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  • 上海药物研究所 [10]
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浏览/检索结果: 共10条，第1-10条 帮助

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Discovery of an M-Substituted N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active kappa-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12414-12433
作者:  He, Qian;  Wei, Yuanyuan;  Liu, Xiao;  Ye, Rongrong;  Kong, Linghui
  |  收藏  |  浏览/下载：83/0  |  提交时间：2021/11/04
Exploration of the SAR Connection between Morphinan- and Arylacetamide-Based kappa Opioid Receptor (kappa OR) Agonists Using the Strategy of Bridging 期刊论文  OAI收割
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 6, 页码: 1018-1030
作者:  Liu, Xiao;  Jiang, Shuang;  Kong, Linghui;  Ye, Rongrong;  Xiao, Li
  |  收藏  |  浏览/下载：83/0  |  提交时间：2021/05/24
Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:  Xiao, Li;  Wang, Yujun;  Zhang, Mumei;  Wu, Weiwei;  Kong, Linghui
  |  收藏  |  浏览/下载：81/0  |  提交时间：2020/07/01
7 beta-Methyl substituent is a structural locus associated with activity cliff for nepenthone analogues 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 14, 页码: 4254-4263
作者:  Sun, Hui-jiao;  Wang, Yu-hua;  Yuan, Cong-min;  Kong, Ling-hui;  Xu, Xue-jun
  |  收藏  |  浏览/下载：79/0  |  提交时间：2019/01/08
Switching off IMMP2L signaling drives senescence via simultaneous metabolic alteration and blockage of cell death 期刊论文  OAI收割
CELL RESEARCH, 2018, 卷号: 28, 期号: 6, 页码: 625-643
作者:  Yuan, Lifeng;  Zhai, Linhui;  Qian, Lili;  Huang, De;  Ding, Yi
  |  收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08
Novel CHOP activator LGH00168 induces necroptosis in A549 human lung cancer cells via ROS-mediated ER stress and NF-kappa B inhibition 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1381-1390
作者:  Ma, Yi-ming;  Peng, Yan-min;  Zhu, Qiong-hua
  |  收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08
Fluorogenic Resveratrol-Confined Graphene Oxide For Economic and Rapid Detection Of Alzheimer's Disease 期刊论文  OAI收割
ACS APPLIED MATERIALS & INTERFACES, 2014, 卷号: 6, 期号: 8, 页码: 5379-5382
作者:  He, Xiao-Peng;  Deng, Qiong;  Cai, Liang;  Wang, Chang-Zheng;  Zang, Yi
  |  收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08
Functional Characterization of Three Mouse Formyl Peptide Receptors 期刊论文  OAI收割
MOLECULAR PHARMACOLOGY, 2013, 卷号: 83, 期号: 2, 页码: 389-398
作者:  He, Hui-Qiong;  Liao, Dan;  Wang, Zhen-Guo;  Wang, Zhong-Li;  Zhou, Hu-Chen
  |  收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08
Identification of diverse 1,2,3-triazole-connected benzyl glycoside-serine/threonine conjugates as potent corrosion inhibitors for mild steel in HCl 期刊论文  OAI收割
CORROSION SCIENCE, 2012, 卷号: 64, 页码: 64-73
作者:  Deng, Qiong;  Ding, Na-Na;  Wei, Xiao-Li;  Cai, Liang;  He, Xiao-Peng
  |  收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08
Facile fabrication of promising protein tyrosine phosphatase (PTP) inhibitor entities based on 'clicked' serine/threonine-monosaccharide hybrids 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2011, 卷号: 19, 期号: 13, 页码: 3892-3900
作者:  He, Xiao-Peng;  Deng, Qiong;  Gao, Li-Xin;  Li, Cui;  Zhang, Wei
  |  收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08