中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Structural optimization of phthalazine derivatives for anti-HBV activities to improve oral bioavailability
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 10
作者:
Yang, Yurong
;
Xiao, Fuling
;
Zuo, Jianping
;
Yang, Li
;
Hu, Youhong
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
HBV
Capsid assembly modulators
Structural optimization
Oxidative metabolism
Design and synthesis of CDK9/EZH2 dual-target inhibitors to achieve synergistic antitumor effects
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 14
作者:
Tian, Lina
;
Xiao, Jian
;
Zeng, Yanping
;
Li, Yangsha
;
Wei, Aihuan
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
CDK9
EZH2
Dual target inhibitor
DLBCL
Human gut
Bifidobacterium longum
subsp.
suillum
is enriched in vitro by a pectic polysaccharide isolated from the flowers of
Lilium lancifolium
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2025, 卷号: 364, 页码: 14
作者:
Li, Meixia
;
Liu, Renjie
;
Wang, Tao
;
Duo, Lana
;
Chen, Guo
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Polysaccharides
Lilium lancifolium
Human gut microbiota
Bifidobacterium longum subsp. suillum
Discovery of potent anti-idiopathic pulmonary fibrosis (IPF) agents based on an o-aminopyridinyl alkynyl scaffold
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 15
作者:
Wang, Yang
;
Fan, Wenhui
;
Guo, Yihao
;
Sun, Li
;
Hu, Youhong
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/08/20
IPF
EMT
Key kinases
Inhibitors
Discovery of novel Ebola entry inhibitors with 1,2,3,4-tetrahydroisoquinoline-3-carboxamide based on (3S,4aS,8aS)-2-(3-amino-2-hydroxypropyl) decahydroisoquinoline-3-carboxamide scaffold
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 123, 页码: 4
作者:
Lin, Junzhen
;
Xiao, Fuling
;
Han, Sheng
;
Hu, Youhong
;
Zuo, Jianping
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/06/23
Ebola virus entry inhibitor
Tetrahydroisoquinoline
Immunosuppressive nitrogen-containing triterpenoid saponins from
Mussaenda
erosa
and the therapeutic efficacy of heinsiagenin A in a murine lupus erythematosus model
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 11
作者:
Xu, Yidan
;
Xiang, Mai
;
Chang, Yuan
;
Chen, Zhenhua
;
Zhang, Rujun
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Mussaenda erosa
Nitrogen-containing triterpenoid saponins
Immunosuppressive activity
Autoimmune diseases
Heinsiagenin A
Spectroastrometry and Reverberation Mapping of Active Galactic Nuclei. II. Measuring Geometric Distances and Black Hole Masses of Four Nearby Quasars
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2025, 卷号: 988, 期号: 1
作者:
Li, Yan-Rong
;
Shangguan, Jinyi
;
Wang, Jian-Min
;
Davies, Ric
;
Santos, Daryl J. D.
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2025/07/21
NMRExtractor: leveraging large language models to construct an experimental NMR database from open-source scientific publications
期刊论文
OAI收割
CHEMICAL SCIENCE, 2025, 卷号: 16, 期号: 25, 页码: 11548-11558
作者:
Wang, Qinggong
;
Zhang, Wei
;
Chen, Mingan
;
Li, Xutong
;
Xiong, Zhaoping
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
Native Ligand-Inspired peptides for c-MET targeted PET probes development
期刊论文
OAI收割
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2025, 页码: 18
作者:
Luo, Renli
;
Tan, Boyu
;
Zhang, Ying
;
Hu, Jing
;
Lin, Jia
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
C-MET
Native ligand
HGF
PET/CT imaging
Radiopharmaceuticals
Peptide probes
Multiple flares and asymmetric broad emission lines in a recurring changing-look active galactic nucleus
期刊论文
OAI收割
ASTRONOMY & ASTROPHYSICS, 2025, 卷号: 698
作者:
Guo, Wei-Jian
;
Zhang, Zhi-Xiang
;
Moiseev, Alexei
;
Fawcett, Victoria A.
;
Chen, Yong-Jie
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2025/06/23
galaxies: active
galaxies: nuclei
quasars: supermassive black holes