphconvolutionalnetwork