Synthesis of Impurities of Pramipexole Dihydrochloride
文献类型：期刊论文
| 作者 | Hu, Tianwen1,3; Yang, Feipu1,3; Jiang, Tao1,3; Chen, Weiming2; Zhang, Jian2; Li, Jianfeng1 ; Jiang, Xiangrui1; Shen, Jingshan1
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| 刊名 | ORGANIC PROCESS RESEARCH & DEVELOPMENT
 |
| 出版日期 | 2016-11 |
| 卷号 | 20期号:11页码:1899-1905 |
| ISSN号 | 1083-6160 |
| 关键词 | pramipexole Mirapex impurities synthesis Mitsunobu reaction |
| DOI | 10.1021/acs.oprd.6b00182 |
| 文献子类 | Article |
| 英文摘要 | Three impurities of pramipexole dihydrochloride were synthesized, and the possible generation mechanisms and the preparation methods of some impurities were reviewed. The desired configuration at C7 of 3 was built by a Mitsunobu reaction. |
| WOS关键词 | RESTLESS LEGS SYNDROME ; AGONISTS |
| 资助项目 | Science and Technology Commission of Shanghai Municipality[14431905500] ; National Natural Science Foundation of China[81273366] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| 出版者 | AMER CHEMICAL SOC |
| WOS记录号 | WOS:000388430300004 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/275828]  |
| 专题 | 药物化学研究室 |
| 通讯作者 | Jiang, Xiangrui |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Drug Discovery & Design Ctr, CAS Key Lab Receptor Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China; 2.Topharman Shanghai Co Ltd, Shanghai 201209, Peoples R China 3.Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Hu, Tianwen,Yang, Feipu,Jiang, Tao,et al. Synthesis of Impurities of Pramipexole Dihydrochloride[J]. ORGANIC PROCESS RESEARCH & DEVELOPMENT,2016,20(11):1899-1905. |
| APA | Hu, Tianwen.,Yang, Feipu.,Jiang, Tao.,Chen, Weiming.,Zhang, Jian.,...&Shen, Jingshan.(2016).Synthesis of Impurities of Pramipexole Dihydrochloride.ORGANIC PROCESS RESEARCH & DEVELOPMENT,20(11),1899-1905. |
| MLA | Hu, Tianwen,et al."Synthesis of Impurities of Pramipexole Dihydrochloride".ORGANIC PROCESS RESEARCH & DEVELOPMENT 20.11(2016):1899-1905. |
入库方式： OAI收割
来源：上海药物研究所
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