中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
南海海洋研究所 [7]
上海药物研究所 [6]
过程工程研究所 [3]
海洋研究所 [3]
广州生物医药与健康研... [2]
昆明植物研究所 [2]
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期刊论文 [22]
专利 [3]
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2024 [2]
2023 [3]
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Biochemist... [2]
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Discovery of Novel 1-Phenylpiperidine Urea-Containing Derivatives Inhibiting
β
-Catenin/BCL9 Interaction and Exerting Antitumor Efficacy through the Activation of Antigen Presentation of cDC1 Cells
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 36
作者:
Zhu, Wenhua
;
Liu, Cuiting
;
Xi, Kang
;
Li, Anqi
;
Shen, Li-an
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/08/20
Synthesis and biological evaluation of 4-imidazolidinone-containing compounds as potent inhibitors of the MDM2/p53 interaction
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 270, 页码: 16
作者:
Lin, Zhitong
;
Liu, Chen
;
Yan, Ziqin
;
Cheng, Jing
;
Wang, Xiancheng
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/06/27
MDM2
p53
p21
Imidazolidinone
Apoptosis
Structure basis of two nanobodies neutralizing SARS-CoV-2 Omicron variant by targeting ultra-conservative epitopes
期刊论文
OAI收割
JOURNAL OF STRUCTURAL BIOLOGY, 2023, 卷号: 215, 期号: 3, 页码: 9
作者:
Sun, Zengchao
;
Wang, Lu
;
Li, Lingyun
;
Sun, Yili
;
Zhang, Daizhou
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
SARS-CoV-2 virus
Receptor -binding domain
Nanobody
Crystal structure
Conservative binding epitope
Bi-paratopic nanobodies
Synthesis and Biological Evaluation of Sclareolide-Indole Conjugates and Their Derivatives
期刊论文
OAI收割
MOLECULES, 2023, 卷号: 28, 期号: 4, 页码: 1737
作者:
Cheng, Ying
;
Lyu, Xilin
;
Liu, Chen
;
Wang, Xiancheng
;
Cheng, Jing
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/27
sclareolide
indole
polyphenol
acetal
antitumor activity
Guvermectin Biosynthesis Revealing the Key Role of a Phosphoribohydrolase and Structural Insight into the Active Glutamate of a Noncanonical Adenine Phosphoribosyltransferase
期刊论文
OAI收割
ACS CHEMICAL BIOLOGY, 2023
作者:
Liu,Chongxi
;
Wang,Zhiyan
;
Chen,Yin
;
Yan,Yijun
;
Li,Lei
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/07/10
CRYSTAL-STRUCTURE
GENOMES
A chemical perspective on the modulation of TEAD transcriptional activities: Recent progress, challenges, and opportunities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243, 页码: 31
作者:
Lou, Jianfeng
;
Lu, Yuhang
;
Cheng, Jing
;
Zhou, Feilong
;
Yan, Ziqin
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/12/13
TEAD
YAP
Palmitoylation
Protein-protein interaction
Covalent inhibitor
Regulation on both pore structure and pressure-resistant property of uniform agarose microspheres for high-resolution chromatography
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY A, 2022, 卷号: 1681, 页码: 13
作者:
Zhao, Lan
;
Che, Xiangjing
;
Huang, Yongdong
;
Zhu, Kai
;
Du, Yuxiang
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2023/02/24
Agarose microspheres
Uniform
Pore structure
Pressure-resistant property
High-resolution chromatography
Preparation and structural regulation of macroporous agarose microspheres for highly efficient adsorption of giant biomolecules
期刊论文
OAI收割
COLLOID AND POLYMER SCIENCE, 2022, 卷号: 300, 期号: 6, 页码: 691-705
作者:
Zhao, Lan
;
Huang, Lan
;
Huang, Yongdong
;
Zhu, Kai
;
Che, Xiangjing
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2023/02/24
Macroporous agarose microspheres
Micellar swelling method
Pore-forming
Chromatographic media
Adsorption
Structure-Based Discovery of MDM2/4 Dual Inhibitors that Exert Antitumor Activities against MDM4-Overexpressing Cancer Cells
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 8, 页码: 6207-6230
作者:
Zhang, Shiyan
;
Yan, Ziqin
;
Li, Yafang
;
Gong, Yang
;
Lyu, Xilin
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/08/16
Novel Plant Growth Regulator Guvermectin from Plant Growth- Rhizobacteria Boosts Biomass and Grain Yield in Rice
期刊论文
OAI收割
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2022
作者:
Liu, Chongxi
;
Bai, Lu
;
Cao, Peng
;
Li, Shanshan
;
Huang, Sheng-Xiong
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/08/21
guvermectin
plant growth regulator
plant growth-promoting rhizobacteria
rice yield
transcriptome
APICAL HOOK DEVELOPMENT
SMALL-AUXIN
H+-ATPASES
ROOT
GENE
INHIBITION
ETHYLENE