中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海应用物理研究所 [7]
上海药物研究所 [5]
数学与系统科学研究院 [2]
中国科学院大学 [2]
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深圳先进技术研究院 [1]
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OAI收割 [22]
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期刊论文 [24]
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2025 [1]
2024 [3]
2023 [1]
2022 [3]
2020 [1]
2019 [1]
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Physics [1]
生物资源::功能基因... [1]
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Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 156, 页码: 16
作者:
Zeng, Gongruixue
;
Xu, Gaoya
;
Gao, Lixin
;
Zheng, Xiaoli
;
Chi, Xinglong
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
Proteasome inhibitors
Macrocycle
Stability
Anti-cancer activities
Exploration of novel 20S proteasome activators featuring anthraquinone structures and their application in hypoxic cardiomyocyte protection
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 115, 页码: 10
作者:
Yu, Qian
;
Gao, Lixin
;
Xu, Linhao
;
Han, Yubing
;
Cao, Yu
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/12/11
Discovery of the First BRD4 Second Bromodomain (BD2)-Selective Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 23, 页码: 21577-21616
作者:
Li, Junhua
;
Hu, Qingqing
;
Zhu, Run
;
Dong, Ruibo
;
Shen, Hui
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/01/10
Proteasome activation: A novel strategy for targeting undruggable intrinsically disordered proteins
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 145, 页码: 17
作者:
Yu, Qian
;
Wang, Zheng
;
Tu, Yutong
;
Cao, Yu
;
Zhu, Huajian
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/05/07
20S proteasome
Proteasome activation
IDPs
Undruggable
Protein homeostasis
Exploration of novel four-membered-heterocycle constructed peptidyl proteasome inhibitors with improved metabolic stability for cancer treatment
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 138, 页码: 22
作者:
Wang, Hanlin
;
Wu, Zhaoxiao
;
Cao, Yu
;
Gao, Lixin
;
Shao, Jiaan
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/10/17
Metabolic stability
Four-membered heterocycles
Proteasome inhibitors
Multiple myeloma
Discovery and prospecting potential of volcanic beryllium mineralization in Kulongshan, northern Hebei Province.
期刊论文
OAI收割
ACTA PETROLOGICA SINICA, 2022, 卷号: 38, 期号: 7, 页码: 1901-1914
作者:
Chen ZhenYu
;
Li ShengLi
;
Li XiaoFeng
;
Pan Shuo
;
Zhang XingKang
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/03/31
Konglongshan
Alterated rocks
Volcanic Be -U deposit
Helvite
Prospecting potential
Metabolism guided optimization of peptidomimetics as non-covalent proteasome inhibitors for cancer treatment
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 233, 页码: 18
作者:
Cao, Yu
;
Tu, Yutong
;
Fu, Liping
;
Yu, Qian
;
Gao, Lixin
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2022/06/15
Metabolism
Design
Proteasome inhibitors
Non-covalent
Multiple myeloma
Order reduction-based uniform approximation of exponential stability for one-dimensional Schrodinger equation
期刊论文
OAI收割
SYSTEMS & CONTROL LETTERS, 2022, 卷号: 160, 页码: 9
作者:
Liu, Jiankang
;
Hao, Ruiqi
;
Guo, Bao-Zhu
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/06/21
Schrodinger equation
Exponential stability
Uniform approximation
Order reduction method
Counteraction of ABA-Mediated Inhibition of Seed Germination and Seedling Establishment by ABA Signaling Terminator in Arabidopsis
期刊论文
OAI收割
MOLECULAR PLANT, 2020, 卷号: 13, 期号: 9, 页码: 1284-1297
作者:
Wang, Zhijuan
;
Ren, Ziyin
;
Cheng, Chunhong
;
Wang, Tao
;
Ji, Hongtao
  |  
收藏
  |  
浏览/下载:213/0
  |  
提交时间:2020/11/30
ABA
ABT
ABA signaling
PYR1/PYL/RCAR-ABA-PP2Cs complex
seed germination
post-germinative development
A novel semi-discrete scheme preserving uniformly exponential stability for an Euler-Bernoulli beam
期刊论文
OAI收割
SYSTEMS & CONTROL LETTERS, 2019, 卷号: 134, 页码: 10
作者:
Liu, Jiankang
;
Guo, Bao-Zhu
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/05/24
Beam equation
Finite volume method
Finite difference method
Exponential stability
Uniform approximation