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浏览/检索结果: 共287条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 Heterocycle-fused phenylcyclohexylamines as novel multi-target antagonists of N-methyl-D-aspartate (NMDA) receptor and monoamine transporter for treating depression 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 20 作者:  Zheng, Fuqiang;  Hu, Zhengtao;  Chen, Hai;  Cheng, Jiaxin;  Hou, Qiongqiong   |  收藏  |  浏览/下载：3/0  |  提交时间：2025/06/23 Heterocycle-fused phenylcyclohexylamines  Multi-target antagonists  NMDAR  Monoamine transporter  Antidepressants   Development of RelB-targeting small-molecule inhibitors of non-canonical NF-kB signaling with antitumor efficacy 期刊论文  OAI收割 MOLECULAR THERAPY, 2025, 卷号: 33, 期号: 4, 页码: 1519-1534 作者:  Li, Cuifeng;  Wei, Shuqi;  Sun, Donglin;  Yang, Zhuo;  Wang, Qi   |  收藏  |  浏览/下载：3/0  |  提交时间：2025/05/27 Identification of the VP37 pocket of monkeypox virus as a promising target for pan-orthopoxvirus inhibitors through virtual screening and antiviral assays 期刊论文  OAI收割 EMERGING MICROBES & INFECTIONS, 2024, 卷号: 13, 期号: 1, 页码: 4 作者:  Huo, Shuting;  Wu, Leyun;  Huang, Baoying;  Liu, Nan;  Sun, Jiewei   |  收藏  |  浏览/下载：22/0  |  提交时间：2024/08/22 Berberine Derivative B68 Promotes Tumor Immune Clearance by Dual-Targeting BMI1 for Senescence Induction and CSN5 for PD-L1 Degradation 期刊论文  OAI收割 ADVANCED SCIENCE, 2024, 页码: 21 作者:  Hu, Hongmei;  Wang, Qun;  Yu, Dianping;  Tao, Xiaoyu;  Guo, Mengmeng   |  收藏  |  浏览/下载：13/0  |  提交时间：2025/02/28 BMI1  colorectal cancer  CSN5  PD-L1  tumor cell senescence   F-CPI: A Multimodal Deep Learning Approach for Predicting Compound Bioactivity Changes Induced by Fluorine Substitution 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 13 作者:  Zhang, Qian;  Yin, Wenhai;  Chen, Xinyao;  Zhou, Aimin;  Zhang, Guixu   |  收藏  |  浏览/下载：19/0  |  提交时间：2025/02/28 Development of an FAP-Targeted PET Probe Based on a Novel Quinolinium Molecular Scaffold 期刊论文  OAI收割 BIOCONJUGATE CHEMISTRY, 2024, 页码: 9 作者:  Li, Lei;  Cao, Rui;  Chen, Kaixin;  Qu, Chunrong;  Qian, Kun   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/08/22 Switchable Regioselective C-H Activation/Annulation of Acrylamides with Alkynes for the Synthesis of 2-Pyridones 期刊论文  OAI收割 CHEMSUSCHEM, 2024, 页码: 9 作者:  Chen, Chao;  Chen, Yanni;  Han, Zijian;  Huang, Yujie;  Wang, Yujiao   |  收藏  |  浏览/下载：29/0  |  提交时间：2024/06/27 C-H activation  [4+2] annulation  switchable regioselectivity  2-pyridones  redox-neutral   Ribosomal protein S3 mediates drug resistance of proteasome inhibitor: potential therapeutic application in multiple myeloma 期刊论文  OAI收割 HAEMATOLOGICA, 2024, 卷号: 109, 期号: 4, 页码: 1206-1219 作者:  Chen, Gege;  Gao, Xuejie;  Jia, Xinyan;  Wang, Yingcong;  Xu, Li   |  收藏  |  浏览/下载：39/0  |  提交时间：2024/05/07 A novel pterostilbene compound DCZ0825 induces macrophage M1 differentiation and Th1 polarization to exert anti-myeloma and immunomodulatory 期刊论文  OAI收割 INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 卷号: 127, 页码: 14 作者:  Zhang, Hui;  Hu, Ke;  Lu, Yumeng;  Xu, Zhijian;  Chen, Gege   |  收藏  |  浏览/下载：42/0  |  提交时间：2024/03/25 Multiple myeloma  M1 macrophages  Th1 cells  Immunomodulatory   Dihydrocelastrol induces antitumor activity and enhances the sensitivity of bortezomib in resistant multiple myeloma by inhibiting STAT3-dependent PSMB5 regulation 期刊论文  OAI收割 ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 卷号: 55, 期号: 12, 页码: 1884-1891 作者:  Jin, Shuhan;  Li, Bo;  Zhang, Bibo;  Gao, Xuejie;  Jia, Xinyan   |  收藏  |  浏览/下载：41/0  |  提交时间：2024/02/27 dihydrocelastrol  multiple myeloma  JAK2/STAT3  PSMB5  bortezomib resistance