中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [101]
采集方式
OAI收割 [101]
内容类型
期刊论文 [101]
发表日期
2021 [101]
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发表日期:2021
内容类型:期刊论文
专题:上海药物研究所
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Requirments for primary human hepatocyte
期刊论文
OAI收割
CELL PROLIFERATION, 2021, 页码: 6
作者:
Peng, Zhaoliang
;
Wu, Jiaying
;
Hu, Shijun
;
Ma, Aijin
;
Wang, Lei
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/06/15
primary human hepatocyte
quality control
standard
A camptothecin-based, albumin-binding prodrug enhances efficacy and safety in vivo
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 226, 页码: 11
作者:
Cheng, Zhiyang
;
Huang, Ying
;
Shen, Qianqian
;
Zhao, Yangrong
;
Wang, Lei
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/11/04
Cancer
beta-glucuronidase
Bioconjugation
Albumin
Camptothecin
Conformational polymorphs of isotretinoin and their impact on physicochemical and biological properties
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2021, 卷号: 610, 页码: 10
作者:
Cheng, Yinxiang
;
Rong, Xiaoyi
;
Xia, Mengyuan
;
Zhang, Zaiyong
;
Wang, Jian-Rong
  |  
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2022/01/04
Polymorph
Isotretinoin
Stability
Solubility
Bioavailability
Design, synthesis and biological evaluation of a novel spiro oxazolidinedione as potent p300/CBP HAT inhibitor for the treatment of ovarian cancer
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 52, 页码: 12
作者:
Ding, Hong
;
Pei, Yuan
;
Li, Yuanqing
;
Xu, Wen
;
Mei, Lianghe
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/06/15
Epigenetics
Histone acetyltransferase
P300/CBP
Ovarian cancer
Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Li, Teng-teng
;
Peng, Cheng
;
Wang, Ji-qiu
;
Xu, Zhi-jian
;
Su, Ming-bo
  |  
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2022/01/18
DPP4
distal mutation
enzymatic activity
molecular dynamics simulation
structure-function mechanism
Eutectic molten salt assisted synthesis of highly defective and flexible ruthenium oxide for efficient overall water splitting
期刊论文
OAI收割
CHEMICAL ENGINEERING JOURNAL, 2021, 卷号: 425, 页码: 10
作者:
Peng, Chunlei
;
Zhao, Wanpeng
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2022/01/04
Molten salt
Ruthenium oxide
Overall water splitting
Low-crystallinity
Nanosheets
Structure-Based Design of Dual-Acting Compounds Targeting Adenosine A(2A) Receptor and Histone Deacetylase as Novel Tumor Immunotherapeutic Agents
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 22, 页码: 16573-16597
作者:
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/06/15
NIR-II imaging of hepatocellular carcinoma based on a humanized anti-GPC3 antibody
期刊论文
OAI收割
RSC MEDICINAL CHEMISTRY, 2021, 页码: 8
作者:
Shi, Hui
;
Huttad, Lakshmi Vageesh
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/01/04
Rapamycin recruits SIRT2 for FKBP12 deacetylation during mTOR activity modulation in innate immunity
期刊论文
OAI收割
ISCIENCE, 2021, 卷号: 24, 期号: 11, 页码: 22
作者:
Hu, Lin
;
Chen, Fuxian
;
Wu, Chao
;
Wang, Jun
;
Chen, Si-si
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2022/01/18
Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site
期刊论文
OAI收割
ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 11, 页码: 2444-2452
作者:
Wang, Jiang
;
Yang, Dehua
;
Cheng, Xi
;
Yang, Linlin
;
Wang, Zhaohui
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/01/04