中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [70]
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Discovery of Potent STING Inhibitors Bearing a Difluorobenzodioxol Structural Motif as Potent Anti-Inflammatory Agents
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 8, 页码: 8907-8932
作者:
Shen, Ancheng
;
Wang, Xiyuan
;
Chen, Qingxuan
;
Zhang, Yan
;
Wang, Fang
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/05/27
Molecular mechanism of the arrestin-biased agonism of neurotensin receptor 1 by an intracellular allosteric modulator
期刊论文
OAI收割
CELL RESEARCH, 2025, 卷号: 35, 期号: 4, 页码: 284-295
作者:
Sun, Demeng
;
Li, Xiang
;
Yuan, Qingning
;
Wang, Yuanxia
;
Shi, Pan
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收藏
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浏览/下载:3/0
  |  
提交时间:2025/05/27
Design, Synthesis, and Pharmacological Evaluation of Quinazoline and Quinoline Derivatives as Potent ENPP1 Inhibitors for Cancer Immunotherapy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 18
作者:
He, Jie
;
Ma, Xiaoyu
;
Sun, Jia
;
Chen, Manman
;
Xu, Lan
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/04/01
Molecular Imaging of Ovarian Follicles and Tumors With Near-Infrared II Bioconjugates
期刊论文
OAI收割
ADVANCED MATERIALS, 2024, 页码: 13
作者:
Wang, Yicong
;
Lu, Wenhan
;
Chen, Zi-Han
;
Xiao, Yan
;
Wang, Yu
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2025/02/28
biomaterials
follicular tracking
multi-color imaging
near-infrared II bioconjugates
near-infrared II in vivo imaging
Direct Reductive
N
-alkylation of Amines with Carboxylic Esters
期刊论文
OAI收割
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2024, 页码: 7
作者:
Zhang, Yuxuan
;
Bonku, Emmanuel Mintah
;
Yang, Xingbang
;
Zhu, Fuqiang
;
Jiang, Xiangrui
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/01/14
Direct reductive
N
-alkylation of amine
One-pot reaction
Grignard reagent
Amidation of ester
Cariprazine
Phosphinothio(seleno)ation of alkynes/olefins and application on the late-stage functionalization of natural products
期刊论文
OAI收割
COMMUNICATIONS CHEMISTRY, 2024, 卷号: 7, 期号: 1, 页码: 290
作者:
Shao, Chang-Wei
;
Wan, Pei-Feng
;
Xu, Quan
;
Yang, Ze-Nan
;
Geng, Mei-Yu
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/06/04
Interleukin 15-Presenting Nanovesicles with Doxorubicin-Loaded Ferritin Cores for Cancer Immunochemotherapy
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 14
作者:
Zhai, Yihui
;
Zhang, Wen
;
Wang, Jinming
;
Kong, Ying
;
Rong, Rong
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收藏
  |  
浏览/下载:25/0
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提交时间:2025/01/14
CTLs
IL15, immunotherapy
nanovesicles
NK cells
Design and synthesis of novel site-specific antibody-drug conjugates that target TROP2
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 110, 页码: 16
作者:
Luo, Caili
;
Ren, Anni
;
Jin, Zixuan
;
Zhang, Jianxin
;
Shi, Wei
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/08/22
TROP2
Antibody-drug conjugate (ADC)
Site-specific
Glycoengineering
Affinity-directed conjugation
PPIA dictates NRF2 stability to promote lung cancer progression
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1, 页码: 20
作者:
Lu, Weiqiang
;
Cui, Jiayan
;
Wang, Wanyan
;
Hu, Qian
;
Xue, Yun
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收藏
  |  
浏览/下载:30/0
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提交时间:2024/07/12
Anti-inflammatory Steroids from the South China Sea Sponge
Spongia officinalis
期刊论文
OAI收割
CHEMISTRY & BIODIVERSITY, 2024, 页码: 5
作者:
Liu, Jiao
;
Liu, Zi-Yi
;
Fu, Yan
;
Gu, Yu-Cheng
;
Li, Song-Wei
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/05/31
Sponge
Spongia officinalis
Chemical investigation
Absolute configuration
Anti-inflammatory activity