Synthesis, characterization, and antitumor activities of new palladium(II) complexes with 1-(alkyldithiocarbonyl)imidazoles
文献类型：期刊论文
| 作者 | Hou, Xueling ; Li, Xiaobo; Hemit, Helimay; Aisa, Haji Akber
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| 刊名 | JOURNAL OF COORDINATION CHEMISTRY
 |
| 出版日期 | 2014 |
| 卷号 | 67期号:3页码:461-469 |
| 关键词 | Dithiocarbamate Palladium Imidazole Antitumor activity |
| ISSN号 | 0095-8972 |
| 通讯作者 | Hou, XL |
| 中文摘要 | Pd(II) complexes with imidazole linked to dithiocarbamate derivatives were synthesized by reacting 1-(alkyldithiocarbonyl)-imidazoles with PdCl2 in a 2:1molar ratio. The complexes were characterized by elemental analyses, FT-IR, and H-1 NMR. The single crystal structure of 4 shows that the ligand is chelated by nitrogens in imidazole, instead of sulfur, to palladium. All synthesized compounds were tested for in vitro anticancer activities. Compound 5 had better activities in the HL-60 cell line and twofold better activities in the HeLa cell line than that of cisplatin. |
| 收录类别 | SCI |
| 资助信息 | National Natural Science Foundation of ChinaCAS/SAFEA International Partnership Program for Creative Research Teams |
| 公开日期 | 2014-11-11 |
| 源URL | [http://ir.xjipc.cas.cn/handle/365002/3804]  |
| 专题 | 新疆理化技术研究所_省部共建新疆特有药用资源利用重点实验室 新疆理化技术研究所_资源化学研究室 |
| 作者单位 | Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Plant Resources & Chem Arid Zone, State Key Lab Basis Xinjiang Indigenous Med Plant, Urumqi, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hou, Xueling,Li, Xiaobo,Hemit, Helimay,et al. Synthesis, characterization, and antitumor activities of new palladium(II) complexes with 1-(alkyldithiocarbonyl)imidazoles[J]. JOURNAL OF COORDINATION CHEMISTRY,2014,67(3):461-469. |
| APA | Hou, Xueling,Li, Xiaobo,Hemit, Helimay,&Aisa, Haji Akber.(2014).Synthesis, characterization, and antitumor activities of new palladium(II) complexes with 1-(alkyldithiocarbonyl)imidazoles.JOURNAL OF COORDINATION CHEMISTRY,67(3),461-469. |
| MLA | Hou, Xueling,et al."Synthesis, characterization, and antitumor activities of new palladium(II) complexes with 1-(alkyldithiocarbonyl)imidazoles".JOURNAL OF COORDINATION CHEMISTRY 67.3(2014):461-469. |
入库方式： OAI收割
来源：新疆理化技术研究所
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