中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [24]
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Activating CD8
+
T Cells by Pt(IV) Prodrug-Based Nanomedicine and aPD-L1 Antibody for Enhanced Cancer Immunotherapy
期刊论文
OAI收割
ADVANCED MATERIALS, 2024, 页码: 15
作者:
Wang, Bin
;
Zhou, Jingyu
;
Li, Ruitong
;
Tang, Dongsheng
;
Cao, Zheng
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/04/09
chemotherapy
immunotherapy
immunogenic cell death
tumor immune microenvironment
Vitamin B2-Based Ferroptosis Promoter for Sono-Enhanced Nanocatalytic Therapy of Triple-Negative Breast Cancer
期刊论文
OAI收割
ADVANCED FUNCTIONAL MATERIALS, 2023, 页码: 12
作者:
Zhou, Mengjiao
;
Yuan, Minjian
;
Jin, Yilan
;
Zhou, Qianqian
;
Yu, Yuting
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
ferroptosis
nanocatalytic therapy
oxidative stress
redox homeostasis
Bispecific antibody targeting both B7-H3 and PD-L1 exhibits superior antitumor activities
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 9
作者:
Li, Hua-ying
;
Chen, Yi-li
;
Deng, Xiang-nan
;
Li, Huan-huan
;
Tan, Jie
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/10/17
cancer immunotherapy
B7-H3
PD-L1
bispecific antibodies
VHH
antibody-dependent cell-mediated cytotoxicity (ADCC)
PD-L1/TLR7 dual-targeting nanobody-drug conjugate mediates potent tumor regression via elevating tumor immunogenicity in a host-expressed PD-L1 bias-dependent way
期刊论文
OAI收割
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 卷号: 10, 期号: 10, 页码: 15
作者:
Yu, Xiaolu
;
Long, Yiru
;
Chen, Binfan
;
Tong, Yongliang
;
Shan, Mengwen
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/12/13
PD-L1
TLR7
nanobody-drug-conjugate
cancer immunotherapy
A Peritumorally Injected Immunomodulating Adjuvant Elicits Robust and Safe Metalloimmunotherapy against Solid Tumors
期刊论文
OAI收割
ADVANCED MATERIALS, 2022, 页码: 12
作者:
Zhang, Lingxiao
;
Zhao, Jing
;
Hu, Xi
;
Wang, Chenhan
;
Jia, Yingbo
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/02/24
immunogenic cell death
layered double hydroxide
nutritional metal ions
tumor microenvironment
vaccine adjuvants
Advances on Delivery of Cytotoxic Enzymes as Anticancer Agents
期刊论文
OAI收割
MOLECULES, 2022, 卷号: 27, 期号: 12, 页码: 35
作者:
Asrorov, Akmal M.
;
Muhitdinov, Bahtiyor
;
Tu, Bin
;
Mirzaakhmedov, Sharafitdin
;
Wang, Huiyuan
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/08/16
enzyme drugs
cancer therapy
trichosanthin
gelonin
peroxidase
glucose oxidase
asparaginase
exotoxin
diphtheria toxin
Impact of cumulative cisplatin dose in childhood nasopharyngeal carcinoma based on neoadjuvant chemotherapy response in the intensity-modulated radiotherapy era: a real-world study
期刊论文
OAI收割
CANCER CELL INTERNATIONAL, 2021, 卷号: 21
作者:
Jin, Ya-Nan
;
Qiang, Meng-Yun
;
Liu, Meng-Meng
;
Cheng, Zhi-Bin
;
Zhang, Wang-Jian
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/01/10
Nasopharyngeal carcinoma
Cumulative cisplatin dose
Children and adolescents
Tumor response
Neoadjuvant chemotherapy
A validated HPLC-MS/MS method for determination of simmitecan and its metabolite chimmitecan in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor
期刊论文
OAI收割
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 8
作者:
Zhou, Jun
;
Zhan, Yan
;
Zhong, Dafang
;
Chen, Xiaoyan
;
Zhang, Yifan
  |  
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2021/11/04
chimmitecan
mass spectrometry
pharmacokinetics
simmitecan
solid tumors
A phase I study of the safety and activity of K-001 in patients with advanced pancreatic ductal adenocarcinoma
期刊论文
OAI收割
BMC Cancer, 2021, 卷号: 21, 期号: 1
作者:
Cui,Jiujie
;
Yang,Haiyan
;
Liu,Jue
;
Chen,Donghui
;
Hu,Jiong
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/06/15
Pancreatic ductal adenocarcinoma
Phase I study
Safety
K-001
Clinical trial
Engineering the Deformability of Albumin-Stabilized Emulsions for Lymph-Node Vaccine Delivery
期刊论文
OAI收割
ADVANCED MATERIALS, 2021, 页码: 10
作者:
Song, Tiantian
;
Xia, Yufei
;
Du, Yiqun
;
Chen, Michael W.
;
Qing, Hong
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/08/31
albumin‐
stabilized emulsions
deformability
lymph node targeting
vaccines
vaccine delivery systems