中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [15]
采集方式
OAI收割 [15]
内容类型
期刊论文 [15]
发表日期
2019 [15]
学科主题
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发表日期:2019
专题:上海药物研究所
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Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 15
作者:
Lu, Wenchao
;
Wang, Jun
;
Li, Yong
;
Tao, Hongru
;
Xiong, Huan
  |  
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2020/07/01
Hippo pathway
TEAD transcription factor
Covalent inhibitor
Palmitoylation inhibitor
A complex structure of arrestin-2 bound to a G protein-coupled receptor
期刊论文
OAI收割
CELL RESEARCH, 2019, 卷号: 29, 期号: 12, 页码: 971-983
作者:
Yin, Wanchao
;
Li, Zhihai
;
Jin, Mingliang
;
Yin, Yu-Ling
;
de Waal, Parker W.
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2020/07/01
Synthesis of Aryl Propionamide Scaffold Containing a Pentafluorosulfanyl Moiety as SARMs
期刊论文
OAI收割
MOLECULES, 2019, 卷号: 24, 期号: 23, 页码: 13
作者:
Shao, Pingxuan
;
Zhou, Yan
;
Yang, Dehua
;
Wang, Ming-Wei
;
Lu, Wei
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
pentafluorosulfanyl
aryl propionamide
androgen receptor
agonist
SARMs
YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 14
作者:
Shi, Yulin
;
Fan, Songqing
;
Wu, Mengge
;
Zuo, Zhixiang
;
Li, Xingyang
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
Integrating yeast chemical genomics and mammalian cell pathway analysis
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1245-1255
作者:
Zhou, Fu-lai
;
Li, Sheena C.
;
Zhu, Yue
;
Guo, Wan-jing
;
Shao, Li-jun
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
yeast
chemical genomics
tubulin cytoskeleton assembly
autophagy
Wnt/beta-catenin signaling pathway
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1193-1204
作者:
Zhou, Ting-ting
;
Zhao, Tong
;
Ma, Fei
;
Zhang, Yi-nan
;
Jiang, Jing
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
type 2 diabetes mellitus
hepatic gluconeogenesis
AMPK signaling pathway
(E)-3-(2-(quinoline-4-yl)vinyl)-1H-indol-6-ol (QVO)
4-[2-(1H-indol-3-yl)vinyl]quinoline (IVQ)
prodrug
Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 16, 页码: 7473-7488
作者:
Wang, Yulan
;
Dai, Yang
;
Wu, Xiaowei
;
Li, Fei
;
Liu, Bo
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/07/01
Identification of new NIK inhibitors by discriminatory analysis-based molecular docking and biological evaluation
期刊论文
OAI收割
ARCHIV DER PHARMAZIE, 2019, 卷号: 352, 期号: 7, 页码: 9
作者:
Cheng, Gang
;
Mei, Xiao-Bing
;
Yan, You-You
;
Chen, Jing
;
Zhang, Bo
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
antiproliferation activity
inhibitors
NF-kappa B inducing kinase
virtual screen
Identification of a USP9X Substrate NFX1-123 by SILAC-Based Quantitative Proteomics
期刊论文
OAI收割
JOURNAL OF PROTEOME RESEARCH, 2019, 卷号: 18, 期号: 6, 页码: 2654-2665
作者:
Chen, Xiangling
;
Lu, Dayun
;
Gao, Jing
;
Zhu, Hongwen
;
Zhou, Yanting
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
deubiquitinase
USP9X
NFX1-123
SILAC
quantitative proteomics
Identification of Glutaminyl Cyclase isoenzyme isoQC as a regulator of SIRP alpha-CD47 axis
期刊论文
OAI收割
CELL RESEARCH, 2019, 卷号: 29, 期号: 6, 页码: 502-505
作者:
Wu, Zhiqiang
;
Weng, Linjun
;
Zhang, Tengbo
;
Tian, Hongling
;
Fang, Lan
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01