中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Construction of colorimetric/fluorescent dual-signal probes for the detection of
β
-galactosidase in senescent cells
期刊论文
OAI收割
DYES AND PIGMENTS, 2025, 卷号: 242, 页码: 8
作者:
Dong, Lei
;
Sun, Lu-Lu
;
Li, Wen-Jia
;
Xing, Jing
;
Tan, Mingchao
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
beta-Galactosidase
Fluorescence sensing
Cell senescence
Design, synthesis and structure-activity relationship studies of novel macrocyclic 2,4-diaminopyrimidines as HPK1 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 12
作者:
Wu, Feifei
;
Sun, Jiaqi
;
Xu, Mingyang
;
Li, Huiyu
;
Wei, Jiarui
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Macrocycle
Kinase
Inhibitors
HPK1
Cancer immunotherapy
Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CL
pro
inhibitors against SARS-CoV-2
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 11
作者:
Guma, Samuel Desta
;
Song, Kang
;
Sun, Haiguo
;
Yang, Lei
;
Zhou, Zhaoyin
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
SARS-CoV-2
3CL(pro) inhibitors
Thioamide derivatives
Spiropyrrolidine derivatives
Nirmatrelvir
HCoV-OC43
Antiviral
Metabolic stability
Discovery of indole derivatives as STING degraders
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 21
作者:
An, Yuxiang
;
Zhang, Yan
;
Luo, Xin
;
Lan, Yaohan
;
Geng, Meiyu
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Autoimmune diseases
Degrader
Inflammatory
PROTAC
STING
Immunosuppressive nitrogen-containing triterpenoid saponins from
Mussaenda
erosa
and the therapeutic efficacy of heinsiagenin A in a murine lupus erythematosus model
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 11
作者:
Xu, Yidan
;
Xiang, Mai
;
Chang, Yuan
;
Chen, Zhenhua
;
Zhang, Rujun
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Mussaenda erosa
Nitrogen-containing triterpenoid saponins
Immunosuppressive activity
Autoimmune diseases
Heinsiagenin A
Spectroastrometry and Reverberation Mapping of Active Galactic Nuclei. II. Measuring Geometric Distances and Black Hole Masses of Four Nearby Quasars
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2025, 卷号: 988, 期号: 1
作者:
Li, Yan-Rong
;
Shangguan, Jinyi
;
Wang, Jian-Min
;
Davies, Ric
;
Santos, Daryl J. D.
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2025/07/21
Linaggrenoids A-I, structurally diverse lindenane sesquiterpenoids with anti-hepatic fibrosis effects from
Lindera aggregata
期刊论文
OAI收割
PHYTOCHEMISTRY, 2025, 卷号: 235, 页码: 10
作者:
Li, Wen-Xian
;
Gan, Lu
;
Liao, Yi-Ling
;
Wu, Yu-Wei
;
Zhang, Bai-Hui
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/05/27
Lindera aggregata
Lauraceae
Lindenane sesquiterpenoid
Anti-hepatic fibrosis activity
Synthesis and biological evaluation of amino-conjugated bile acid derivatives against non-alcoholic steatohepatitis
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 122, 页码: 6
作者:
Wu, Zhitao
;
Zhang, Mingge
;
Yan, Meng Kun
;
Li, Chenyue
;
Pan, Guoyu
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/05/27
Non-alcoholic steatohepatitis (NASH)
Bile acid derivatives
Anti-lipid accumulation activities
Anti-inflammatory activities
Anti-fibrosis activities
Diterpenoids and diarylheptanoids from the fruits of
Alpinia
zerumbet
and their anti-inflammatory activity
期刊论文
OAI收割
FITOTERAPIA, 2025, 卷号: 184, 页码: 10
作者:
Zhang, Zhenghan
;
Li, Guangqian
;
Luo, Xin
;
Xiao, Fang
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Alpinia zerumbet
Labdane-type diterpenoid
Diarylheptanoid
Anti-inflammatory
ISG pathway
TDDFT ECD calculation
NMRExtractor: leveraging large language models to construct an experimental NMR database from open-source scientific publications
期刊论文
OAI收割
CHEMICAL SCIENCE, 2025, 卷号: 16, 期号: 25, 页码: 11548-11558
作者:
Wang, Qinggong
;
Zhang, Wei
;
Chen, Mingan
;
Li, Xutong
;
Xiong, Zhaoping
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20