中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [14]
半导体研究所 [7]
近代物理研究所 [7]
合肥物质科学研究院 [6]
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Identifying a non-conserved site for achieving allosteric covalent inhibition of CECR2
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 16
作者:
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/04/01
dynamics simulation
CECR2
covalent inhibitor
allosteric effect
Age-related decline in CD8
+
tissue resident memory T cells compromises antitumor immunity
期刊论文
OAI收割
NATURE AGING, 2024, 卷号: 4, 期号: 12, 页码: 1828-+
作者:
Pei, Siyu
;
Deng, Xiuyu
;
Yang, Ruirui
;
Wang, Hui
;
Shi, Jian-Hong
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/02/28
Analysis of Herbal Constituents and In Vivo Pharmacokinetics of
Gegen-Huangqi
Decoction in Rat Plasma Using HPLC-Q-TOF-MS/MS and HPLC-QQQ-MS/MS
期刊论文
OAI收割
BIOMEDICAL CHROMATOGRAPHY, 2024, 页码: 16
作者:
Xu, Zhou
;
Wang, Linwei
;
Liu, Huan
;
Tian, Xiaoting
;
Wang, Yangyang
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/12/25
gegen-huangqi
decoction
hepatic disposition
LC-MS/MS
pharmacokinetics
qualitative
Deciphering deep-sea chemosynthetic symbiosis by single-nucleus RNA-sequencing
期刊论文
OAI收割
ELIFE, 2024, 卷号: 12, 页码: 26
作者:
Wang, Hao
;
He, Kai
;
Zhang, Huan
;
Zhang, Quanyong
;
Cao, Lei
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/12/20
cold-seep
chemosynthetic endosymbiosis
snRNA-seq
cell atlas
Gigantidas platifrons
transplantation
Other
Single-cell RNA-seq reveals distinct metabolic "microniches" and close host-symbiont interactions in deep-sea chemosynthetic tubeworm
期刊论文
OAI收割
SCIENCE ADVANCES, 2024, 卷号: 10, 期号: 30, 页码: 16
作者:
Wang, Hao
;
Xiao, Hongxiu
;
Feng, Buhan
;
Lan, Yi
;
Fung, Cheuk Wang
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/08/30
Flexible scaffold-based cheminformatics approach for polypharmacological drug design
期刊论文
OAI收割
CELL, 2024, 卷号: 187, 期号: 9, 页码: 38
作者:
Chen, Zhangcheng
;
Yu, Jing
;
Wang, Huan
;
Xu, Peiyu
;
Fan, Luyu
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/07/12
Effect of interface morphology on the heterogeneous development of bedding-perpendicular joints in soft-hard interbedded strata
期刊论文
OAI收割
JOURNAL OF STRUCTURAL GEOLOGY, 2024, 卷号: 180, 页码: 11
作者:
Bao, Han
;
Li, Xiaoguang
;
Lan, Hengxing
;
Pei, Runsheng
;
Yan, Changgen
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/04/19
Soft -hard interbedded strata
Bedding -perpendicular joints
Heterogeneity
Interface morphology
Macro -micro scale
3D printing
Technological diversity in the tropical-subtropical zone of Southwest China during the terminal Pleistocene: excavations at Fodongdi Cave
期刊论文
OAI收割
ARCHAEOLOGICAL AND ANTHROPOLOGICAL SCIENCES, 2024, 卷号: 16, 期号: 1, 页码: 23
作者:
Huan, Fa-Xiang
;
Yang, Shi-Xia
;
Gao, Feng
;
Zhou, Xin-Ying
;
Yue, Jian-Ping
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2024/03/27
Lithic technology
Southwest China
Terminal Pleistocene
Human adaptation
Bispecific antibody targeting both B7-H3 and PD-L1 exhibits superior antitumor activities
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 9
作者:
Li, Hua-ying
;
Chen, Yi-li
;
Deng, Xiang-nan
;
Li, Huan-huan
;
Tan, Jie
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2023/10/17
cancer immunotherapy
B7-H3
PD-L1
bispecific antibodies
VHH
antibody-dependent cell-mediated cytotoxicity (ADCC)
Distribution patterns of landslides triggered by the 2022 Ms 6.8 Luding earthquake, Sichuan, China
期刊论文
OAI收割
JOURNAL OF MOUNTAIN SCIENCE, 2023, 卷号: N/A
作者:
Zhang, Jian-qiang
;
Yang, Zong-ji
;
Meng, Qing-kai
;
Wang, Jiao
;
Hu, Kai-heng
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/01/04
2022 Luding earthquake
Earthquake-triggered landslide
Landslide inventory
Distribution patterns