机构

• 上海药物研究所 [13]

采集方式

• OAI收割 [13]

内容类型

• 期刊论文 [13]

发表日期

• 2020 [13]

学科主题

筛选

浏览/检索结果: 共13条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9 作者:  Dai, Meng-di;  Wang, Yue-liang;  Fan, Jun;  Dai, Yang;  Ji, Yin-chun   |  收藏  |  浏览/下载：69/0  |  提交时间：2021/05/24 receptor tyrosine kinase  FGFR inhibitor  DW14383  antitumor activity   An exosome-like programmable-bioactivating paclitaxel prodrug nanoplatform for enhanced breast cancer metastasis inhibition 期刊论文  OAI收割 BIOMATERIALS, 2020, 卷号: 257, 页码: 13 作者:  Wang, Kaiyuan;  Ye, Hao;  Zhang, Xuanbo;  Wang, Xia;  Yang, Bin   |  收藏  |  浏览/下载：44/0  |  提交时间：2020/12/24 Exosome membrane  Cucurbitacin B  Paclitaxel  Breast cancer metastasis  Programmable bioactivation   A phase II randomized trial of sodium oligomannate in Alzheimer’s dementia 期刊论文  OAI收割 Alzheimer's Research & Therapy, 2020, 卷号: 12, 期号: 1 作者:  Wang,Tao;  Kuang,Weihong;  Chen,Wei;  Xu,Wenwei;  Zhang,Liming   |  收藏  |  浏览/下载：74/0  |  提交时间：2020/12/24 Sodium oligomannate  Efficacy  Safety  Alzheimer’s disease  Clinical trial   A phase II randomized trial of sodium oligomannate in Alzheimer's dementia 期刊论文  OAI收割 ALZHEIMERS RESEARCH & THERAPY, 2020, 卷号: 12, 期号: 1, 页码: 10 作者:  Wang, Tao;  Kuang, Weihong;  Chen, Wei;  Xu, Wenwei;  Zhang, Liming   |  收藏  |  浏览/下载：73/0  |  提交时间：2020/12/21 Sodium oligomannate  Efficacy  Safety  Alzheimer's disease  Clinical trial   SAF-189s, a potent new-generation ROS1 inhibitor, is active against crizotinib-resistant ROS1 mutant-driven tumors 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 7 作者:  Xia, Zong-jun;  Ji, Yin-chun;  Sun, De-qiao;  Peng, Xia;  Gao, Ying-lei   |  收藏  |  浏览/下载：47/0  |  提交时间：2020/12/21 ROS1 kinase  ROS1 inhibitor  SAF-189s  lorlatinib  crizotinib resistance  G2032R mutant  NSCLC   Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels 期刊论文  OAI收割 JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 31, 页码: 10842-10856 作者:  Liu, Wen;  Yin, Ye;  Wang, Meijing;  Fan, Ting;  Zhu, Yuyu   |  收藏  |  浏览/下载：86/0  |  提交时间：2020/12/24 Src homology 2 domain containing tyrosine phosphatase-2 (SHP2)  hepatic steatosis  insulin resistance  caspase-1  interleukin 18 (IL-18)  fatty liver  metabolic disorder  inflammation  cytokine signaling  caspase 1 (CASP1)  tyrosine-protein phosphatase (tyrosine phosphatase)  macrophage   AMPK activator C24 inhibits hepatic lipogenesis and ameliorates dyslipidemia in HFHC diet-induced animal models 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8 作者:  Sun, Shui-mei;  Xie, Zhi-fu;  Zhang, Yang-ming;  Zhang, Xin-wen;  Zhou, Chen-dong   |  收藏  |  浏览/下载：27/0  |  提交时间：2020/12/24 adenosine 5 '-monophosphate-activated protein kinase  AMPK activator  C24  liver  triglycerides  cholesterol  VLDL  hypolipidemic drug  metabolic syndrome   Geng et al. reply 期刊论文  OAI收割 CELL RESEARCH, 2020, 页码: 1 作者:  Wang, Xinyi;  Sun, Guangqiang;  Feng, Teng;  Zhang, Jing;  Huang, Xun   |  收藏  |  浏览/下载：73/0  |  提交时间：2020/12/24 Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance 期刊论文  OAI收割 MOLECULAR CANCER, 2020, 卷号: 19, 期号: 1, 页码: 15 作者:  Zhang, Tao;  Qu, Rong;  Chan, Shingpan;  Lai, Mengzhen;  Tong, Linjiang   |  收藏  |  浏览/下载：79/0  |  提交时间：2020/07/01 Non-small cell lung cancer (NSCLC)  EGFR T790M  Small-molecule inhibitor  Drug resistance  Ack1   Sepiapterin reductase promotes hepatocellular carcinoma progression via FoxO3a/Bim signaling in a nonenzymatic manner 期刊论文  OAI收割 CELL DEATH & DISEASE, 2020, 卷号: 11, 期号: 4, 页码: 14 作者:  Wu, Yao;  Du, Hongzhi;  Zhan, Meixiao;  Wang, Hongxv;  Chen, Peng   |  收藏  |  浏览/下载：46/0  |  提交时间：2020/07/01