中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [499]
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Amlodipine inhibits Synaptotagmin-4's oncogenic activity on gastric cancer proliferation by targeting calcium signaling
期刊论文
OAI收割
FUNCTIONAL & INTEGRATIVE GENOMICS, 2024, 卷号: 24, 期号: 3, 页码: 14
作者:
Huang, Wen
;
Yang, Shuo
;
Deng, Minying
;
Luo, Rongkui
;
Liang, Huaiyu
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/22
Gastric cancer
synaptotagmin-4
Calcium ion channel
Mitogen-activated protein kinase signaling pathway
Amlodipine
Tumor-targeted PROTAC prodrug nanoplatform enables precise protein degradation and combination cancer therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12
作者:
Zou, Zhi-feng
;
Yang, Lei
;
Nie, Hui-jun
;
Gao, Jing
;
Lei, Shu-min
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
proteolysis-targeting chimeras
tumor-targeted delivery
precise protein degradation
combination therapy
triple-negative breast cancer
Enhancing Specific Fluorescence In Situ Hybridization with Quantum Dots for Single-Molecule RNA Imaging in Formalin-Fixed Paraffin-Embedded Tumor Tissues
期刊论文
OAI收割
ACS NANO, 2024, 卷号: 18, 期号: 14, 页码: 9958-9968
作者:
Zhao, Zeyin
;
Jiang, Mengyuan
;
He, Chen
;
Yin, Wenjuan
;
Feng, Yawei
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/05/07
single molecule
split-FISH
quantum dots
RNA imaging
quantification
FFPE
clinical samples
diagnostic pathology
DNA-PK-Mediated Cytoplasmic DNA Sensing Stimulates Glycolysis to Promote Lung Squamous Cell Carcinoma Malignancy and Chemoresistance
期刊论文
OAI收割
CANCER RESEARCH, 2024, 卷号: 84, 期号: 5, 页码: 688-702
作者:
Wang, Hui
;
Zhang, Yanyang
;
Tian, Yu
;
Yang, Wanlin
;
Wang, Yan
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/07
Functional structural domain synthesis of anti-pancreatic carcinoma pectin-like polysaccharide RN1
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2024, 卷号: 327, 页码: 11
作者:
Cai, Deqin
;
He, Fei
;
Wu, Shengjie
;
Wang, Zixuan
;
Bian, Ya
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/02/19
Polysaccharide
Pectin
Functional structural domain
Pancreatic cancer
Glycan synthesis
RN1
PROTAC Prodrug-Integrated Nanosensitizer for Potentiating Radiation Therapy of Cancer
期刊论文
OAI收割
ADVANCED MATERIALS, 2024, 页码: 12
作者:
Zhang, Shunan
;
Lai, Yi
;
Pan, Jiaxing
;
Saeed, Madiha
;
Li, Shiqin
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/04/09
active tumor targeting
nanosensitizer
PROTAC prodrug
radiation therapy
tumor microenvironment
Single-cell transcriptomics reveals the role of antigen presentation in liver metastatic breast cancer
期刊论文
OAI收割
ISCIENCE, 2024, 卷号: 27, 期号: 2, 页码: 20
作者:
Wang, Xiaoshuang
;
Zhou, Yan
;
Wu, Zhongen
;
Xie, Cao
;
Xu, Weiqi
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Discovery of Novel PROTAC Degraders of p300/CBP as Potential Therapeutics for Hepatocellular Carcinoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2466-2486
作者:
Chang, Qi
;
Li, Jiayi
;
Deng, Yue
;
Zhou, Ruilin
;
Wang, Bingwei
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/03/25
Synthesis and Biological Evaluation of β-Lactam Derivatives Targeting Speckle-Type POZ Protein (SPOP)
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 15, 期号: 2, 页码: 270-279
作者:
Zhou, Chenmao
;
Hao, Xinyue
;
Chen, Zhengyang
;
Zhang, Runze
;
Zhou, Qian
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/03/13
Speckle-type POZ protein (SPOP)
SPOP inhibitors
Clear cell renal cell carcinoma (ccRCC)
Structure-activityrelationship (SAR)
Stereoconvergent and Chemoenzymatic Synthesis of Tumor-Associated Glycolipid Disialosyl Globopentaosylceramide for Probing the Binding Affinity of Siglec-7
期刊论文
OAI收割
ACS CENTRAL SCIENCE, 2024, 卷号: 10, 期号: 2, 页码: 417-425
作者:
Liu, Yating
;
Yan, Mengkun
;
Wang, Minghui
;
Luo, Shiwei
;
Wang, Shasha
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/25