机构

• 上海药物研究所 [7]
• 合肥物质科学研究院 [3]
• 上海生物化学与细胞生... [1]
• 烟台海岸带研究所 [1]

采集方式

• OAI收割 [12]

内容类型

• 期刊论文 [12]

发表日期

• 2023 [2]
• 2022 [3]
• 2021 [4]
• 2019 [2]
• 2018 [1]

学科主题

筛选

浏览/检索结果: 共12条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 Discovery of HCD3514 as a potent EGFR inhibitor against C797S mutation in vitro and in vivo 期刊论文  OAI收割 JOURNAL OF CANCER, 2023, 卷号: 14, 期号: 1, 页码: 152-162 作者:  Lai, Mengzhen;  Zhang, Tao;  Chen, Hao;  Song, Peiran;  Tong, Linjiang   |  收藏  |  浏览/下载：111/0  |  提交时间：2023/04/10 fourth-generation EGFR inhibitor  EGFRC797S mutation  NSCLC  drug resistance  small molecular inhibitor   Results of the phase IIa study to evaluate the efficacy and safety of rezivertinib (BPI-7711) for the first-line treatment of locally advanced or metastatic EGFR mutation from a phase I 期刊论文  OAI收割 BMC MEDICINE, 2023, 卷号: 21, 期号: 1 作者:  Yuankai Shi;  Jianying Zhou;  Yanqiu Zhao;  Bo Zhu;  Liangming Zhang   |  收藏  |  浏览/下载：0/0  |  提交时间：2024/05/07 The effect of EGFR-TKIs on survival in advanced non-small-cell lung cancer with EGFR mutations: A real-world study 期刊论文  OAI收割 CANCER MEDICINE, 2022 作者:  Yu, Xiaoqing;  Si, Jinfei;  Wei, Jingwen;  Wang, Yanling;  Sun, Yan   |  收藏  |  浏览/下载：119/0  |  提交时间：2022/12/23 EGFR-TKIs  non-small cell lung cancer (NSCLC)  real-world study  survival outcome   A Phase 2 Study of Befotertinib in Patients with EGFR T790M Mutated NSCLC after Prior EGFR TKIs 期刊论文  OAI收割 JOURNAL OF THORACIC ONCOLOGY, 2022, 卷号: 17 作者:  Lu, S.;  Zhang, Y.;  Zhang, G.;  Zhou, J.;  Cang, S.   |  收藏  |  浏览/下载：104/0  |  提交时间：2022/12/23 third-generation EGFR-TKI  befotertinib  T790M   HER2 exon 20 insertion mutations in lung adenocarcinoma with leptomeningeal metastasis: a case report and response to poziotinib 期刊论文  OAI收割 ANNALS OF PALLIATIVE MEDICINE, 2022, 卷号: 11 作者:  Fan, Ying;  Qin, Jing;  Han, Na;  Lu, Hongyang   |  收藏  |  浏览/下载：15/0  |  提交时间：2022/12/23 Leptomeningeal metastasis (LM)  cerebrospinal fluid  HER2 exon 20 insertion mutations  poziotinib  case report   LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文  OAI收割 CANCER SCIENCE, 2021, 页码: 12 作者:  Liu, Yingqiang;  Lai, Mengzhen;  Li, Shan;  Wang, Yanan;  Feng, Fang   |  收藏  |  浏览/下载：87/0  |  提交时间：2022/01/18 C797S  epidermal growth factor receptor  fourth-generation EGFR TKI  non-small cell lung cancer  osimertinib resistance   Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10 作者:  Zou, Hui-xi;  Zhang, Yu-feng;  Zhong, Da-fang;  Jiang, Yong;  Liu, Fei   |  收藏  |  浏览/下载：76/0  |  提交时间：2022/01/04 furmonertinib  autoinduction  food effect  alkaline phosphatase  body weight  pharmacokinetics  modeling and simulation  NSCLC   Third-generation EGFR inhibitor HS-10296 in combination with famitinib, a multi-targeted tyrosine kinase inhibitor, exerts synergistic antitumor effects through enhanced inhibition of downstream signaling in EGFR-mutant non-small cell lung cancer cells 期刊论文  OAI收割 THORACIC CANCER, 2021, 页码: 9 作者:  Zhang, Mi;  Quan, Haitian;  Fu, Li;  Li, Yun;  Fu, Haoyu   |  收藏  |  浏览/下载：60/0  |  提交时间：2021/05/24 EGFR‐  mutant non‐  small cell lung cancer  famitinib  HS‐  10296  multi‐  targeted tyrosine kinase inhibitor  third‐  generation EGFR inhibitor   Biomimetic codelivery overcomes osimertinib-resistant NSCLC and brain metastasis via macrophage-mediated innate immunity 期刊论文  OAI收割 JOURNAL OF CONTROLLED RELEASE, 2021, 卷号: 329, 页码: 1249-1261 作者:  Zhao, Pengfei;  Zhang, Jiaxin;  Wu, Aihua;  Zhang, Meng;  Zhao, Yuge   |  收藏  |  浏览/下载：42/0  |  提交时间：2021/05/24 Brain targeting delivery  Tumor-associated macrophage  Osimertinib resistance  Brain metastasis  Innate immunity  Combination therapy   Discovery of a novel third generation EGFR TKI and identification of its potential mechanism of resistance 期刊论文  OAI收割 CANCER RESEARCH, 2019, 卷号: 79, 期号: 13, 页码: 2 作者:  Zhang, Tao;  Qu, Rong;  Chen, Chengbin;  Tong, Linjiang;  Feng, Fang   |  收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01