中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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  • 上海药物研究所 [16]
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Identification and evaluation of a lipid-lowering small compound in preclinical models and in a Phase I trial 期刊论文  OAI收割
CELL METABOLISM, 2022, 卷号: 34, 期号: 5, 页码: 667-+
作者:  
Wang, Jiang;  Zhao, Jing;  Yan, Cong;  Xi, Cong;  Wu, Chenglin
  |  收藏  |  浏览/下载:28/0  |  提交时间:2022/08/16
Global identification of phospho-dependent SCF substrates reveals a FBXO22 phosphodegron and an ERK-FBXO22-BAG3 axis in tumorigenesis 期刊论文  OAI收割
CELL DEATH AND DIFFERENTIATION, 2021, 页码: 13
作者:  
Liu, Ping;  Cong, Xiaoji;  Liao, Shengjie;  Jia, Xinglong;  Wang, Xiaomin
  |  收藏  |  浏览/下载:42/0  |  提交时间:2021/08/17
A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia 期刊论文  OAI收割
Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1
作者:  
Xiao,Shifu;  Chan,Piu;  Wang,Tao;  Hong,Zhen;  Wang,Shuzhen
  |  收藏  |  浏览/下载:83/0  |  提交时间:2021/05/24
23,24-Dihydrocucurbitacin B promotes lipid clearance by dual transcriptional regulation of LDLR and PCSK9 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 327-335
作者:  
Li, Hui-hui;  Li, Jun;  Zhang, Xian-jing;  Li, Jiao-meng;  Xi, Cong
  |  收藏  |  浏览/下载:25/0  |  提交时间:2020/07/01
A complex structure of arrestin-2 bound to a G protein-coupled receptor 期刊论文  OAI收割
CELL RESEARCH, 2019, 卷号: 29, 期号: 12, 页码: 971-983
作者:  
Yin, Wanchao;  Li, Zhihai;  Jin, Mingliang;  Yin, Yu-Ling;  de Waal, Parker W.
  |  收藏  |  浏览/下载:59/0  |  提交时间:2020/07/01
Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1216-1230
作者:  
Wu, Chenglin;  Xi, Cong;  Tong, Junhua;  Zhao, Jing;  Jiang, Hualiang
  |  收藏  |  浏览/下载:43/0  |  提交时间:2020/07/01
designsynthesisandbiologicalevaluationofnoveltetrahydroprotoberberinederivativesthpbsasproproteinconvertasesubtilisinkexintype9pcsk9modulatorsforthetreatmentofhyperlipidemia 期刊论文  OAI收割
actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 6, 页码: 1216
作者:  
Wu Chenglin;  Xi Cong;  Tong Junhua;  Zhao Jing;  Jiang Hualiang
  |  收藏  |  浏览/下载:8/0  |  提交时间:2020/07/01
acomplexstructureofarrestin2boundtoagproteincoupledreceptor 期刊论文  OAI收割
cellresearch, 2019, 卷号: 29, 期号: 12, 页码: 971
作者:  
Yin Wanchao;  Li Zhihai;  Jin Mingliang;  Yin Yuling;  De Waal Parker W
  |  收藏  |  浏览/下载:19/0  |  提交时间:2020/07/01
7 beta-Methyl substituent is a structural locus associated with activity cliff for nepenthone analogues 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 14, 页码: 4254-4263
作者:  
Sun, Hui-jiao;  Wang, Yu-hua;  Yuan, Cong-min;  Kong, Ling-hui;  Xu, Xue-jun
  |  收藏  |  浏览/下载:79/0  |  提交时间:2019/01/08
Docetaxel-loaded solid lipid nanoparticles as a basis for a targeted and dose-sparing personalized breast cancer treatment strategy Reply 期刊论文  OAI收割
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2015, 卷号: 10, 页码: 2420-2421
作者:  
Yuan, Qing;  Han, Jing;  Cong, Wenshu;  Ge, Ying
  |  收藏  |  浏览/下载:9/0  |  提交时间:2019/01/08