中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [11]
采集方式
OAI收割 [11]
内容类型
期刊论文 [11]
发表日期
2021 [11]
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发表日期:2021
内容类型:期刊论文
专题:上海药物研究所
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Design, Synthesis, and Pharmacological Evaluation of Biaryl-Containing PD-1/PD-L1 Interaction Inhibitors Bearing a Unique Difluoromethyleneoxy Linkage
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 22, 页码: 16687-16702
作者:
Song, Zilan
;
Liu, Bo
;
Peng, Xia
;
Gu, Wangting
;
Sun, Yiming
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2022/06/15
Amygdalar k-opioid receptor-dependent upregulating glutamate transporter 1 mediates depressive-like behaviors of opioid abstinence
期刊论文
OAI收割
CELL REPORTS, 2021, 卷号: 37, 期号: 5, 页码: 21
作者:
Zan, Gui-Ying
;
Wang, Yu-Jun
;
Li, Xue-Ping
;
Fang, Jun-Fan
;
Yao, Song-Yu
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2021/12/16
Exploring biological basis of Syndrome differentiation in coronary heart disease patients with two distinct Syndromes by integrated multi-omics and network pharmacology strategy
期刊论文
OAI收割
Chinese Medicine, 2021, 卷号: 16, 期号: 1
作者:
Wu,Gaosong
;
Zhao,Jing
;
Zhao,Jing
;
Song,Nixue
;
Zheng,Ningning
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/12/01
Coronary heart disease
Syndrome differentiation
Traditional Chinese Medicine
Proteomics
Metabolomics
Network pharmacology
Novel selective kappa agonists SLL-039 and SLL-1206 produce potent antinociception with fewer sedation and aversion
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Wei, Yuan-yuan
;
Ma, Yan
;
Yao, Song-yu
;
Kong, Ling-hui
;
Liu, Xiao
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2021/11/04
kappa-opioid receptor agonist
4,5-expoxymorphinan
antinociception
conditioned place aversion
sedation
U50,488H
morphine
Nor-BNI
beta-FNA
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhou, Yu-bo
;
Zhang, Yang-ming
;
Huang, Hong-hui
;
Shen, Li-jing
;
Han, Xiao-feng
  |  
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2021/11/04
multiple myeloma
HDAC inhibitor
bisthianostat
pharmacodynamics
pharmacokinetics
phase 1a clinical trial
antitumor drug
Acidity-Activatable Dynamic Nanoparticles Boosting Ferroptotic Cell Death for Immunotherapy of Cancer
期刊论文
OAI收割
ADVANCED MATERIALS, 2021, 卷号: 33, 期号: 31, 页码: 2101155
作者:
Song, Rundi
;
Li, Tianliang
;
Ye, Jiayi
;
Sun, Fang
;
Hou, Bo
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/03/21
cancer immunotherapy
ferroptosis
immune resistance
immunogenic cell death
T lymphocytes
Development of Potent NEDD8-Activating Enzyme Inhibitors Bearing a Pyrimidotriazole Scaffold
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 9, 页码: 6161-6178
作者:
Xiong, Chaodong
;
Zhou, Lina
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/08/17
Natural product 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Li, Wen
;
Liao, Li-ping
;
Song, Ning
;
Liu, Yan-jun
;
Ding, Yi-luan
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/06/11
glyceraldehyde 3-phosphate dehydrogenase
1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose
hydrogen deuterium exchange mass spectrometry
reversible inhibitor
glycolysis
Natural product 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Li, Wen
;
Liao, Li-ping
;
Song, Ning
;
Liu, Yan-jun
;
Ding, Yi-luan
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/06/11
glyceraldehyde 3-phosphate dehydrogenase
1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose
hydrogen deuterium exchange mass spectrometry
reversible inhibitor
glycolysis
Ube2b-dependent degradation of DNMT3a relieves a transcriptional brake on opiate-induced synaptic and behavioral plasticity
期刊论文
OAI收割
MOLECULAR PSYCHIATRY, 2021, 卷号: 26, 期号: 4, 页码: 1162-1177
作者:
Chen, Zhong-Guo
;
Wang, Yu-Jun
;
Chen, Ruo-Song
;
Geng, Fan
;
Gan, Chen-Ling
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/05/24