中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [49]
采集方式
OAI收割 [49]
内容类型
期刊论文 [48]
会议论文 [1]
发表日期
2023 [1]
2022 [3]
2021 [6]
2020 [3]
2019 [1]
2018 [5]
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专题:上海药物研究所
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Two New Protolimonoids from the Chinese Mangrove Xylocarpus granatum Koenig
期刊论文
OAI收割
CHEMISTRY & BIODIVERSITY, 2023, 页码: 5
作者:
Su, Ming-Zhi
;
Zhou, Zhen-Fang
;
Guo, Yue-Wei
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/10/17
Xylocarpus granatum
mangrove plant
protolimonoid
apotirucallane
glabretal
Structural basis for the tethered peptide activation of adhesion GPCRs
期刊论文
OAI收割
NATURE, 2022, 页码: 41
作者:
Ping, Yu-Qi
;
Xiao, Peng
;
Yang, Fan
;
Zhao, Ru-Jia
;
Guo, Sheng-Chao
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/06/15
Absorption, distribution, metabolism, and excretion of [C-14]TPN729 after oral administration to rats
期刊论文
OAI收割
XENOBIOTICA, 2022, 页码: 12
作者:
Cheng, Huan
;
Yu, Jinghua
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/06/15
TPN729
[C-14]TPN729
mass balance
tissue distribution
metabolism
Atractylenolide III ameliorates Non-Alcoholic Fatty Liver Disease by activating Hepatic Adiponectin Receptor 1-Mediated AMPK Pathway
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2022, 卷号: 18, 期号: 4, 页码: 1594-1611
作者:
Li, Qian
;
Tan, Jia-Xin
;
He, Yong
;
Bai, Fang
;
Li, Shi-Wei
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/06/15
ATL III
AdipoR1
oxidative stress
inflammation
AMPK
SIRT1
Effects of Food on the Pharmacokinetic Properties and Mass Balance of Henagliflozin in Healthy Male Volunteers
期刊论文
OAI收割
CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 9, 页码: E264-E273
作者:
Chen, Zhen-dong
;
Chen, Qian
;
Zhu, Yun-ting
;
Zhang, Yi-fan
;
Zhan, Yan
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2022/01/04
henagliflozin
food effects
mass balance
pharmacokinetics
SGLT-2 inhibitor
Survival-Assured Liver Injury Preconditioning (SALIC) Enables Robust Expansion of Human Hepatocytes in Fah(-/-)Rag2(-/-)IL2rg(-/-) Rats
期刊论文
OAI收割
ADVANCED SCIENCE, 2021, 页码: 14
作者:
Zhang, Ludi
;
Ge, Jian-Yun
;
Zheng, Yun-Wen
;
Sun, Zhen
;
Wang, Chenhua
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/11/04
bioreactor
humanized liver
liver xeno-repopulation
pharmacological study
Furmonertinib (Alflutinib, AST2818) is a potential positive control drug comparable to rifampin for evaluation of CYP3A4 induction in sandwich-cultured primary human hepatocytes
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Wu, Ya-li
;
Xue, Ya-ru
;
Guo, Zi-tao
;
Chen, Zhen-dong
;
Ge, Xin-yu
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/08/17
furmonertinib (alflutinib
AST2818)
quantitative proteomics
sandwich-cultured human hepatocytes
Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Meng, Jian
;
Zhang, Hua
;
Bao, Jing-jing
;
Chen, Zhen-dong
;
Liu, Xiao-yun
  |  
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/06/11
metabolism
mass balance
distribution
covalent binding
furmonertinib
Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Meng, Jian
;
Zhang, Hua
;
Bao, Jing-jing
;
Chen, Zhen-dong
;
Liu, Xiao-yun
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2021/06/11
metabolism
mass balance
distribution
covalent binding
furmonertinib
Aristolochic acid I promoted clonal expansion but did not induce hepatocellular carcinoma in adult rats
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Liu, Yong-zhen
;
Lu, Heng-lei
;
Qi, Xin-ming
;
Xing, Guo-zhen
;
Wang, Xin
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
aristolochic acid I
glutathione S-transferase placental form-positive foci
clonal expansion
hepatocellular carcinoma
medium-term rat liver bioassay
DNA adducts