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Design, Synthesis, and Pharmacological Evaluation of Quinazoline and Quinoline Derivatives as Potent ENPP1 Inhibitors for Cancer Immunotherapy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 18
作者:
He, Jie
;
Ma, Xiaoyu
;
Sun, Jia
;
Chen, Manman
;
Xu, Lan
  |  
收藏
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浏览/下载:8/0
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提交时间:2025/04/01
Discovery of Urea Derivatives of Celastrol as Selective Peroxiredoxin 1 Inhibitors against Colorectal Cancer Cells
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 9, 页码: 7176-7196
作者:
Li, Yang
;
Zhu, Yuyuan
;
Shang, Fan-Fan
;
Xu, Lin
;
Jiang, Defang
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2024/06/27
Design, Synthesis, and Pharmacological Evaluation of Spiro[carbazole-3,3′-pyrrolidine] Derivatives as cGAS Inhibitors for Treatment of Acute Lung Injury
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 24
作者:
Chen, Mingjie
;
Lei, Shuyue
;
Zhou, Zihua
;
Wang, Meng
;
Feng, Chunlan
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2024/05/22
Design, Synthesis, and Pharmacological Evaluation of Isoindoline Analogues as New HPK1 Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 23, 页码: 16201-16221
作者:
Xie, Chenghu
;
Liu, Bo
;
Song, Zilan
;
Yang, Ye
;
Dai, Mengdi
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2024/02/27
Photochemically controlled activation of STING by CAIX-targeting photocaged agonists to suppress tumor cell growth
期刊论文
OAI收割
CHEMICAL SCIENCE, 2023, 卷号: 14, 期号: 22, 页码: 5956-5964
作者:
Ding, Chunyong
;
Du, Mengyan
;
Xiong, Zhi
;
Wang, Xue
;
Li, Hongji
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2023/10/17
High temperature tribological behaviors of MoAlB ceramic from 800 to 1200 ℃
期刊论文
OAI收割
Tribology International, 2023, 卷号: 185, 期号: 108522, 页码: 1-10
作者:
Yu ZG(于增光)
;
Chen J(陈娇)
;
Cheng J(程军)
;
Zhu SY(朱圣宇)
;
Tan H(谈辉)
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/12/04
Celastrol suppresses colorectal cancer via covalent targeting peroxiredoxin 1
期刊论文
OAI收割
Signal Transduction and Targeted Therapy, 2023, 卷号: 8, 期号: 3, 页码: 1159-1174
作者:
Xu, Heng
;
Zhao, Hongfang
;
Ding, Chunyong
;
Jiang, Defang
;
Zhao, Zijie
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/03/27
Acid-Ionizable Iron Nanoadjuvant Augments STING Activation for Personalized Vaccination Immunotherapy of Cancer
期刊论文
OAI收割
ADVANCED MATERIALS, 2023, 页码: 15
作者:
Chen, Fangmin
;
Li, Tianliang
;
Zhang, Huijuan
;
Saeed, Madiha
;
Liu, Xiaoying
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2023/04/10
acid-ionizable nanoadjuvants
cancer vaccines
iron oxide nanoparticles
personalized immunotherapy
STING cascade activation
Structure-Activity relationship study of benzothiophene oxobutanoic acid analogues leading to novel stimulator of interferon gene (STING) agonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 241, 页码: 16
作者:
Shen, Ancheng
;
Li, Xiyuan
;
Zhang, Yan
;
Ma, Jing
;
Xiao, Ruoxuan
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2023/04/10
Innate immunity
STING Agonists
Structural modification
Immuno-oncology
Design, synthesis and pharmacological evaluation of new PARP1 inhibitors by merging pharmacophores of olaparib and the natural product alantolactone
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 240, 页码: 114574
作者:
Kayumov, Muzaffar
;
Jia, Li
;
Pardaev, Azizbek
;
Song, Shan-Shan
;
Mirzaakhmedov, Sharafitdin
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2024/03/21
PARP1
Olaparib
Alantolactone
Syntheticlethality
BRCA1/2mutant