中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Discovery and Optimization of Novel Nonbile Acid FXR Agonists as Preclinical Candidates for the Treatment of Inflammatory Bowel Disease
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 7, 页码: 5642-5661
作者:
Li, Yuan
;
Xu, Tingting
;
Zhao, Yue
;
Zhang, Hui
;
Liu, Zesheng
  |  
收藏
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浏览/下载:3/0
  |  
提交时间:2024/05/07
Effects of glyphosate exposure on gut-liver axis: Metabolomic and mechanistic analysis in grass carp (Ctenopharyngodon idellus)
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 902, 页码: 12
作者:
Yan, Biao
;
Sun, Yumiao
;
Fu, Kaiyu
;
Zhang, Yindan
;
Lei, Lei
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/26
Glyphosate
Metabolomics
Grass carp
Gut-Liver axis
Saikosaponin D improves nonalcoholic fatty liver disease via gut microbiota-bile acid metabolism pathway
期刊论文
OAI收割
Food Science and Human Wellness, 2023
作者:
Li, Lan
;
Yang, Shengye
;
Liang, Xinyu
;
Liu, Yameng
;
Xu, Hualing
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/03/26
Gut Microbiota
Non-alcoholic Fatty Liver Disease
Ssd
Bile Acids
Farnesoid x Receptor
Hyodeoxycholic acid alleviates non-alcoholic fatty liver disease through modulating the gut-liver axis
期刊论文
OAI收割
CELL METABOLISM, 2023, 卷号: 35, 期号: 10, 页码: 1752-+
作者:
Kuang, Junliang
;
Wang, Jieyi
;
Li, Yitao
;
Li, Mengci
;
Zhao, Mingliang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
Saikosaponins regulate bile acid excretion in mice liver and ileum by activating farnesoid X receptor and bile acid transporter
期刊论文
OAI收割
PHYTOTHERAPY RESEARCH, 2023, 页码: 15
作者:
Wang, YuKun
;
Li, Jing
;
Wu, Li
;
Qin, XueMei
;
Xie, Cen
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/10/17
bile acids
enterohepatic circulation
FXR-related genes
saikosaponins
Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 1829
作者:
Zhao,Qi
;
Dai,Man-Yun
;
Huang,Ruo-Yue
;
Duan,Jing-Yi
;
Zhang,Ting
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/05/09
FATTY LIVER-DISEASE
INDUCED CHOLESTASIS
STELLATE CELLS
PROBIOTICS
PROTECTS
INFLAMMATION
APOPTOSIS
OBESITY
AXIS
ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 22, 页码: e2220148120
作者:
Zhou,Gui-Feng
;
Tang,Jing
;
Ma,Yuan-Lin
;
Fu,Xian
;
Liu,Jun-Yan
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/09
conophylline
ARL6IP1
5'UTR
FXR1
BACE1 translation
AMYLOID PRECURSOR PROTEIN
A-BETA
TRANSGENIC MICE
MOUSE MODEL
NEURODEGENERATION
EXPRESSION
REDUCTION
MEMBRANE
MEMORY
ER
Hepatic thyroid hormone signalling modulates glucose homeostasis through the regulation of GLP-1 production via bile acid-mediated FXR antagonism
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 16
作者:
Yan, Ying
;
Niu, Zhoumin
;
Sun, Chao
;
Li, Peng
;
Shen, Siyi
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/12/13
Glycine-beta-muricholic acid antagonizes the intestinal farnesoid X receptor-ceramide axis and ameliorates NASH in mice
期刊论文
OAI收割
HEPATOLOGY COMMUNICATIONS, 2022, 页码: 16
作者:
Jiang, Jie
;
Ma, Yuandi
;
Liu, Yameng
;
Lu, Dasheng
;
Gao, Xiaoxia
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/11/11
Discovery of Betulinic Acid Derivatives as Potent Intestinal Farnesoid X Receptor Antagonists to Ameliorate Nonalcoholic Steatohepatitis
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 21
作者:
Zhang, Chenlu
;
Liu, Yameng
;
Wang, Ying
;
Ge, Xie
;
Jiao, Tingying
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/11/11