中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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西北高原生物研究所 [52]
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期刊论文 [287]
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Chat-microreactor: A large-language-model-based assistant for designing continuous flow systems
期刊论文
OAI收割
CHEMICAL ENGINEERING SCIENCE, 2025, 卷号: 311
作者:
Pan, Yongqi
;
Xiao, Qinfan
;
Zhao, Fangyu
;
Li ZH(李振豪)
;
Liu, Jianyang
  |  
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2025/04/21
Flow chemistry
Microreactor
Large language models
Machine learning
Multi-phase dispersion
Structure-activity relationship analysis of meta-substituted N-cyclopropylmethyl-nornepenthones with mixed KOR/MOR activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 289, 页码: 15
作者:
Tang, Siyuan
;
Hu, Shuyang
;
Feng, Lijing
;
Kong, Linghui
;
Gui, Jiangwen
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/05/27
N-Cyclopropylmethyl-nornepenthones
Structure-activity relationship
MOR antagonist
KOR agonist
Substance use disorder
Proteome-Wide Data Guides the Discovery of Lysine-Targeting Covalent Inhibitors Using DNA-Encoded Chemical Libraries
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 14
作者:
Wu, Xinyuan
;
Li, Shunyao
;
Liang, Ting
;
Yu, Qing
;
Zhang, Yiwei
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/06/23
Activity-based protein profiling data
Covalent DNA-encoded chemical library
Covalent ligand selection
Lysine-targeting covalent inhibitors
O
-Cyanobenzaldehydes Irreversibly Modify Both Buried and Exposed Lysine Residues in Live Cells
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2025, 卷号: 147, 期号: 14, 页码: 11955-11963
作者:
Ling, Huan
;
Li, Lin
;
Duan, Liping
;
Huang, Weixue
;
Zheng, Jiangnan
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/05/27
IHCH9033, a novel class I HDAC inhibitor, synergizes with FLT3 inhibitor and rescues quizartinib resistance in FLT3-ITD AML via enhancing DNA damage response
期刊论文
OAI收割
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2025, 卷号: 14, 期号: 1, 页码: 19
作者:
Yao, Mingyue
;
Yan, Wenzhong
;
Wang, Yafang
;
Zhao, Yu
;
Xu, Xiaowei
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/04/01
Acute myeloid leukemia
HDAC inhibitor
FLT3-ITD mutation
DNA damage response
Synergistic effect
Drug resistance
Research on rapid concentration field reconstruction method for two-dimensional geometric paths based on laser absorption spectroscopy
期刊论文
OAI收割
MEASUREMENT, 2025, 卷号: 241
作者:
Li, Qi
;
Tang, Qixing
;
Zhang, Yujun
;
Gao, Hua
;
Rao, Yuan
  |  
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2024/11/20
Laser absorption spectrum
Gas concentration reconstruction
Geometric paths
Computed tomography scan
Large-scale open space
Design, synthesis and activity evaluation of novel quinazolinone compounds as TRPC5 inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 155, 页码: 20
作者:
Bai, Longhui
;
Xiang, Yu
;
Shen, Meiling
;
Han, Yujun
;
Li, Penghua
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
TRPC5
Inhibitors
Structural modifications and optimizing
Synthesis
Quinazolinone compounds
Activity evaluation
Cannabidiol inhibits transient receptor potential canonical 4 and modulates excitability of pyramidal neurons in mPFC
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2024, 卷号: 15, 页码: 12
作者:
Han, Yujun
;
Wang, Shuting
;
Xiang, Yu
;
Chang, Liuliu
;
Wang, Xian
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/12/25
TRPC4
cannabidiol
epinephrine
inhibitor
medial prefrontal cortex
Comparative Validation and Misclassification Diagnosis of 30-Meter Land Cover Datasets in China
期刊论文
OAI收割
REMOTE SENSING, 2024, 卷号: 16, 期号: 22, 页码: 27
作者:
Xu, Xiaolin
;
Li, Dan
;
Liu, Hongxi
;
Zhao, Guang
;
Cui, Baoshan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/03/03
land cover maps
inconsistency evaluation
accuracy assessment
misclassification diagnosis
Carrier-phonon decoupling in perovskite thermoelectrics via entropy engineering
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2024, 卷号: 15
作者:
Zheng, Yunpeng
;
Zhang, Qinghua
;
Shi, Caijuan
;
Zhou, Zhifang
;
Lu, Yang
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/11/20