中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [28]
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期刊论文 [231]
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浏览/检索结果:
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Discovery of novel covalent stabilizers for p53 Y220C using structure-based drug discovery methods
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2025, 页码: 14
作者:
Wen, Yiming
;
Xu, Peijia
;
Chen, Yijie
;
Meng, Jingyi
;
Zheng, Mingyue
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/04/01
p53 Y220C
Covalent stabilizer
Virtual screening
Molecular dynamics
DNA binding
Structure-activity relationship
Cancer therapy
Design, synthesis, and structure-activity relationship studies of triazolo-pyrimidine derivatives as WRN inhibitors for the treatment of MSI tumors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 282, 页码: 21
作者:
Sui, Qibang
;
Zhou, Yuanyang
;
Li, Manjia
;
Wang, Dan
;
Cui, Rongrong
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/12/25
Synthetic lethal
MSI tumors
WRN inhibitors
Triazolo-pyrimidine derivatives
Reproductive and germ-cell mutagenic effects of poly-and perfluoroalkyl substances (PFAS) to Caenorhabditis elegans after multigenerational exposure
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2024, 卷号: 954
作者:
Cao, Zhenxiao
;
Dai, Linglong
;
Li, Jiali
;
Zhang, Jingyi
;
Wang, Xialian
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/11/20
PFAS
Multigenerational exposure
Caenorhabditis elegans
Germ cell mutagenicity
Whole genome sequencing
Reciprocal relationships among parental psychological control, emotion regulation ability, and subjective well-being of adolescents: Disentangling between- and within-person effects
期刊论文
OAI收割
JOURNAL OF AFFECTIVE DISORDERS, 2024, 卷号: 361, 页码: 546-555
作者:
Deng, Chaoqiong
;
Li, Dongping
;
Li, Yang
;
Liu, Yuxiao
;
Zhang, Jingyi
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/08/12
Parental psychological control
Subjective well-being
Emotion regulation ability
Adolescents
Random intercept cross-lagged panel model
Stillbirths Associated with Particle Pollution are Disproportionally Contributed by Sand Dust: Findings from 52 Low- and Middle-Income Countries
期刊论文
OAI收割
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2024, 卷号: 58, 期号: 36, 页码: 15971-15983
作者:
Li, Pengfei
;
Wu, Jingyi
;
Tong, Mingkun
;
Wang, Ruohan
;
Tang, Mingjin
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/10/10
particulate matter
sand dust
stillbirth
joint exposure-response function
maternal health
health inequality
Deep representation learning of chemical-induced transcriptional profile for phenotype-based drug discovery
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1, 页码: 14
作者:
Tong, Xiaochu
;
Qu, Ning
;
Kong, Xiangtai
;
Ni, Shengkun
;
Zhou, Jingyi
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/08/22
Long-term effects of climate factors on dengue fever over a 40-year period
期刊论文
OAI收割
BMC PUBLIC HEALTH, 2024, 卷号: 24, 期号: 1, 页码: 1451
作者:
Xu, Chengdong
;
Xu, Jingyi
;
Wang, Li
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/07/12
Dengue
Long-term
Climate
KinomeMETA: a web platform for kinome-wide polypharmacology profiling with meta-learning
期刊论文
OAI收割
NUCLEIC ACIDS RESEARCH, 2024, 页码: 9
作者:
Li, Zhaojun
;
Qu, Ning
;
Zhou, Jingyi
;
Sun, Jingjing
;
Ren, Qun
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/06/27
Housing-industry transformation development and rural revitalization path based on complex adaptive system in Three Gorges Reservoir Area of China
期刊论文
OAI收割
ECOLOGICAL INDICATORS, 2024, 卷号: 162, 页码: 112008
作者:
Qu, Lulu
;
Wang, Jingyi
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/06/17
Housing-industry transformation
Sustainable rural development
Complex adaptive system
Revitalization path
Three Gorges Reservoir Area
Epistasis in neurotransmitter receptors linked to posttraumatic stress disorder and major depressive disorder comorbidity in traumatized Chinese
期刊论文
OAI收割
FRONTIERS IN PSYCHIATRY, 2024, 卷号: 15, 页码: 10
作者:
Xu, Ling
;
Zhang, Jingyi
;
Yang, Haibo
;
Cao, Chengqi
;
Fang, Ruojiao
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2024/04/15
PTSD-MDD comorbidity
gene x gene interaction
single nucleotide polymorphism
neuropeptide Y
dopamine