中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [13]
地理科学与资源研究所 [8]
上海有机化学研究所 [7]
自动化研究所 [6]
植物研究所 [6]
兰州化学物理研究所 [6]
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OAI收割 [72]
内容类型
期刊论文 [70]
会议论文 [1]
标准 [1]
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2024 [4]
2023 [9]
2022 [9]
2021 [5]
2020 [9]
2019 [5]
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天然产物有机化学 [6]
Plant Scie... [3]
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浏览/检索结果:
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Discovery of Novel Nonpeptidic and Noncovalent Small Molecule 3CL
pro
Inhibitors as anti-SARS-CoV-2 Drug Candidate
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12760-12783
作者:
Jiang, Zhidong
;
Feng, Bo
;
Chen, Lu
;
Nie, Tianqing
;
Chen, Shizhao
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/09/26
Integrating a Physical Model with Multi-Objective Optimization for the Design of Optical Angle Nano-Positioning Mechanism
期刊论文
OAI收割
APPLIED SCIENCES-BASEL, 2024, 卷号: 14, 期号: 9
作者:
Jiang, Bo
;
Dong, Yiming
;
Zhang, Zijie
;
Li, Xiangyu
;
Wei, Yuxuan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/08/22
nano-positioning mechanisms
synchrotron radiation facility
multi-objective optimization
Mapping the potential distribution of Asian elephants: Implications for conservation and human-elephant conflict mitigation in South and Southeast Asia
期刊论文
OAI收割
ECOLOGICAL INFORMATICS, 2024, 卷号: 80, 页码: 102518
作者:
Xu, Haixia
;
Jiang, Luguang
;
Liu, Ye
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/09/19
Asian elephant
Maximum entropy
Environmental features
Population characteristics
Assessing the Accuracy and Consistency of Cropland Products in the Middle Yangtze Plain
期刊论文
OAI收割
LAND, 2024, 卷号: 13, 期号: 3, 页码: 14
作者:
Xu, Haixia
;
Jiang, Luguang
;
Liu, Ye
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/05/06
cropland distribution
Middle Yangtze Plain
GLAD (Global Land Analysis & Discovery)
AGLC (Annual Global Land Cover)
CLCD (China Land Cover Dataset)
CACD (China's Annual Cropland Dataset)
Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15
作者:
Jiang, Xiangrui
;
Su, Haixia
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2024/03/25
Design, synthesis and biological evaluation of peptidomimetic benzothiazolyl ketones as 3CLpro inhibitors against SARS-CoV-2
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 13
作者:
Yang, Hanxi
;
You, Mengyuan
;
Shu, Xiaoyang
;
Zhen, Jingyao
;
Zhu, Mengwei
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/10/17
Peptidomimetics
Benzothiazolyl ketone
3CLpro inhibitor
Pharmacokinetic properties
SARS-CoV-2
Discovery of novel non-peptidic and non-covalent small-molecule 3CL(pro) inhibitors as potential candidate for COVID-19 treatment
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 4
作者:
Jiang, Zhidong
;
Feng, Bo
;
Zhang, Yumin
;
Nie, Tianqing
;
Liu, Hong
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/10/17
Design, synthesis and biological evaluation of covalent peptidomimetic 3CL protease inhibitors containing nitrile moiety
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 87, 页码: 12
作者:
Zhu, Mengwei
;
Fu, Tiantian
;
You, Mengyuan
;
Cao, Junyuan
;
Yang, Hanxi
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
COVID-19
SARS-CoV-2
3CL protease
Nirmatrelvir
Peptidomimetic inhibitors
Spatiotemporal and global profiling of DNA-protein interactions enables discovery of low-affinity transcription factors
期刊论文
OAI收割
NATURE CHEMISTRY, 2023, 页码: 18
作者:
Guo, An-Di
;
Yan, Ke-Nian
;
Hu, Hao
;
Zhai, Linhui
;
Hu, Teng-Fei
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/10/17
Variation in Vegetation Quality of Terrestrial Ecosystems in China: Coupling Analysis Based on Remote Sensing and Typical Stations Monitoring Data
期刊论文
OAI收割
REMOTE SENSING, 2023, 卷号: 15, 期号: 9, 页码: 2276
作者:
Jiang, Luguang
;
Liu, Ye
;
Xu, Haixia
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/06/10
vegetation quality
terrestrial ecosystem
typical stations
remote sensing retrieval data
spatio-temporal change