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上海生物化学与细胞... [26]
上海药物研究所 [10]
上海神经科学研究所 [1]
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OAI收割 [38]
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期刊论文 [38]
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Biochemis... [38]
Biophysics [3]
Chemistry [2]
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学科主题:Biochemistry & Molecular Biology
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Crystal Structure of DNA Cytidine Deaminase ABOBEC3G Catalytic Deamination Domain Suggests a Binding Mode of Full-length Enzyme to Single-stranded DNA
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2015, 卷号: 290, 期号: 7, 页码: 4010-4021
作者:
Lu, XX
;
Zhang, TL
;
Xu, Z
;
Liu, SS
;
Zhao, B
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2015/07/22
Subdomain II of alpha-Isopropylmalate Synthase Is Essential for Activity INFERRING A MECHANISM OF FEEDBACK INHIBITION
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2014, 卷号: 289, 期号: 40, 页码: 27966-27978
作者:
Zhang, ZL
;
Wu, J
;
Lin, W
;
Wang, J
;
Yan, H
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2015/07/22
Allosteric Regulation
Cooperativity
Enzyme Catalysis
Enzyme Structure
Protein Conformation
Catalytic Module
Feedback Inhibition
Structural insights into the functions of the FANCM-FAAP24 complex in DNA repair
期刊论文
OAI收割
NUCLEIC ACIDS RESEARCH, 2013, 卷号: 41, 期号: 22, 页码: 10573-10583
作者:
Yang, H
;
Zhang, TL
;
Tao, Y
;
Wang, F
;
Tong, L
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  |  
浏览/下载:16/0
  |  
提交时间:2015/07/22
Structures of trans-2-enoyl-00A reductases from Clostridium acelobutylicum and Treponema denticola: insights into the substrate specificity and the catalytic mechanism
期刊论文
OAI收割
BIOCHEMICAL JOURNAL, 2013, 卷号: 449, 期号: 1, 页码: 79-89
作者:
Hu, K
;
Zhao, M
;
Zhang, TL
;
Zha, MW
;
Zhong, C
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2015/07/22
biofuel
catalytic mechanism
crystal structure
reductase
substrate specificity
synthetic biology
Identification, Characterization, and Epitope Mapping of Human Monoclonal Antibody J19 That Specifically Recognizes Activated Integrin alpha(4)beta(7)
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 卷号: 287, 期号: 19, 页码: 15749-15759
作者:
Qi, JP
;
Zhang, K
;
Zhang, Q
;
Sun, Y
;
Fu, T
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2015/07/22
Crystal structures and kinetic studies of human Kappa class glutathione transferase provide insights into the catalytic mechanism
期刊论文
OAI收割
BIOCHEMICAL JOURNAL, 2011, 卷号: 439, 期号: 1, 页码: 215-225
作者:
Wang, B
;
Peng, YJ
;
Zhang, TL
;
Ding, JP
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2015/07/22
catalytic mechanism
conformational change
crystal structure
Kappa class glutathione transferase (GSTk)
kinetic measurement
substrate-binding pocket
Molecular basis of the inhibitor selectivity and insights into the feedback inhibition mechanism of citramalate synthase from Leptospira interrogans
期刊论文
OAI收割
BIOCHEMICAL JOURNAL, 2009, 卷号: 421, 期号: 1, 页码: 133-143
作者:
Zhang, P
;
Ma, J
;
Zhang, ZL
;
Zha, MW
;
Xu, H
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2015/07/22
allosteric regulation
crystal structure
feedback inhibition
mechanism
selectivity
A conserved hydrophobic core at Bcl-x(L) mediates its structural stability and binding affinity with BH3-domain peptide of pro-apoptotic protein
期刊论文
OAI收割
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2009, 卷号: 484, 期号: 1, 页码: 46-54
作者:
Feng, Y
;
Zhang, L
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2015/07/22
Bcl-x(L)
Hydrophobic core
Protein stability
Heterodimerization
Pore formation