中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [16]
采集方式
OAI收割 [16]
内容类型
期刊论文 [16]
发表日期
2022 [1]
2021 [2]
2020 [1]
2019 [4]
2018 [1]
2015 [1]
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浏览/检索结果:
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专题:上海药物研究所
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Identification and evaluation of a lipid-lowering small compound in preclinical models and in a Phase I trial
期刊论文
OAI收割
CELL METABOLISM, 2022, 卷号: 34, 期号: 5, 页码: 667-+
作者:
Wang, Jiang
;
Zhao, Jing
;
Yan, Cong
;
Xi, Cong
;
Wu, Chenglin
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/08/16
Global identification of phospho-dependent SCF substrates reveals a FBXO22 phosphodegron and an ERK-FBXO22-BAG3 axis in tumorigenesis
期刊论文
OAI收割
CELL DEATH AND DIFFERENTIATION, 2021, 页码: 13
作者:
Liu, Ping
;
Cong, Xiaoji
;
Liao, Shengjie
;
Jia, Xinglong
;
Wang, Xiaomin
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/08/17
A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia
期刊论文
OAI收割
Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1
作者:
Xiao,Shifu
;
Chan,Piu
;
Wang,Tao
;
Hong,Zhen
;
Wang,Shuzhen
  |  
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2021/05/24
Sodium oligomannate
Efficacy
Safety
Alzheimer’s disease
Clinical trial
23,24-Dihydrocucurbitacin B promotes lipid clearance by dual transcriptional regulation of LDLR and PCSK9
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 327-335
作者:
Li, Hui-hui
;
Li, Jun
;
Zhang, Xian-jing
;
Li, Jiao-meng
;
Xi, Cong
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
23,24-dihydrocucurbitacin B
lipid-lowering agent
LDLR
PCSK9
HNF1 alpha
SREBP2
A complex structure of arrestin-2 bound to a G protein-coupled receptor
期刊论文
OAI收割
CELL RESEARCH, 2019, 卷号: 29, 期号: 12, 页码: 971-983
作者:
Yin, Wanchao
;
Li, Zhihai
;
Jin, Mingliang
;
Yin, Yu-Ling
;
de Waal, Parker W.
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2020/07/01
Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1216-1230
作者:
Wu, Chenglin
;
Xi, Cong
;
Tong, Junhua
;
Zhao, Jing
;
Jiang, Hualiang
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/07/01
PCSK9
Tetrahydroprotoberberine derivatives
Low-density lipoprotein cholesterol
Lipid-lowering
PCSK9 expression
Low-density lipoprotein receptor
Total cholesterol
Hyperlipidemia hamster
designsynthesisandbiologicalevaluationofnoveltetrahydroprotoberberinederivativesthpbsasproproteinconvertasesubtilisinkexintype9pcsk9modulatorsforthetreatmentofhyperlipidemia
期刊论文
OAI收割
actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 6, 页码: 1216
作者:
Wu Chenglin
;
Xi Cong
;
Tong Junhua
;
Zhao Jing
;
Jiang Hualiang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/07/01
DOPAMINE D-1
BERBERINE
EXPRESSION
INHIBITORS
IDENTIFICATION
CHOLESTEROL
MUTATIONS
LDLR
PCSK9
Tetrahydroprotoberberine derivatives
Low-density lipoprotein cholesterol
Lipid-lowering
PCSK9 expression
Low-density lipoprotein receptor
Total cholesterol
Hyperlipidemia hamster
acomplexstructureofarrestin2boundtoagproteincoupledreceptor
期刊论文
OAI收割
cellresearch, 2019, 卷号: 29, 期号: 12, 页码: 971
作者:
Yin Wanchao
;
Li Zhihai
;
Jin Mingliang
;
Yin Yuling
;
De Waal Parker W
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
NEUROTENSIN
VISUALIZATION
RECRUITMENT
AGONIST
ML314
7 beta-Methyl substituent is a structural locus associated with activity cliff for nepenthone analogues
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 14, 页码: 4254-4263
作者:
Sun, Hui-jiao
;
Wang, Yu-hua
;
Yuan, Cong-min
;
Kong, Ling-hui
;
Xu, Xue-jun
  |  
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2019/01/08
7 beta-Methyl-nepenthone analogues
KOR ligands
Concept of hybridization
Opioid receptor binding and functional activities
Docetaxel-loaded solid lipid nanoparticles as a basis for a targeted and dose-sparing personalized breast cancer treatment strategy Reply
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2015, 卷号: 10, 页码: 2420-2421
作者:
Yuan, Qing
;
Han, Jing
;
Cong, Wenshu
;
Ge, Ying
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/01/08