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Discovery of pyridazinone derivatives bearing tetrahydroimidazo[1,2-
a
] pyrazine scaffold as potent inhibitors of transient receptor potential canonical 5 to ameliorate hypertension-induced renal injury in rats
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 275, 页码: 18
作者:
Xu, Yuanyuan
;
Ren, Younan
;
Zhang, Jie
;
Niu, Bo
;
Liu, Mengru
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/08/22
Pyridazinone
Tetrahydroimidazo[1,2-a]pyrazine
Transient receptor potential canonical 5
Chronic kidney disease
Focal segmental glomerulosclerosis
A novel approach to exploit Small-Molecule glucagon-like Peptide-1 receptor agonists with high potency
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 107, 页码: 19
作者:
Wang, Xiaoyan
;
Yun, Ying
;
Chen, Lili
;
Guo, Shimeng
;
Niu, Buying
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2024/07/12
Diabetes
GLP-1 receptor
Agonist
Structural optimization
Water molecule replacement
Structure activity relationship
Docking simulation
Cross-ancestry genome-wide association studies of brain imaging phenotypes
期刊论文
OAI收割
NATURE GENETICS, 2024, 页码: 31
作者:
Fu, Jilian
;
Zhang, Quan
;
Wang, Jianhua
;
Wang, Meiyun
;
Zhang, Bing
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2024/06/29
Review on Peg-in-Hole Insertion Technology Based on Reinforcement Learning
会议论文
OAI收割
Chongqing, China, 2023-11
作者:
Shen Liancheng
;
Su Jianhua
;
Zhang Xiaodong
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/06/24
—Robot Peg-in-hole Insertion
Reinforcement Learning
Meta-Reinforcement Learning
Study on Effect of Particle Size Distribution on Water-Retention Capacity of Coral Sand from Macro and Micro Perspective
期刊论文
OAI收割
JOURNAL OF MARINE SCIENCE AND ENGINEERING, 2024, 卷号: 12, 期号: 2, 页码: 20
作者:
Wu, Hao
;
Lei, Xuewen
;
Chen, Xiang
;
Shen, Jianhua
;
Wang, Xinzhi
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/27
coral sand
water-retention capacity
particle size distribution
nuclear magnetic resonance
pore water distribution
Discovery and exploration of novel somatostatin receptor subtype 5 (SSTR5) antagonists for the treatment of cholesterol gallstones
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 16
作者:
Han, Fanghui
;
Zhao, Tingting
;
Zhang, Yanglong
;
Yun, Ying
;
Xu, Yuanyuan
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/02/19
SSTR5 antagonist
Gallbladder emptying
Cholesterol gallstones
Design of a robot system for reorienting and assembling irregular parts
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF ADVANCED ROBOTIC SYSTEMS, 2024, 卷号: 21, 期号: 1, 页码: 12
作者:
Su, Jianhua
;
Shen, Liancheng
;
Peng, Zongyu
;
Qu, Xiaoyi
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/05/30
Assembly
object reorientation
force control
Discovery of a novel GPR35 agonist with high and equipotent species potency for oral treatment of IBD
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 96, 页码: 12
作者:
Song, Zhaoxiang
;
Lu, Dan
;
Sun, Jun
;
Ye, Yangliang
;
Fang, Jiahui
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2024/01/16
GPR35
IBD
Lodoxamide
Increased risk of postpartum depression in women with lactational mastitis: a cross-sectional study
期刊论文
OAI收割
FRONTIERS IN PSYCHIATRY, 2023, 卷号: 14, 页码: 8
作者:
Shen, Fuyi
;
Zhou, Xianjin
;
Guo, Fei
;
Fan, Kechen
;
Zhou, Yilu
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/12/08
lactational mastitis
depression
postpartum period
breastfeeding
cross-sectional study
Magnesium lithospermate B ameliorates diabetic nephropathy by suppressing the uremic toxin formation mediated by gut microbiota
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACOLOGY, 2023, 卷号: 953, 页码: 12
作者:
Zhu, Nanlin
;
Duan, Haonan
;
Feng, Yingying
;
Xu, Wenwei
;
Shen, Jianhua
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2023/10/17
Diabetic nephropathy
Magnesium lithospermate B
Gut microbiota
Uremic toxins
p -Cresyl sulfate metabolism