中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共22条,第1-10条 帮助

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Design and synthesis of cantharidin derivative DCZ5418 as a TRIP13 inhibitor with anti-multiple myeloma activity in vitro and in vivo 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 98, 页码: 7
作者:  
Dong, Sanfeng;  Hu, Ke;  Shi, Yulong;  Wang, Guanli;  Yu, Dandan
  |  收藏  |  浏览/下载:10/0  |  提交时间:2024/02/19
The novel norcantharidin derivative DCZ5417 suppresses multiple myeloma progression by targeting the TRIP13-MAPK-YWHAE signaling pathway 期刊论文  OAI收割
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 卷号: 21, 期号: 1, 页码: 17
作者:  
Wang, Yingcong;  Dong, Sanfeng;  Hu, Ke;  Xu, Li;  Feng, Qilin
  |  收藏  |  浏览/下载:12/0  |  提交时间:2024/01/26
Aberrant activation of TRIP13-EZH2 signaling axis promotes stemness and therapy resistance in multiple myeloma 期刊论文  OAI收割
LEUKEMIA, 2023, 页码: 4
作者:  
Xu, Li;  Wang, Yingcong;  Wang, Guanli;  Guo, Shushan;  Yu, Dandan
  |  收藏  |  浏览/下载:22/0  |  提交时间:2023/10/17
Preclinical validation and phase I trial of 4-hydroxysalicylanilide, targeting ribonucleotide reductase mediated dNTP synthesis in multiple myeloma 期刊论文  OAI收割
Journal of Biomedical Science, 2022, 卷号: 29, 期号: 1
作者:  
Xie,Yongsheng;  Wang,Yingcong;  Xu,Zhijian;  Lu,Yumeng;  Song,Dongliang
  |  收藏  |  浏览/下载:27/0  |  提交时间:2022/06/15
DCZ0014, a novel compound in the therapy of diffuse large B-cell lymphoma via the B cell receptor signaling pathway 期刊论文  OAI收割
NEOPLASIA, 2022, 卷号: 24, 期号: 1, 页码: 50-61
作者:  
Chang, Shuaikang;  Li, Bo;  Xie, Yongsheng;  Wang, Yingcong;  Xu, Zhijian
  |  收藏  |  浏览/下载:25/0  |  提交时间:2022/06/15
A novel silicone derivative of natural osalmid (DCZ0858) exerts anti-multiple myeloma activity by promoting cell apoptosis and inhibiting cell cycle and mTOR signaling 期刊论文  OAI收割
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2021, 卷号: 13, 期号: 10, 页码: 11439-11449
作者:  
Bu, Wenxuan;  Li, Bo;  Feng, Lijin;  Feng, Qilin;  Hu, Ke
  |  收藏  |  浏览/下载:20/0  |  提交时间:2021/12/16
A novel M phase blocker, DCZ3301 enhances the sensitivity of bortezomib in resistant multiple myeloma through DNA damage and mitotic catastrophe 期刊论文  OAI收割
Journal of Experimental & Clinical Cancer Research, 2020, 卷号: 39, 期号: 1
作者:  
Hu,Liangning;  Li,Bo;  Chen,Gege;  Song,Dongliang;  Xu,Zhijian
  |  收藏  |  浏览/下载:44/0  |  提交时间:2020/07/01
A novel phosphoramide compound, DCZ0847, displays in vitro and in vivo anti-myeloma activity, alone or in combination with bortezomib 期刊论文  OAI收割
CANCER LETTERS, 2020, 卷号: 478, 页码: 45-55
作者:  
Chen, Gege;  Hu, Ke;  Sun, Haiguo;  Zhou, Jinfeng;  Song, Dongliang
  |  收藏  |  浏览/下载:31/0  |  提交时间:2020/07/01
A novel silicone derivative of natural osalmid (DCZ0858) induces apoptosis and cell cycle arrest in diffuse large B-cell lymphoma via the JAK2/STAT3 pathway 期刊论文  OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 卷号: 5, 期号: 1, 页码: 11
作者:  
Lu, Kang;  Li, Bo;  Zhang, Hui;  Xu, Zhijian;  Song, Dongliang
  |  收藏  |  浏览/下载:29/0  |  提交时间:2020/07/01
Inhibition of JNK ameliorates depressive-like behaviors and reduces the activation of pro-inflammatory cytokines and the phosphorylation of glucocorticoid receptors at serine 246 induced by neuroinflammation 期刊论文  OAI收割
PSYCHONEUROENDOCRINOLOGY, 2020, 卷号: 113, 页码: 10
作者:  
Zhang, Juntao;  Lin, Wenjuan;  Tang, Mingming;  Zhao, Yawei;  Zhang, Ke
  |  收藏  |  浏览/下载:56/0  |  提交时间:2020/05/18