中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [11]
采集方式
OAI收割 [11]
内容类型
期刊论文 [11]
发表日期
2023 [1]
2022 [2]
2021 [3]
2020 [1]
2019 [1]
2018 [1]
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专题:上海药物研究所
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Discovery of HCD3514 as a potent EGFR inhibitor against C797S mutation in vitro and in vivo
期刊论文
OAI收割
JOURNAL OF CANCER, 2023, 卷号: 14, 期号: 1, 页码: 152-162
作者:
Lai, Mengzhen
;
Zhang, Tao
;
Chen, Hao
;
Song, Peiran
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2023/04/10
fourth-generation EGFR inhibitor
EGFRC797S mutation
NSCLC
drug resistance
small molecular inhibitor
Structure-Based of a Series of NSD2-PWWP1 Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 13, 页码: 9459-9477
作者:
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/03/21
Withaphysalins from Medicinal and Edible Physalis minima and Their Anti-inflammatory Activities
期刊论文
OAI收割
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2022, 卷号: 70, 期号: 18, 页码: 5595-5609
作者:
Hu, Bintao
;
Li, Han
;
Tang, Chunping
;
Ke, Chang-Qiang
;
Geng, Meiyu
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/08/16
Physalis minima
withaphysalin
14?-OH
anti-inflammatory
NF-?B
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
OAI收割
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
  |  
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance (vol 19, 90, 2020)
期刊论文
OAI收割
MOLECULAR CANCER, 2021, 卷号: 20, 期号: 1, 页码: 1
作者:
Zhang, Tao
;
Qu, Rong
;
Chan, Shingpan
;
Lai, Mengzhen
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2021/11/04
Correction to: Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
期刊论文
OAI收割
Molecular Cancer, 2021, 卷号: 20, 期号: 1
作者:
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2021/11/04
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
期刊论文
OAI收割
MOLECULAR CANCER, 2020, 卷号: 19, 期号: 1, 页码: 15
作者:
  |  
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2020/07/01
Non-small cell lung cancer (NSCLC)
EGFR T790M
Small-molecule inhibitor
Drug resistance
Ack1
Discovery of a novel third generation EGFR TKI and identification of its potential mechanism of resistance
期刊论文
OAI收割
CANCER RESEARCH, 2019, 卷号: 79, 期号: 13, 页码: 2
作者:
Zhang, Tao
;
Qu, Rong
;
Chen, Chengbin
;
Tong, Linjiang
;
Feng, Fang
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
identificationofcompoundd2923asanovelantitumoragenttargetingcsf1r
期刊论文
OAI收割
actapharmacologicasinica, 2018, 卷号: 039, 期号: 011, 页码: 1768
作者:
Liu Yingqiang
;
Wang Yanan
;
Lu Xiaoyun
;
Tong Linjiang
;
Li Yan
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
肿瘤组织
代理人
apoptosis
生长抑制率
复合
指向
鉴定
巨噬细胞
C5-substituted pyrido[2,3-d]pyrimidin-7-ones as highly specific kinase inhibitors targeting the clinical resistance-related EGFR(T790M) mutant
期刊论文
OAI收割
MEDCHEMCOMM, 2015, 卷号: 6, 期号: 9, 页码: 1693-1697
作者:
Xu, Tianfeng
;
Peng, Ting
;
Ren, Xiaomei
;
Zhang, Lianwen
;
Yu, Lei
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08