中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共18条,第1-10条 帮助

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Design and Synthesis Studies of α-Methylene-γ-butyrolactones Antagonists of GPR52 期刊论文  OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2023, 卷号: 43, 期号: 11, 页码: 3916-3929
作者:  
Shen, Donghang;  Li, Xin;  Guo, Shimeng;  Xie, Xin;  Nan, Fajun
  |  收藏  |  浏览/下载:13/0  |  提交时间:2024/02/27
GPR52 Antagonist Reduces Huntingtin Levels and Ameliorates Huntington's Disease-Related Phenotypes 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 2, 页码: 941-957
作者:  
Wang, Congcong;  Zhang, Yu-Fang;  Guo, Shimeng;  Zhao, Quan;  Zeng, Yanping
  |  收藏  |  浏览/下载:17/0  |  提交时间:2021/05/24
Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 卷号: 42, 期号: 10, 页码: 1556-1566
作者:  
Li, Xiao-jing;  Zhang, Yuan-yuan;  Fu, Yu-hua;  Zhang, Hao;  Li, He-xuan
  |  收藏  |  浏览/下载:12/0  |  提交时间:2024/03/21
应用鞣花酸治疗亨廷顿舞蹈病转基因小鼠的研究 学位论文  OAI收割
: 中国科学院大学, 2020
作者:  
孙勋
  |  收藏  |  浏览/下载:29/0  |  提交时间:2021/09/07
Ellagic acid rescues motor and cognitive deficits in the R6/2 mouse model of Huntington's disease by lowering mutant huntingtin protein 期刊论文  OAI收割
FOOD & FUNCTION, 2020, 卷号: 11, 期号: 2, 页码: 1334-1348
作者:  
Sun, Xun;  Zhu, Jie;  Sun, Xiao-ying;  Ji, Mei;  Yu, Xiao-lin
  |  收藏  |  浏览/下载:25/0  |  提交时间:2020/05/06
Intravenous immunoglobulin ameliorates motor and cognitive deficits and neuropathology in R6/2 mouse model of Huntington's disease by decreasing mutant huntingtin protein level and normalizing NF-kappa B signaling pathway 期刊论文  OAI收割
BRAIN RESEARCH, 2018, 卷号: 1697, 页码: 21-33
作者:  
Liu, Shu-ying;  Yu, Xiao-lin;  Zhu, Jie;  Liu, Xiang-meng;  Zhang, Yue
  |  收藏  |  浏览/下载:47/0  |  提交时间:2018/10/11
PolyQ-expanded huntingtin and ataxin-3 sequester ubiquitin adaptors hHR23B and UBQLN2 into aggregates via conjugated ubiquitin 期刊论文  OAI收割
FASEB JOURNAL, 2018, 卷号: 32, 期号: 6, 页码: 2923-2933
作者:  
Yang, Hui;  Yue, Hong-Wei;  He, Wen-Tian;  Hong, Jun-Ye;  Jiang, Lei-Lei
  |  收藏  |  浏览/下载:26/0  |  提交时间:2019/04/28
A scFv antibody targeting common oligomeric epitope has potential for treating several amyloidoses 期刊论文  OAI收割
SCIENTIFIC REPORTS, 2016, 卷号: 6, 期号: NOV, 页码: 36631
作者:  
Zha, Jun;  Liu, Xiang-meng;  Zhu, Jie;  Liu, Shu-ying;  Lu, Shuai
收藏  |  浏览/下载:25/0  |  提交时间:2016/12/26
Aggregation of polyglutamine-expanded ataxin-3 sequesters its specific interacting partners into inclusions: Implication in a loss-of-function pathology 期刊论文  OAI收割
SCIENTIFIC REPORTS, 2014, 卷号: 4, 期号: 1, 页码: 6410-6410
作者:  
Yang, H;  Li, JJ;  Liu, S;  Zhao, J;  Jiang, YJ
收藏  |  浏览/下载:37/0  |  提交时间:2015/07/22
Autoinhibitory Structure of the WW Domain of HYPB/SETD2 Regulates Its Interaction with the Proline-Rich Region of Huntingtin 期刊论文  OAI收割
STRUCTURE, 2014, 卷号: 22, 期号: 3, 页码: 378-386
作者:  
Gao, YG;  Yang, H;  Zhao, J;  Jiang, YJ;  Hu, HY
收藏  |  浏览/下载:20/0  |  提交时间:2015/07/22