机构

• 上海药物研究所 [148]

采集方式

• OAI收割 [148]

内容类型

• 期刊论文 [148]

发表日期

• 2024 [2]
• 2023 [19]
• 2022 [13]
• 2021 [18]
• 2020 [21]
• 2019 [13]
• 更多

学科主题

• Chemistry [1]
• Pharmacolo... [1]

筛选

浏览/检索结果: 共148条，第1-10条 帮助 限定条件 内容类型：期刊论文    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 Discovery of potent PROTAC degraders of Pin1 for the treatment of acute myeloid leukemia 期刊论文  OAI收割 CHEMICAL SCIENCE, 2024, 卷号: 15, 期号: 13, 页码: 5027-5035 作者:  Shi, Yunkai;  Liu, Minmin;  Li, Mengna;  Mao, Yiwen;  Ma, Jingkun   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/05/07 Sesquiterpenoids and Cytochalasins with Immunosuppressive Activity from Sonchus wightianus 期刊论文  OAI收割 CHEMISTRY & BIODIVERSITY, 2024, 页码: 9 作者:  Xie, Zhi-Xiang;  Cui, Yong-Sheng;  Liu, Xi-Hong;  Yao, Jia-Ying;  He, Shi-Jun   |  收藏  |  浏览/下载：3/0  |  提交时间：2024/05/07 Sonchus wightianus  guaiane-type sesquiterpenoid  cytochalasin  electronic circular dichroism  immunosuppressive activity   C-terminal modification and functionalization of proteins via a self-cleavage tag triggered by a small molecule 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 13 作者:  Zeng, Yue;  Shi, Wei;  Liu, Zhi;  Xu, Hao;  Liu, Liya   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/02/19 ABPP-CoDEL: Activity-Based Proteome Profiling-Guided Discovery of Tyrosine-Targeting Covalent Inhibitors from DNA-Encoded Libraries 期刊论文  OAI收割 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2023, 卷号: 145, 期号: 46, 页码: 25283-25292 作者:  Jiang, Lulu;  Liu, Sixiu;  Jia, Xinglong;  Gong, Qinting;  Wen, Xin   |  收藏  |  浏览/下载：30/0  |  提交时间：2024/01/16 Design, synthesis, and STING-agonistic activity of benzo[b]thiophene-2-carboxamide derivatives 期刊论文  OAI收割 MOLECULAR DIVERSITY, 2023, 页码: 10 作者:  Zhou, Rongyao;  Wang, Xiyuan;  Zhang, Deqiang;  Zhan, Zhengsheng;  Duan, Wenhu   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/08 STING  CDN  Benzo[b]thiophene-2-carboxamide  Cellular activity   Addition of a-synuclein aggregates to the intestinal environment recapitulates Parkinsonian symptoms in model systems 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 16 作者:  Yang, Ze-xian;  Zhang, Yu;  Wang, Qing;  Zhang, Lei;  Liu, Yi-fei   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/12/08 Parkinson's disease  gut-brain axis  a-Synuclein  inflammation  microbiota  intestinal mouse coloclysis model   Otilonium Bromide acts as a selective USP28 inhibitor and exhibits cytotoxic activity against multiple human cancer cell lines 期刊论文  OAI收割 BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 215, 页码: 14 作者:  Xu, Zhuo;  Wang, Hui;  Meng, Qian;  Ding, Yiluan;  Zhu, Mengying   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 Otilonium Bromide  Deubiquitinase  USP28  Selective inhibitor   Human Aha1's N-terminal extension confers it holdase activity in vitro 期刊论文  OAI收割 PROTEIN SCIENCE, 2023, 卷号: 32, 期号: 9, 页码: 15 作者:  Tang, Junying;  Hu, Huifang;  Zhou, Chen;  Zhang, Naixia   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17 Aha1  holdase activity  intrinsically disordered region  NMR  N-terminal extension   Pharmacological targeting of Axin2 suppresses cell growth and metastasis in colorectal cancer 期刊论文  OAI收割 BRITISH JOURNAL OF PHARMACOLOGY, 2023, 页码: 21 作者:  Cheng, Li-Zhi;  Huang, Dan-Ling;  Tang, Zhang-Rui;  Zhang, Jia-Hao;  Xiong, Ting   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/10/17 colorectal cancer progression  GSK3 beta-Axin2 interaction  small-molecule inhibitor  Snail  beta-Trcp2   An unusual four-step cascade reaction for accessing furo[3,4-c]pyridine-1,4-diones via rhodium catalysis 期刊论文  OAI收割 ORGANIC CHEMISTRY FRONTIERS, 2023, 页码: 7 作者:  Li, Yidi;  Xu, Huiying;  Zhou, Zhi;  Huang, Lin;  Tang, Zhenhao   |  收藏  |  浏览/下载：5/0  |  提交时间：2023/10/17