机构

• 上海药物研究所 [8]

采集方式

• OAI收割 [8]

内容类型

• 期刊论文 [8]

发表日期

• 2023 [2]
• 2022 [1]
• 2020 [2]
• 2018 [1]
• 2009 [2]

学科主题

筛选

浏览/检索结果: 共8条，第1-8条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 FMRP phosphorylation modulates neuronal translation through YTHDF1 期刊论文  OAI收割 MOLECULAR CELL, 2023, 卷号: 83, 期号: 23 作者:  Zou, Zhongyu;  Wei, Jiangbo;  Chen, Yantao;  Kang, Yunhee;  Shi, Hailing   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/03/27 Design, synthesis of novel benzimidazole derivatives as ENL inhibitors suppressing leukemia cells viability via downregulating the expression of MYC 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 14 作者:  Guo, Siqi;  Jia, Tongguan;  Xu, Xiaoming;  Yang, Feng;  Xiao, Senhao   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/04/10 ENL Inhibitor  YEATS domain  Histone lysine acetylation  Benzimidazole derivatives  Acute myeloid leukemia   Design and synthesis of novel benzimidazole-iminosugars linked a substituted phenyl group and their inhibitory activities against beta-glucosidase 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2022, 卷号: 127, 页码: 6 作者:  Liu, Xu;  Li, Fengxin;  Su, Lulu;  Wang, Mingchen;  Jia, Tongguan   |  收藏  |  浏览/下载：44/0  |  提交时间：2022/08/30 Benzimidazole-iminosugars  Glucosidase inhibitors  Suzuki coupling reaction  Inhibition type  Solvent-exposed region   Design, Synthesis, and Biological Activities of Novel Triazolothiadiazole Derivatives Linked with Amino Side Chain Containing Urea Group as DOT1L Inhibitors 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2020, 卷号: 40, 期号: 8, 页码: 2450-2459 作者:  Liu Na;  Guo Siqi;  Liu Junfang;  Chen Yantao;  Xu Xiaoming   |  收藏  |  浏览/下载：29/0  |  提交时间：2020/12/24 DOT1L inhibitor  triazolothiadiazole  triazolothiadiazine  nucleophilic substitution   Structural Modifications of the Triazolo-thiadiazole Derivatives as DOT1L Inhibitors and Their Activities 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2020, 卷号: 40, 期号: 5, 页码: 1345-1354 作者:  Xu Xiaoming;  Guo Siqi;  Zhang Jing;  Chen Yantao;  Kang Yaqing   |  收藏  |  浏览/下载：18/0  |  提交时间：2020/12/24 DOT1L inhibitor  ttriazolo-thiadiazole  structural modification  hydrophobic substituent  structure-activity analysis   Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral beta-lactam bridged combretastatin A-4 analogues as potent antitumor agents 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 144, 页码: 817-842 作者:  Zhou, Pengfei;  Liang, Yuru;  Zhang, Hao;  Jiang, Hao;  Feng, Kechang   |  收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08 1,4-Diaryl-2-azetidinone  Combretastatin A-4  Tubulin polymerization  Antitumor   C-X center dot center dot center dot H Contacts in Biomolecular Systems: How They Contribute to Protein-Ligand Binding Affinity 期刊论文  OAI收割 JOURNAL OF PHYSICAL CHEMISTRY B, 2009, 卷号: 113, 期号: 37, 页码: 12615-12621 作者:  Lu, Yunxiang;  Wang, Yong;  Xu, Zhijian;  Yan, Xiuhua;  Luo, Xiaoming   |  收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 Halogen Bonding-A Novel Interaction for Rational Drug Design? 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2009, 卷号: 52, 期号: 9, 页码: 2854-2862 作者:  Lu, Yunxiang;  Shi, Ting;  Wang, Yong;  Yang, Huaiyu;  Yan, Xiuhua   |  收藏  |  浏览/下载：6/0  |  提交时间：2019/01/08