中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共92条,第1-10条 帮助

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Discovery and Optimization of Novel Nonbile Acid FXR Agonists as Preclinical Candidates for the Treatment of Inflammatory Bowel Disease 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 7, 页码: 5642-5661
作者:  
Li, Yuan;  Xu, Tingting;  Zhao, Yue;  Zhang, Hui;  Liu, Zesheng
  |  收藏  |  浏览/下载:3/0  |  提交时间:2024/05/07
Effects of glyphosate exposure on gut-liver axis: Metabolomic and mechanistic analysis in grass carp (Ctenopharyngodon idellus) 期刊论文  OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 902, 页码: 12
作者:  
Yan, Biao;  Sun, Yumiao;  Fu, Kaiyu;  Zhang, Yindan;  Lei, Lei
  |  收藏  |  浏览/下载:10/0  |  提交时间:2024/01/26
Saikosaponin D improves nonalcoholic fatty liver disease via gut microbiota-bile acid metabolism pathway 期刊论文  OAI收割
Food Science and Human Wellness, 2023
作者:  
Li, Lan;  Yang, Shengye;  Liang, Xinyu;  Liu, Yameng;  Xu, Hualing
  |  收藏  |  浏览/下载:20/0  |  提交时间:2024/03/26
Hyodeoxycholic acid alleviates non-alcoholic fatty liver disease through modulating the gut-liver axis 期刊论文  OAI收割
CELL METABOLISM, 2023, 卷号: 35, 期号: 10, 页码: 1752-+
作者:  
Kuang, Junliang;  Wang, Jieyi;  Li, Yitao;  Li, Mengci;  Zhao, Mingliang
  |  收藏  |  浏览/下载:8/0  |  提交时间:2023/12/08
Saikosaponins regulate bile acid excretion in mice liver and ileum by activating farnesoid X receptor and bile acid transporter 期刊论文  OAI收割
PHYTOTHERAPY RESEARCH, 2023, 页码: 15
作者:  
Wang, YuKun;  Li, Jing;  Wu, Li;  Qin, XueMei;  Xie, Cen
  |  收藏  |  浏览/下载:26/0  |  提交时间:2023/10/17
Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice 期刊论文  OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 1829
作者:  
Zhao,Qi;  Dai,Man-Yun;  Huang,Ruo-Yue;  Duan,Jing-Yi;  Zhang,Ting
  |  收藏  |  浏览/下载:3/0  |  提交时间:2024/05/09
ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation 期刊论文  OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 22, 页码: e2220148120
作者:  
Zhou,Gui-Feng;  Tang,Jing;  Ma,Yuan-Lin;  Fu,Xian;  Liu,Jun-Yan
  |  收藏  |  浏览/下载:1/0  |  提交时间:2024/05/09
Hepatic thyroid hormone signalling modulates glucose homeostasis through the regulation of GLP-1 production via bile acid-mediated FXR antagonism 期刊论文  OAI收割
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 16
作者:  
Yan, Ying;  Niu, Zhoumin;  Sun, Chao;  Li, Peng;  Shen, Siyi
  |  收藏  |  浏览/下载:30/0  |  提交时间:2022/12/13
Glycine-beta-muricholic acid antagonizes the intestinal farnesoid X receptor-ceramide axis and ameliorates NASH in mice 期刊论文  OAI收割
HEPATOLOGY COMMUNICATIONS, 2022, 页码: 16
作者:  
Jiang, Jie;  Ma, Yuandi;  Liu, Yameng;  Lu, Dasheng;  Gao, Xiaoxia
  |  收藏  |  浏览/下载:29/0  |  提交时间:2022/11/11
Discovery of Betulinic Acid Derivatives as Potent Intestinal Farnesoid X Receptor Antagonists to Ameliorate Nonalcoholic Steatohepatitis 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 21
作者:  
Zhang, Chenlu;  Liu, Yameng;  Wang, Ying;  Ge, Xie;  Jiao, Tingying
  |  收藏  |  浏览/下载:35/0  |  提交时间:2022/11/11