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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [8]
化学研究所 [2]
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期刊论文 [19]
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2024 [1]
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2019 [2]
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Synthesis and biological evaluation of 4-imidazolidinone-containing compounds as potent inhibitors of the MDM2/p53 interaction
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 270, 页码: 16
作者:
Lin, Zhitong
;
Liu, Chen
;
Yan, Ziqin
;
Cheng, Jing
;
Wang, Xiancheng
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/06/27
MDM2
p53
p21
Imidazolidinone
Apoptosis
A chemical perspective on the modulation of TEAD transcriptional activities: Recent progress, challenges, and opportunities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243, 页码: 31
作者:
Lou, Jianfeng
;
Lu, Yuhang
;
Cheng, Jing
;
Zhou, Feilong
;
Yan, Ziqin
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/12/13
TEAD
YAP
Palmitoylation
Protein-protein interaction
Covalent inhibitor
A Bio-based healable/renewable polyurethane elastomer derived from L-Tyrosine/Vanillin/Dimer acid
期刊论文
OAI收割
CHEMICAL ENGINEERING SCIENCE, 2022, 卷号: 258, 页码: 13
作者:
Xu, Bowen
;
Yin, Qichen
;
Han, Feilong
;
Cheng, Jue
;
Zhao, Jingbo
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/02/24
Bio-based Polyurethane
Self-healing Materials
Blocked Isocyanates
Imine Metathesis
Discovery of a selective and covalent small-molecule inhibitor of BFL-1 protein that induces robust apoptosis in cancer cells
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 236, 页码: 114327
作者:
Feng, Xuexin
;
Yan, Ziqin
;
Zhou, Feilong
;
Lou, Jianfeng
;
Lyu, Xilin
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2024/03/21
BFL-1
Apoptosis
Covalent inhibitor
Cytochrome c
BCL-2
Protein-Protein interaction
Recent Progress and Clinical Development of Inhibitors that Block MDM4/p53 Protein-Protein Interactions
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 15, 页码: 10621-10640
作者:
Zhang, Shiyan
;
Lou, Jianfeng
;
Li, Yafang
;
Zhou, Feilong
;
Yan, Ziqin
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/11/04
Concise and Efficient Self-Healing Cross-Linked Polyurethanes via the Blocking/Deblocking Reaction of Oxime Urethanes
期刊论文
OAI收割
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 2021, 卷号: 60, 期号: 30, 页码: 11095-11105
作者:
Xu, Bowen
;
Han, Feilong
;
Pei, Xuqiang
;
Zhang, Suojiang
;
Zhao, Jingbo
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2021/10/15
Discovery of a novel, potent and selective small-molecule inhibitor of PD-1/PD-L1 interaction with robust in vivo anti-tumour efficacy
期刊论文
OAI收割
BRITISH JOURNAL OF PHARMACOLOGY, 2021, 页码: 20
作者:
Liu, Chenglong
;
Zhou, Feilong
;
Yan, Ziqin
;
Shen, Lian
;
Zhang, Xichen
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/06/11
immunotherapy
PD-1/PD-L1
TGF-beta
tumour immune microenvironment
Surface morphology and payload synergistically caused an enhancement of the longitudinal relaxivity of a Mn3O4/PtOx nanocomposite for magnetic resonance tumor imaging
期刊论文
OAI收割
BIOMATERIALS SCIENCE, 2021, 卷号: 9
作者:
Ji, Sihan
;
Chen, Yaodong
;
Zhao, Xianglong
;
Cai, Yunyu
;
Zhang, Xiaopeng
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/05/17
Pharmacological inhibition of NF-kappa B-inducing kinase (NIK) with small molecules for the treatment of human diseases
期刊论文
OAI收割
RSC MEDICINAL CHEMISTRY, 2021, 卷号: 12, 期号: 4, 页码: 552-565
作者:
Cheng, Jing
;
Feng, Xuexin
;
Li, Zhiqiang
;
Zhou, Feilong
;
Yang, Jin-Ming
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/08/17
Lewis Acids Promoted 3+2 Cycloaddition of Oxaziridines and Cyclic Allylic Alcohols through Carbonyl Imine Intermediates
期刊论文
OAI收割
JOURNAL OF ORGANIC CHEMISTRY, 2019, 卷号: 84, 期号: 7, 页码: 4282-4293
作者:
Zhao, Erbao
;
Zhou, Feilong
;
Zhao, Yujun
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01