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Chinese Academy of Sciences Institutional Repositories Grid
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Design and Synthesis Studies of α-Methylene-γ-butyrolactones Antagonists of GPR52 期刊论文  OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2023, 卷号: 43, 期号: 11, 页码: 3916-3929
作者:  
Shen, Donghang;  Li, Xin;  Guo, Shimeng;  Xie, Xin;  Nan, Fajun
  |  收藏  |  浏览/下载:13/0  |  提交时间:2024/02/27
GPR52 Antagonist Reduces Huntingtin Levels and Ameliorates Huntington's Disease-Related Phenotypes 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 2, 页码: 941-957
作者:  
Wang, Congcong;  Zhang, Yu-Fang;  Guo, Shimeng;  Zhao, Quan;  Zeng, Yanping
  |  收藏  |  浏览/下载:18/0  |  提交时间:2021/05/24
Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 卷号: 42, 期号: 10, 页码: 1556-1566
作者:  
Li, Xiao-jing;  Zhang, Yuan-yuan;  Fu, Yu-hua;  Zhang, Hao;  Li, He-xuan
  |  收藏  |  浏览/下载:15/0  |  提交时间:2024/03/21
应用鞣花酸治疗亨廷顿舞蹈病转基因小鼠的研究 学位论文  OAI收割
: 中国科学院大学, 2020
作者:  
孙勋
  |  收藏  |  浏览/下载:30/0  |  提交时间:2021/09/07
Ellagic acid rescues motor and cognitive deficits in the R6/2 mouse model of Huntington's disease by lowering mutant huntingtin protein 期刊论文  OAI收割
FOOD & FUNCTION, 2020, 卷号: 11, 期号: 2, 页码: 1334-1348
作者:  
Sun, Xun;  Zhu, Jie;  Sun, Xiao-ying;  Ji, Mei;  Yu, Xiao-lin
  |  收藏  |  浏览/下载:25/0  |  提交时间:2020/05/06
Intravenous immunoglobulin ameliorates motor and cognitive deficits and neuropathology in R6/2 mouse model of Huntington's disease by decreasing mutant huntingtin protein level and normalizing NF-kappa B signaling pathway 期刊论文  OAI收割
BRAIN RESEARCH, 2018, 卷号: 1697, 页码: 21-33
作者:  
Liu, Shu-ying;  Yu, Xiao-lin;  Zhu, Jie;  Liu, Xiang-meng;  Zhang, Yue
  |  收藏  |  浏览/下载:48/0  |  提交时间:2018/10/11
A scFv antibody targeting common oligomeric epitope has potential for treating several amyloidoses 期刊论文  OAI收割
SCIENTIFIC REPORTS, 2016, 卷号: 6, 期号: NOV, 页码: 36631
作者:  
Zha, Jun;  Liu, Xiang-meng;  Zhu, Jie;  Liu, Shu-ying;  Lu, Shuai
收藏  |  浏览/下载:26/0  |  提交时间:2016/12/26
High-dose thalidomide increases the risk of peripheral neuropathy in the treatment of ankylosing spondylitis 期刊论文  OAI收割
Neural Regeneration Research, 2015, 卷号: 10, 期号: 5, 页码: 814-818
作者:  
Xue Hongxia;  Fu Wenyi;  Cui Huadong;  Yang Lili;  Zhang Ning
  |  收藏  |  浏览/下载:24/0  |  提交时间:2021/02/02
active zone stability  Drosophila  neuromuscular junction  dephosphorylation  Liprin-α  Syd-1  PP2A  GSK-3?  living scaffolds  neural tissue engineering  cell transplant  biomaterials  regeneration  neurotrauma  neurodegeneration  axon pathfinding  cell migration  injury  plasticity  neurodegenerative disease  brain  therapy  neuron  microglia  neural progenitor  tissue engineering  neuroregeneration  repair  central nervous system  biomaterial  regenerative medicine  nanotechnology  spinal cord injury  axonal regeneration  exosome  extracellular vesicle  microRNA  microvesicle  nerve gap  neurite outgrowth  peripheral nerve injury  Schwann cell  stem cell  hemodynamic phases  cerebral subarachnoid hemorrhage  metabolic crises  nerve regeneration  hypoxic-ischemic brain damage  ginsenoside Rg1  neural stem cells  cell transplantation  cell differentiation  cognition  nerve reconstruction  neural regeneration  nerve regeneration  brain injury  neuroimaging  functional magnetic resonance imaging  regional homogeneity  apoplexy  subacute  ischemia  participants  healthy  volunteers  brain activity  NSFC grants  neural regeneration  nerve regeneration  brain injury  neuroprotection  cerebral ischemia/reperfusion injury  lateral intracerebroventricular injection  Apelin-13  nerve apoptosis  Bcl-2  caspase-3  NSFC grants  neural regeneration  nerve regeneration  fractalkine  CX3 chemokine receptor 1  neuronal maturation  dendrites  doublecortin  synaptic maturation  newborn neurons  neural regeneration  nerve regeneration  neurodegenerative diseases  Alzheimer′s disease  transgenic animal models  mice  epimedium herb  milkvetch root  kudzuvine root  divalent metal transporter 1  ferroportin 1  neural regeneration  nerve regeneration  microRNA-124  neurogenesis  neuronal survival  Huntington′s disease  SRY-related HMG box transcription factor 9  brain-derived neurotrophic factor  peroxisome proliferator-activated receptor gamma coactivator 1-alpha  mutant huntingtin  nerve regeneration  Ras/Raf/Erk1/2 signaling pathway  spinal cord injury  apoptosis  repair  regulation  