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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [20]
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期刊论文 [25]
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PRMT1 Inhibition Activates the Interferon Pathway to Potentiate Antitumor Immunity and Enhance Checkpoint Blockade Efficacy in Melanoma
期刊论文
OAI收割
CANCER RESEARCH, 2024, 卷号: 84, 期号: 3, 页码: 419-433
作者:
Tao, Hongru
;
Jin, Chen
;
Zhou, Liyuan
;
Deng, Zhenzhong
;
Li, Xiao
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/04/09
Spermine is a natural suppressor of AR signaling in castration-resistant prostate cancer
期刊论文
OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 7, 页码: 24
作者:
Li, Xiao
;
Li, Fei
;
Ye, Fei
;
Guo, Haotian
;
Chen, Wentao
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
Inhibition of protein arginine methyltransferase 1 alleviates liver fibrosis by attenuating the activation of hepatic stellate cells in mice
期刊论文
OAI收割
FASEB JOURNAL, 2022, 卷号: 36, 期号: 9, 页码: 14
作者:
Yan, Fang-Zhi
;
Qian, Hui
;
Liu, Fang
;
Ding, Chen-Hong
;
Liu, Shu-Qing
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/09/30
hepatic stellate cell
inflammation
inhibitor
liver fibrosis
protein arginine methyltransferase 1
The methyltransferase PRMT1 regulates γ-globin translation
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2021, 卷号: 296, 页码: 100417
作者:
Wang, Ying
;
Li, Xinyu
;
Ge, Jingru
;
Liu, Ming
;
Pang, Xiaming
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/03/21
PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma
期刊论文
OAI收割
THERANOSTICS, 2021, 卷号: 11, 期号: 11, 页码: 5387-5403
作者:
Wang, Jianfeng
;
Wang, Chen
;
Xu, Pan
;
Li, Xiao
;
Lu, Yongning
  |  
收藏
  |  
浏览/下载:77/0
  |  
提交时间:2021/05/24
clear cell renal cell carcinoma
protein arginine methyltransferase 1
therapeutic
lipocalin2 (LCN2)
sunitinib
PRMT1 promotes neuroblastoma cell survival through ATF5
期刊论文
OAI收割
ONCOGENESIS, 2020, 卷号: 9, 期号: 5
作者:
Hua Zhong-Yan
;
Hansen Jeanne N.
;
He Miao
;
Dai Shang-Kun
;
Choi Yoonjung
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/10/26
Rational Design, synthesis and biological evaluation of novel triazole derivatives as potent and selective PRMT5 inhibitors with antitumor activity
期刊论文
OAI收割
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 8, 页码: 775-785
作者:
Zhu, Kongkai
;
Shao, Jingwei
;
Tao, Hongrui
;
Yan, Xue
;
Luo, Cheng
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
PRMT5 inhibitor
Anti-proliferative
Cellular target validation
Design and synthesis
Reduced asymmetric dimethylarginine accumulation through inhibition of the type I protein arginine methyltransferases promotes renal fibrosis in obstructed kidneys
期刊论文
OAI收割
FASEB JOURNAL, 2019, 卷号: 33, 期号: 6, 页码: 6948-6956
作者:
Wu, Ming
;
Lin, Pinglan
;
Li, Lin
;
Chen, Dongping
;
Yang, Xuejun
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/03/21
PRMT1
ADMA
NO
CKD
A patent review of arginine methyltransferase inhibitors (2010-2018)
期刊论文
OAI收割
EXPERT OPINION ON THERAPEUTIC PATENTS, 2019, 卷号: 29, 期号: 2, 页码: 97-114
作者:
Li, Xiao
;
Wang, Chen
;
Jiang, Hao
;
Luo, Cheng
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
Arginine methylation
Protein arginine methyltransferases (PRMTs)
small molecule inhibitors
drug research and development
Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3693-3699
作者:
Zhu, Kongkai
;
Song, Jia-Li
;
Tao, Hong-Rui
;
Cheng, Zhi-Qiang
;
Jiang, Cheng-Shi
  |  
收藏
  |  
浏览/下载:100/0
  |  
提交时间:2019/01/08
Pharmacophore combination
Isoquinoline
PRMT5 inhibitor
Molecular docking
Molecular dynamics simulation