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Chinese Academy of Sciences Institutional Repositories Grid
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Pharmacokinetics, mass balance, and metabolism of [
14
C]PLB1004, a selective and irreversible EGFR-TKI in humans
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2025, 卷号: 95, 期号: 1, 页码: 14
作者:
Liu, Donghui
;
Li, Qian
;
Yan, Shu
;
Zhang, Xinyue
;
Li, Weiqiang
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2025/04/01
PLB1004
[C-14]PLB1004
Radioactivity
Mass balance
EGFR-TKI
Biosynthesized CoS by
Shewanella
algae
for efficient organic pollutants degradation via peroxymonosulfate activation: Augmented catalytic activity and minimized environmental toxicity
期刊论文
OAI收割
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY, 2025, 卷号: 235, 页码: 197-208
作者:
Yang, Jing
;
Zhai, Xiaofan
;
Zhang, Shiqi
;
Ju, Peng
;
Li, Zihao
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2025/07/11
Biosynthesis
Cobalt-based catalyst
Rhodamine B
Tetracycline
Peroxymonosulfate activation
Construction of colorimetric/fluorescent dual-signal probes for the detection of
β
-galactosidase in senescent cells
期刊论文
OAI收割
DYES AND PIGMENTS, 2025, 卷号: 242, 页码: 8
作者:
Dong, Lei
;
Sun, Lu-Lu
;
Li, Wen-Jia
;
Xing, Jing
;
Tan, Mingchao
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
beta-Galactosidase
Fluorescence sensing
Cell senescence
Dislocation loops enhance wear resistance in Ti2Zr0.75NbVx lightweight refractory medium-entropy alloys via high thermal conductivity-promoted oxide film formation
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF REFRACTORY METALS & HARD MATERIALS, 2025, 卷号: 132, 页码: 13
作者:
Zhang, Xinlong
;
Xiong, Zixian
;
Li, Lianning
;
Feng, Zhiyu
;
Wu, Bingzhao
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/08/18
Lightweight refractory medium-entropy alloys
Dislocation loops
Thermal conductivity
Wear resistance
Molecular dynamics simulation
Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17
作者:
Mo, Jun
;
Wang, Yuxian
;
Pan, Youlu
;
Xiao, Qitao
;
Zhao, Jinyi
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/08/20
Menin
High binding affinity
Anti-proliferation activity
AML
Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CL
pro
inhibitors against SARS-CoV-2
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 11
作者:
Guma, Samuel Desta
;
Song, Kang
;
Sun, Haiguo
;
Yang, Lei
;
Zhou, Zhaoyin
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
SARS-CoV-2
3CL(pro) inhibitors
Thioamide derivatives
Spiropyrrolidine derivatives
Nirmatrelvir
HCoV-OC43
Antiviral
Metabolic stability
The deubiquitinase USP2 preserves intestinal barrier through the TRAF6/ NF-κB/MLCK/MLC signaling in ulcerative colitis
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2025, 卷号: 162, 页码: 12
作者:
Zhou, Ruochen
;
Cui, Yuanyuan
;
Wang, Weihao
;
Qu, Yidan
;
Zhang, Gaojie
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/08/20
Ubiquitin-specific protease 2
Ulcerative colitis
Intestinal epithelial cell
Tight junction
Discovery of indole derivatives as STING degraders
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 21
作者:
An, Yuxiang
;
Zhang, Yan
;
Luo, Xin
;
Lan, Yaohan
;
Geng, Meiyu
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Autoimmune diseases
Degrader
Inflammatory
PROTAC
STING
Environmental thresholds triggering changes in above and belowground biomass carbon in China
期刊论文
OAI收割
GLOBAL ECOLOGY AND CONSERVATION, 2025, 卷号: 61, 页码: 18
作者:
Zhang, Xin
;
Zhang, Shihang
;
Zhou, Jun
;
Fan, Jianrong
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/18
Aboveground biomass carbon
Belowground biomass carbon
Environmental factors
SSP5-8.5 scenarios
Spatial analysis
Climate change
Inhibition of α-synuclein aggregation by MCC950 attenuates dopaminergic neuronal damage in MN9D cells
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACOLOGY, 2025, 卷号: 1001, 页码: 10
作者:
Gao, Huiwen
;
Liang, Yingneng
;
Wang, Mengfei
;
Li, Wen
;
Zheng, Wei
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/08/20
alpha-synuclein
MCC950
Parkinson's disease
Neuroprotection