inhibition  neural regeneration  nerve regeneration  neurogenic bladder  bibliometric analysis  Web of Science database  visualization analysis  CiteSpace III  citation analysis  neural regeneration  nerve regeneration  sciatic nerve injury  autologous nerve grafting  epineurial suturing  three-dimensional finite element models  load  stress  displacement  neural regeneration  nerve regeneration  brain injury  facial palsy  Bell′s palsy  comparison  methodological quality  therapy  fixed effect model  acupuncture  incomplete recovery  randomized controlled trials  electroacupuncture  NSFC grants  neural regeneration  nerve regeneration  peripheral nerve injury  thalidomide  ankylosing spondylitis  adverse reactions  peripheral neuropathy  treatment  dose  treatment time  age  sex  neural regeneration  Neurology. Diseases of the nervous system  RC346-429  prospective study  
High-dose thalidomide increases the risk of peripheral neuropathy in the treatment of ankylosing spondylitis 期刊论文  OAI收割
Neural Regeneration Research, 2015, 卷号: 10, 期号: 5, 页码: 814-818
作者:  
Xue Hongxia;  Fu Wenyi;  Cui Huadong;  Yang Lili;  Zhang Ning
  |  收藏  |  浏览/下载:27/0  |  提交时间:2021/02/02
active zone stability  Drosophila  neuromuscular junction  dephosphorylation  Liprin-α  Syd-1  PP2A  GSK-3?  living scaffolds  neural tissue engineering  cell transplant  biomaterials  regeneration  neurotrauma  neurodegeneration  axon pathfinding  cell migration  injury  plasticity  neurodegenerative disease  brain  therapy  neuron  microglia  neural progenitor  tissue engineering  neuroregeneration  repair  central nervous system  biomaterial  regenerative medicine  nanotechnology  spinal cord injury  axonal regeneration  exosome  extracellular vesicle  microRNA  microvesicle  nerve gap  neurite outgrowth  peripheral nerve injury  Schwann cell  stem cell  hemodynamic phases  cerebral subarachnoid hemorrhage  metabolic crises  nerve regeneration  hypoxic-ischemic brain damage  ginsenoside Rg1  neural stem cells  cell transplantation  cell differentiation  cognition  nerve reconstruction  neural regeneration  nerve regeneration  brain injury  neuroimaging  functional magnetic resonance imaging  regional homogeneity  apoplexy  subacute  ischemia  participants  healthy  volunteers  brain activity  NSFC grants  neural regeneration  nerve regeneration  brain injury  neuroprotection  cerebral ischemia/reperfusion injury  lateral intracerebroventricular injection  Apelin-13  nerve apoptosis  Bcl-2  caspase-3  NSFC grants  neural regeneration  nerve regeneration  fractalkine  CX3 chemokine receptor 1  neuronal maturation  dendrites  doublecortin  synaptic maturation  newborn neurons  neural regeneration  nerve regeneration  neurodegenerative diseases  Alzheimer′s disease  transgenic animal models  mice  epimedium herb  milkvetch root  kudzuvine root  divalent metal transporter 1  ferroportin 1  neural regeneration  nerve regeneration  microRNA-124  neurogenesis  neuronal survival  Huntington′s disease  SRY-related HMG box transcription factor 9  brain-derived neurotrophic factor  peroxisome proliferator-activated receptor gamma coactivator 1-alpha  mutant huntingtin  nerve regeneration  Ras/Raf/Erk1/2 signaling pathway  spinal cord injury  apoptosis  repair  regulation  inhibition  neural regeneration  nerve regeneration  neurogenic bladder  bibliometric analysis  Web of Science database  visualization analysis  CiteSpace III  citation analysis  neural regeneration  nerve regeneration  sciatic nerve injury  autologous nerve grafting  epineurial suturing  three-dimensional finite element models  load  stress  displacement  neural regeneration  nerve regeneration  brain injury  facial palsy  Bell′s palsy  comparison  methodological quality  therapy  fixed effect model  acupuncture  incomplete recovery  randomized controlled trials  electroacupuncture  NSFC grants  neural regeneration  nerve regeneration  peripheral nerve injury  thalidomide  ankylosing spondylitis  adverse reactions  peripheral neuropathy  treatment  dose  treatment time  age  sex  neural regeneration  Neurology. Diseases of the nervous system  RC346-429  prospective study  
Genome-wide loss of 5-hmC is a novel epigenetic feature of Huntingtons disease 期刊论文  OAI收割
HUMAN MOLECULAR GENETICS, 2013, 卷号: 22, 期号: 18, 页码: 3641-3653
作者:  
Wang, Fengli;  Yang, Yeran;  Lin, Xiwen;  Wang, Jiu-Qiang;  Wu, Yong-Sheng
收藏  |  浏览/下载:37/0  |  提交时间:2013/10/16