机构

• 上海药物研究所 [18]
• 上海微系统与信息技术... [7]
• 地理科学与资源研究所 [5]
• 西安光学精密机械研究... [2]
• 中国科学院大学 [1]
• 地球化学研究所 [1]
• 更多

采集方式

• OAI收割 [34]
• iSwitch采集 [1]

内容类型

• 期刊论文 [30]
• 专利 [3]
• 会议论文 [1]
• 学位论文 [1]

发表日期

• 2024 [5]
• 2023 [3]
• 2022 [2]
• 2020 [4]
• 2019 [2]
• 2017 [7]
• 更多

学科主题

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浏览/检索结果: 共35条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 A novel isoquinoline alkaloid HJ-69 isolated from Zanthoxylum bungeanum attenuates inflammatory pain by inhibiting voltage-gated sodium and potassium channels 期刊论文  OAI收割 JOURNAL OF ETHNOPHARMACOLOGY, 2024, 卷号: 330, 页码: 12 作者:  Wang, Long;  Hao, Haishuang;  Meng, Xianhua;  Zhang, Wenbo;  Zhang, Yin   |  收藏  |  浏览/下载：114/0  |  提交时间：2024/11/05 HJ-69  Zanthoxylum bungeanum  Isoquinoline alkaloid  Nav  Kv  Inflammatory pain   Discovery of Novel Pyrimidine-Based Derivatives as Nav1.2 Inhibitors with Efficacy in Mouse Models of Epilepsy 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12912-12931 作者:  He, Guoxue;  Zheng, Yueming;  Chang, Shunzhen;  Wang, Long;  Yang, Xiaohao   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/09/26 Direct Identification of Complex Glycans via a Highly Sensitive Engineered Nanopore 期刊论文  OAI收割 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2024, 页码: 11 作者:  Yao, Guangda;  Tian, Yinping;  Ke, Wenjun;  Fang, Jie;  Ma, Shengzhou   |  收藏  |  浏览/下载：18/0  |  提交时间：2024/05/22 Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses 期刊论文  OAI收割 NATURE CHEMICAL BIOLOGY, 2024, 页码: 29 作者:  Zhou, Xiaoyu;  Zhao, Cheng;  Xu, Haiyan;  Xu, Yixiang;  Zhan, Li   |  收藏  |  浏览/下载：35/0  |  提交时间：2024/03/25 An LQT2-related mutation in the voltage-sensing domain is involved in switching the gating polarity of hERG 期刊论文  OAI收割 BMC BIOLOGY, 2024, 卷号: 22, 期号: 1, 页码: 14 作者:  Liu, Zhipei;  Wang, Feng;  Yuan, Hui;  Tian, Fuyun;  Yang, Chuanyan   |  收藏  |  浏览/下载：31/0  |  提交时间：2024/03/13 hERG  K525N  Gating Polarity  Voltage-Sensing Domain  LQT2   Discovery of selective NaV1.8 inhibitors based on 5-chloro-2-(4,4-difluor- oazepan-1-yl)-6-methyl nicotinamide scaffold for the treatment of pain 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 12 作者:  Qin, Hui;  Wei, Aihuan;  Wang, Yunqi;  Wang, Linlin;  Xu, Haiyan   |  收藏  |  浏览/下载：29/0  |  提交时间：2023/10/17 Pain  Non-addictive analgesics  Na V 1  8-selective inhibitors  Bicyclic aromatic groups   Design, Synthesis and Bioactivity of [3.3.3]Propellane-Based Voltage-Gated Calcium Channel alpha 2 delta Subunit Ligands 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2023, 卷号: 43, 期号: 6, 页码: 2226-2238 作者:  He Jinyan;  Tian Fuyun;  Wu Qingqing;  Zheng Yueming;  Chen Yuting   |  收藏  |  浏览/下载：30/0  |  提交时间：2023/10/17 propellane  voltage-gated calcium channel  alpha 2 delta subunit  synthesis  bioactivity  structure-activity relationship   Characterization of the role of TMEM175 in an in vitro lysosomal H+ fluxes model 期刊论文  OAI收割 FEBS JOURNAL, 2023, 页码: 19 作者:  Yang, Chuanyan;  Tian, Fuyun;  Hu, Mei;  Kang, Chunlan;  Ping, Meixuan   |  收藏  |  浏览/下载：70/0  |  提交时间：2023/10/17 glycocalyx  H+ leak  lysosome acidification  proton channel  TMEM175   Study on structure-activity relationship (SAR) of simplified mirogabalin derivatives as voltage-gated calcium channel alpha 2 delta ligands for the treatment of chronic neuropathic pain 期刊论文  OAI收割 MEDICINAL CHEMISTRY RESEARCH, 2022, 页码: 26 作者:  Zhang, Yuanwen;  Zheng, Yueming;  Wu, Qingqing;  Tian, Fuyun;  Ma, Chuanjun   |  收藏  |  浏览/下载：40/0  |  提交时间：2023/04/10 Voltage-gated calcium channel  alpha 2 delta subunit  gamma-aminobutyric acid  Mirogabalin  Neuropathic pain  Structure-activity relationship   Epilepsy phenotype and response to KCNQ openers in mice harboring the Kcnq2 R207W voltage-sensor mutation 期刊论文  OAI收割 NEUROBIOLOGY OF DISEASE, 2022, 卷号: 174, 页码: 10 作者:  Tian, Fuyun;  Cao, Birong;  Xu, Haiyan;  Zhan, Li;  Nan, Fajun   |  收藏  |  浏览/下载：44/0  |  提交时间：2022/12/13 KCNQ2  Epilepsy  Mouse model  HN37 (pynegabine)