中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [9]
合肥物质科学研究院 [2]
武汉物理与数学研究所 [1]
自动化研究所 [1]
采集方式
OAI收割 [13]
内容类型
期刊论文 [13]
发表日期
2023 [1]
2022 [1]
2021 [1]
2020 [2]
2019 [1]
2018 [3]
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SYK-mediated epithelial cell state is associated with response to c-Met inhibitors in c-Met-overexpressing lung cancer
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 13
作者:
Zhou, Ji
;
Zhang, Xu-Chao
;
Xue, Shan
;
Dai, Mengdi
;
Wang, Yueliang
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Disease progression patterns and molecular resistance mechanisms to crizotinib of lung adenocarcinoma harboring ROS1 rearrangements
期刊论文
OAI收割
NPJ PRECISION ONCOLOGY, 2022, 卷号: 6
作者:
Zhang, Yongchang
;
Huang, Zhe
;
Zeng, Liang
;
Zhang, Xiangyu
;
Li, Yizhi
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2022/05/05
A Case of Resistance to Selective RET-TKI Therapy With Pleural-Genotyped MET Amplification and Response to Crizotinib
期刊论文
OAI收割
CLINICAL LUNG CANCER, 2021, 卷号: 22
作者:
Chen, Kaiyan
;
Zhang, Fanrong
;
Pan, Guoqiang
;
Sheng, Jiamin
;
Ye, Junyi
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2021/03/15
Crizotinib
MET
Non-small-cell lung cancer
RET
Resistance
SAF-189s, a potent new-generation ROS1 inhibitor, is active against crizotinib-resistant ROS1 mutant-driven tumors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 7
作者:
Xia, Zong-jun
;
Ji, Yin-chun
;
Sun, De-qiao
;
Peng, Xia
;
Gao, Ying-lei
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/12/21
ROS1 kinase
ROS1 inhibitor
SAF-189s
lorlatinib
crizotinib resistance
G2032R mutant
NSCLC
CT-Based Radiomic Signature as a Prognostic Factor in Stage IV ALK-Positive Non-small-cell Lung Cancer Treated With TKI Crizotinib: A Proof-of-Concept Study
期刊论文
OAI收割
FRONTIERS IN ONCOLOGY, 2020, 卷号: 10, 页码: 9
作者:
Li, Hailin
;
Zhang, Rui
;
Wang, Siwen
;
Fang, Mengjie
;
Zhu, Yongbei
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2020/04/07
computed tomography
radiomics
non-small-cell lung cancer
tyrosine kinase inhibitor resistance
anaplastic lymphoma kinase
SHR-A1403, a novel c-mesenchymal-epithelial transition factor (c-Met) antibody-drug conjugate, overcomes AZD9291 resistance in non-small cell lung cancer cells overexpressing c-Met
期刊论文
OAI收割
CANCER SCIENCE, 2019, 页码: 11
作者:
Tong, Mengya
;
Gao, Mingzhao
;
Xu, Yongping
;
Fu, Li
;
Li, Yun
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/07/01
AZD9291
c-Met ADC
c-Met overexpression
resistance
SHR-A1403
Design, synthesis and pharmacological evaluation of ALK and Hsp90 dual inhibitors bearing resorcinol and 2,4-diaminopyrimidine motifs
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 76-86
作者:
Geng, Kaijun
;
Liu, Hongchun
;
Song, Zilan
;
Zhang, Chi
;
Zhang, Minmin
  |  
收藏
  |  
浏览/下载:146/0
  |  
提交时间:2019/01/08
Heat shock protein 90 (Hsp90)
Tyrosine kinase ALK
Dual inhibitor
Drug resistance
Antiproliferative activity
Discovery of 2,4-diarylaminopyrimidines bearing a resorcinol motif as novel ALK inhibitors to overcome the G1202R resistant mutation
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 144, 页码: 386-397
作者:
Geng, Kaijun
;
Xia, Zongjun
;
Ji, Yinchun
;
Zhang, Ruisi (Ruthy)
;
Sun, Deqiao
  |  
收藏
  |  
浏览/下载:125/0
  |  
提交时间:2019/01/08
ALK
G1202R mutant
Drug resistance
2,4-Diarylaminopyrimidine
Resorcinol
Pharmacologic characterization of CT-711, a novel dual inhibitor of ALK and c-Met
期刊论文
OAI收割
AMERICAN JOURNAL OF CANCER RESEARCH, 2018, 卷号: 8, 期号: 8, 页码: 1541-1550
作者:
Wang, Lei
;
Gao, Mingzhao
;
Tong, Mengya
;
Xie, Chengying
;
He, Ye
  |  
收藏
  |  
浏览/下载:121/0
  |  
提交时间:2019/01/08
CT-711
ALK
c-Met
crizotinib
antitumor activity
pharmacokinetics
Serum Metabolic Profile Alteration Reveals Response to Platinum-Based Combination Chemotherapy for Lung Cancer: Sensitive Patients Distinguished from Insensitive ones
期刊论文
OAI收割
SCIENTIFIC REPORTS, 2017, 卷号: 7
作者:
Xu, Shan
;
Zhou, Yanping
;
Geng, Hui
;
Song, Dandan
;
Tang, Jing
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2018/11/05