中国科学院机构知识库网格
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Molecular and physiological responses in the ammonia transport pathways in clam
Cyclina
sinensis
exposed to chronic ammonia nitrogen
期刊论文
OAI收割
AQUACULTURE REPORTS, 2024, 卷号: 35, 页码: 9
作者:
Ni, Qian
;
Liang, Xiafei
;
Yang, Shengyi
;
Ge, Hongxing
;
Dong, Zhiguo
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/04/07
CsRhbg
GSase
GDH activity
Cyclina sinensis
Chronic ammonia nitrogen exposure
Novel imidazo[1,2,4] triazole derivatives: Synthesis, fluorescence, bioactivity for SHP1
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 15
作者:
Yan, Xue
;
Zhang, Chun
;
Gao, Li-Xin
;
Liu, Min -Min
;
Yang, Yu-Ting
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
Imidazo[124] triazole derivatives
Fluorescence property
SHP1
Bioactivity
Cellular imaging
Discovery, Optimization, and Evaluation of Novel Pyridin-2(1
H
)-one Analogues as Potent TRK Inhibitors for Cancer Treatment
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1168-1183
作者:
Xu, Zichao
;
Peng, Xia
;
Zhang, Renjie
;
Ji, Yinchun
;
You, Mengke
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/02/27
Structure-based design of potent FABP4 inhibitors with high selectivity against FABP3
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 10
作者:
Chen, Guofeng
;
Xie, Hang
;
Liu, Jiayuan
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
Methyl substitution
Selectivity
FABP4 inhibitor
Anti-inflammation
Metabolic stability
SIBP-03, a novel anti-HER3 antibody, exerts antitumor effects and synergizes with EGFR- and HER2-targeted drugs
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 10
作者:
Li, Wen-jing
;
Xie, Cheng-ying
;
Zhu, Xi
;
Tang, Jiao
;
Wang, Lei
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/02/19
SIBP-03
HER3
HER3-targeted therapy
neuregulin 1
EGFR
HER2
Discovery of hematopoietic progenitor kinase 1 inhibitors using machine learning-based screening and free energy perturbation
期刊论文
OAI收割
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2024, 页码: 13
作者:
Feng, Dazhi
;
Liu, Bo
;
Chen, Zhiwei
;
Xu, Jinyi
;
Geng, Meiyu
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/02/27
HPK1 inhibitor
machine learning
virtual screening
free energy perturbation
structural modification
Calcium oxide nanoparticles mitigate lead stress in
Abelmoschus
esculentus
though improving the key antioxidative enzymes, nutritional content and modulation of stress markers
期刊论文
OAI收割
PLANT PHYSIOLOGY AND BIOCHEMISTRY, 2024, 卷号: 206, 页码: 10
作者:
Raza, Hafiz Zulqurnain
;
Shah, Anis Ali
;
Noreen, Zahra
;
Usman, Sheeraz
;
Zafar, Sadia
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/22
Antioxidant
Calcium
Growth
Nanoparticle
Okra
Mixed micelles loaded with hesperidin protect against acetaminophen induced acute liver injury by inhibiting the mtDNA-cGAS-STING pathway
期刊论文
OAI收割
COLLOIDS AND SURFACES B-BIOINTERFACES, 2024, 卷号: 233, 页码: 12
作者:
Dong, Kehong
;
Sun, Yuxuan
;
Gao, Xintao
;
Wang, Jing
;
Wu, Xiaochen
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/04/07
Acetaminophen
Liver injury
Hesperidin
MtDNA
CGAS-STING
CA1中央区NMDA受体G1uN3A亚基参与应激致抑郁和D-serine杭抑郁的细胞和环路机制
学位论文
OAI收割
中国科学院心理研究所: 中国科学院大学, 2023
作者:
张伟
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/05
抑郁相关行为
NMDA受体G1uN3A亚基
海马CA1
锥体神经元
D一丝氨酸
Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933
作者:
Fang, Feifei
;
Dai, Yang
;
Wang, Hao
;
Ji, Yinchun
;
Liang, Xuewu
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/26
derivatives
Antitumor drug development
Potential AXL inhibitor
Antitumor activity
Structure-based drug design
Fused-pyrazolone carboxamide