中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [28]
上海应用物理研究所 [1]
中国科学院大学 [1]
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OAI收割 [29]
iSwitch采集 [1]
内容类型
期刊论文 [28]
会议论文 [2]
发表日期
2023 [1]
2021 [1]
2020 [2]
2019 [5]
2018 [4]
2017 [2]
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学科主题
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Sodium Oligomannate Electrostatically Binds to Aβ and Blocks Its Aggregation
期刊论文
OAI收割
JOURNAL OF PHYSICAL CHEMISTRY B, 2023
作者:
Zhou, Chen
;
Zhang, Jingjing
;
Luo, Xinwen
;
Lian, Fulin
;
Zeng, Yangyang
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/03/27
5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19
作者:
Wang, Shuni
;
Yang, Hong
;
Su, Mingbo
;
Lian, Fulin
;
Cong, Zhanqing
  |  
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2021/11/04
NSD2
Methyltransferase
HTS
Multiple myeloma
5-Aminonaphthalene derivatives
Inhibitor
Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion
期刊论文
OAI收割
ADVANCED SCIENCE, 2020, 页码: 13
作者:
Sun, Zhongya
;
Zhang, Hao
;
Zhang, Yuanyuan
;
Liao, Liping
;
Zhou, Wen
  |  
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2020/07/01
anti-metastasis activities
crystal structures
inhibitors
novel pockets
rho family proteins
A Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression
期刊论文
OAI收割
CANCER RESEARCH, 2020, 卷号: 80, 期号: 3, 页码: 536-548
作者:
Wang, Yingcong
;
Huang, Jing
;
Li, Bo
;
Xue, Han
;
Tricot, Guido
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2020/07/01
Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 15
作者:
Lu, Wenchao
;
Wang, Jun
;
Li, Yong
;
Tao, Hongru
;
Xiong, Huan
  |  
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2020/07/01
Hippo pathway
TEAD transcription factor
Covalent inhibitor
Palmitoylation inhibitor
Discovery of alkoxy benzamide derivatives as novel BPTF bromodomain inhibitors via structure-based virtual screening
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2019, 卷号: 86, 页码: 494-500
作者:
Zhang, Dan
;
Han, Jie
;
Lu, Wenchao
;
Lian, Fulin
;
Wang, Jun
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/07/01
Lysine acetylation
Bromodomain
Virtual screening
BPTF inhibitor
Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia
期刊论文
OAI收割
CANCER CELL, 2019, 卷号: 35, 期号: 4, 页码: 677-+
作者:
Huang, Yue
;
Su, Rui
;
Sheng, Yue
;
Dong, Lei
;
Dong, Ze
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
The identification of novel small-molecule inhibitors targeting WDR5-MLL1 interaction through fluorescence polarization based high-throughput screening
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 4, 页码: 638-645
作者:
Ye, Xiaoqing
;
Zhang, Rukang
;
Lian, Fulin
;
Zhang, Weiyao
;
Lu, Wenchao
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
WDR5-MLL1 interaction
Leukemia
Small-molecule
High-throughput screening
Fluorescence polarization (FP)
Fragment-based drug discovery of triazole inhibitors to block PDE delta-RAS protein-protein interaction
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 163, 页码: 597-609
作者:
Chen, Danqi
;
Chen, Yuehong
;
Lian, Fulin
;
Chen, Liu
;
Li, Yanlian
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
PDE delta-RAS
Fragment-based
Inhibitor
Protein-protein interaction
Fragment-based drug discovery of triazole inhibitors to block PDEδ-RAS protein-protein interaction
期刊论文
OAI收割
European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 597-609
作者:
Chen, Danqi
;
Chen, Yuehong
;
Lian, Fulin
;
Chen, Liu
;
Li, Yanlian
  |  
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2019/01/08