中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
昆明植物研究所 [1]
合肥物质科学研究院 [1]
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OAI收割 [9]
内容类型
期刊论文 [9]
发表日期
2023 [1]
2022 [3]
2021 [2]
2019 [1]
2018 [1]
2013 [1]
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Saikosaponins regulate bile acid excretion in mice liver and ileum by activating farnesoid X receptor and bile acid transporter
期刊论文
OAI收割
PHYTOTHERAPY RESEARCH, 2023, 页码: 15
作者:
Wang, YuKun
;
Li, Jing
;
Wu, Li
;
Qin, XueMei
;
Xie, Cen
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/10/17
bile acids
enterohepatic circulation
FXR-related genes
saikosaponins
Glycine-beta-muricholic acid antagonizes the intestinal farnesoid X receptor-ceramide axis and ameliorates NASH in mice
期刊论文
OAI收割
HEPATOLOGY COMMUNICATIONS, 2022, 页码: 16
作者:
Jiang, Jie
;
Ma, Yuandi
;
Liu, Yameng
;
Lu, Dasheng
;
Gao, Xiaoxia
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/11/11
Discovery of 9,11-Seco-Cholesterol Derivatives as Novel FXR Antagonists
期刊论文
OAI收割
ACS OMEGA, 2022, 卷号: 7, 期号: 20, 页码: 17401-17405
作者:
Zhou, Jia-Xu
;
Li, Cui-Na
;
Liu, Ya-Meng
;
Lin, Su-Qin
;
Wang, Ying
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/03/21
Farnesoid X receptor (FXR) agonists induce hepatocellular apoptosis and impair hepatic functions via FXR/SHP pathway
期刊论文
OAI收割
ARCHIVES OF TOXICOLOGY, 2022, 页码: 15
作者:
Zhang, Tianwei
;
Feng, Shanshan
;
Li, Jiahuan
;
Wu, Zhitao
;
Deng, Qiangqiang
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/06/15
FXR agonist
Hepatotoxicity
Farnesoid X receptor
Obeticholic acid
Px-102
Apoptosis
Discovery of novel ketoxime ether derivatives with potent FXR agonistic activity, oral effectiveness and high liver/blood ratio
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 43, 页码: 13
作者:
Tang, Xuehang
;
Ning, Mengmeng
;
Ye, Yangliang
;
Gu, Yipei
;
Yan, Hongyi
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/11/04
FXR agonist
Ketoxime ether
Target genes
Liver
blood ratio
Systemic activation
Construction of an RNA-Binding Protein-Related Prognostic Model for Pancreatic Adenocarcinoma Based on TCGA and GTEx Databases
期刊论文
OAI收割
FRONTIERS IN GENETICS, 2021, 卷号: 11
作者:
Wen, Xin
;
Shao, Zhiying
;
Chen, Shuyi
;
Wang, Wei
;
Wang, Yan
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/04/26
RNA-binding proteins (RBPs)
pancreatic adenocarcinoma (PAAD)
prognosis
TCGA
GTEx
Modulation of Lipid Metabolism by Celastrol
期刊论文
OAI收割
JOURNAL OF PROTEOME RESEARCH, 2019, 卷号: 18, 期号: 3, 页码: 1133-1144
作者:
Zhang, Ting
;
Zhao, Qi
;
Xiao, Xuerong
;
Yang, Rui
;
Hu, Dandan
  |  
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2019/04/15
celastrol
lipidomics
hyperlipidemia
LC-MS
HS218 as an FXR antagonist suppresses gluconeogenesis by inhibiting FXR binding to PGC-1 alpha promoter
期刊论文
OAI收割
METABOLISM-CLINICAL AND EXPERIMENTAL, 2018, 卷号: 85, 页码: 126-138
作者:
Xu, Xin
;
Shi, Xiaofan
;
Chen, Yidi
;
Zhou, Tingting
;
Wang, Jiaying
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/07/01
T2DM
Gluconeogenesis
FXR antagonist
PGC-1 alpha
Drug lead compound
Identification of 15d-PGJ(2) as an antagonist of farnesoid X receptor: Molecular modeling with biological evaluation
期刊论文
OAI收割
STEROIDS, 2013, 卷号: 78, 期号: 9, 页码: 813-822
作者:
Xu, Xing
;
Lul, Yin
;
Chen, Lili
;
Chen, Jing
;
Luo, Xiaomin
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
15-Deoxy-Delta(12,14)PGJ(2)
Farnesoid X receptor
Antagonist
Molecular dynamics simulation